3 results match your criteria: "University of Alabama at Birmingham Center for Health Promotion[Affiliation]"

The use of prophylactic measures, including perioperative antibiotics, for the prevention of surgical site infections is a standard of care across surgical specialties. Unfortunately, the routine guidelines used for routine procedures do not always account for many of the factors encountered with urgent/emergent operations and critically ill or high-risk patients. This clinical consensus document created by the American Association for the Surgery of Trauma Critical Care Committee is one of a three-part series and reviews surgical and procedural antibiotic prophylaxis in the surgical intensive care unit.

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Article Synopsis
  • Heart transplantation for infants with hypoplastic left heart syndrome has seen significant success since the 1980s, with about 90% of children reaching their first year post-transplant thanks to advancements in clinical practices and research.
  • Despite these improvements, challenges remain in ensuring long-term survival into adulthood, particularly due to high wait-list mortality and issues like cardiac allograft vasculopathy, which can lead to transplant failure.
  • There is a need for targeted funding and research that addresses the unique risks faced by pediatric transplant recipients, as current funding heavily favors adult patients, limiting progress in pediatric care.
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Objectives: To evaluate systemic lupus erythematosus (SLE) flares following hydroxychloroquine (HCQ) reduction or discontinuation versus HCQ maintenance.

Methods: We analysed prospective data from the Systemic Lupus International Collaborating Clinics (SLICC) cohort, enrolled from 33 sites within 15 months of SLE diagnosis and followed annually (1999-2019). We evaluated person-time contributed while on the initial HCQ dose ('maintenance'), comparing this with person-time contributed after a first dose reduction, and after a first HCQ discontinuation.

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