5 results match your criteria: "University of Alabama at Birmingham Department of Pediatrics[Affiliation]"

Objectives: We examined gestational age (GA) estimates for live and still births, and prematurity rates based on last menstrual period (LMP) compared with ultrasonography (USG) among pregnant women at seven sites in six low-resource countries.

Design: Prospective cohort study SETTING AND PARTICIPANTS: This study included data from the Global Network's population-based Maternal and Newborn Health Registry which follows pregnant women in six low-income and middle-income countries (Democratic Republic of the Congo, Guatemala, India, Kenya, Pakistan and Zambia). Participants in this analysis were 42 803 women, including their 43 230 babies, who registered for the study in their first trimester based on GA estimated either by LMP or USG and had a live or stillbirth with an estimated GA of 20-42 weeks.

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Article Synopsis
  • - Epidermal Nevus Syndrome (ENS) is a condition caused by a mutation in the Rat Sarcoma genes, resulting in increased fibroblast growth factor 23 (FGF23) levels, which disrupt phosphate balance and lead to symptoms like bone pain, muscle weakness, and fractures.
  • - Burosumab, an IgG1 monoclonal antibody that inhibits FGF23 activity, has shown promise as a treatment for disorders with elevated FGF23, successfully increasing serum phosphate levels and minimizing impacts on calcium and vitamin D metabolism.
  • - In a case study of a pediatric patient with ENS treated with Burosumab, serum phosphorus levels improved; however, complications arose with elevated parathyroid hormone and calcium, later identified
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Continuous glucose monitors (CGMs) are a tool that can reduce the burden of self-monitoring of glucose values in children and adults with type 1 diabetes (T1D), are associated with improved glycemic control, and are associated with reduced fear of hypoglycemia. Unfortunately, disparities in access to CGM exist and rates of CGM access in Alabama in 2019 were below national averages. We aimed to increase CGM access and reduce disparities in access by race, insurance status, and high-risk diabetes status.

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Introduction: We hypothesize that intraoperative parathyroid hormone (ioPTH) measurement after a total thyroidectomy predicts children at risk for hypoparathyroidism and allow for outpatient procedure.

Methods: Between 2015 and 2019, we reviewed all patients under the age of 21 undergoing a thyroidectomy (total or lobectomy). Based on the ioPTH concentration, the patients were treated by the following protocol: a) PTH ≥20 pg/mL: no treatment; b) PTH = 10-19 pg/mL: 1000 mg calcium orally TID; c) PTH = 5-9 pg/mL: calcitriol 250 μg orally BID plus 1000 mg calcium orally TID; or d) PTH <5 pg/mL calcitriol 500 μg orally BID plus 1000 mg calcium orally TID.

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