1 results match your criteria: "University of Alabama at Birmingham (J.G.J.[Affiliation]"

Diurnal Control of Blood Pressure Is Uncoupled From Sodium Excretion.

Hypertension

June 2020

From the Section of Cardio-Renal Physiology and Medicine, Division of Nephrology, Department of Medicine, University of Alabama at Birmingham (J.G.J., B.K.B., M.K., R.H.S., M.K.R., B.T., C.J., K.A.H., J.S.P., D.M.P.).

The diurnal rhythms of sodium handling and blood pressure are thought to be regulated by clock genes, such as Bmal1. However, little is known about the regulation of these factors by Bmal1, especially in rats. Using a novel whole-body Bmal1 knockout rat model (), we hypothesized that time of day regulation of sodium excretion is dependent on Bmal1.

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