636 results match your criteria: "University of Agricultural Science[Affiliation]"

Background: Inflammation-induced oxidative stress is a pathophysiological mechanism of inflammatory diseases. Treatments targeting oxidative stress can reduce inflammatory tissue damage.

Objectives: This study aimed to conduct phytochemical analysis and evaluate the antioxidant effects of the hydroalcoholic extract of blossoms () and rhizomes ().

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Vasculo-Protective Effects of Standardized Black Chokeberry Extracts in Mice Aorta.

Int J Mol Sci

December 2024

Department III Functional Sciences-Pathophysiology, Faculty of Medicine, "Victor Babeș" University of Medicine and Pharmacy of Timișoara, E. Murgu Sq., No. 2, 300041 Timisoara, Romania.

Black chokeberry ( Elliot) represents a rich source of dietary polyphenols and other bioactive phytochemicals with pleiotropic beneficial cardiovascular effects. The present study was aimed at evaluating the ex vivo effects of two black chokeberry extracts (BChEs), obtained from either dry (DryAr) or frozen (FrozAr) berries, on oxidative stress and vascular function in mice aortic rings after incubation with angiotensin 2 (Ang 2), lipopolysaccharide (LPS) and glucose (GLUC) in order to mimic renin-angiotensin system activation, inflammation and hyperglycemia.

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Risk assessment of food additives including dietary exposure.

EFSA J

December 2024

Departamento de Nutrición y Bromatología, Toxicología y Medicina Legal, Facultad de Farmacia Universidad de Sevilla Sevilla Spain.

Lately, the entire society's focus has turned towards consuming more natural food products and the production of chemicals obtained utilising green technologies. The use of chemicals as food additives is a concern for consumers. For this reason, the search for natural and more sustainable additives is a key step to control food risks while meeting consumers' requirements.

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The optimization of cryopreservation media to reduce oxidative damage on post-thaw spermatozoa is crucial. This research aimed to assess the antioxidant properties of curcumin-loaded niosomal nanocarriers (CurLNN) on the functional characteristics, the relative expression of apoptotic genes, and flow cytometry assessments of apoptotic-like changes, reactive oxygen species production (ROS), mitochondrial membrane potential, and chromatin integrity in stallion spermatozoa following thawing. Twenty-five ejaculates were diluted in INRA96 freezing media supplemented with 20 μM of either curcumin (Cur) or CurLNN and then cryopreserved.

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L., also known as licorice, belongs to the family and is one of the most commercially valuable plants worldwide, being used in the pharmaceutical, cosmetic, and food industries, both for its therapeutic benefits as well as for the sweetening properties of the extract. This study evaluates the phytochemical composition, the biological activities, and the safety profile of a methanolic extract of licorice root (LRE) obtained from Romania.

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The current study evaluated the impact of dietary curcumin nano-micelles (CNM) on the quality of Longissimus lumborum (LL) muscle in lambs during long-term freezing storage. Thirty-two crossbred male lambs were assigned into four groups receiving 0, 20, 40, or 80 mg CNM daily over a 97-day fattening period. Meat samples were analyzed for quality attributes over nine months of freezing.

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Copper nanoparticles (CuNPs) are increasingly used across various industries due to their catalytic, antimicrobial, and electrical properties. However, their potential toxicity in aquatic environments, particularly to non-target organisms like fish, remains poorly understood. This study investigated the effects of CuNP exposure on rainbow trout () by comprehensively evaluating hematological, biochemical, antioxidant, molecular, and histopathological parameters.

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The effect of nanoceria on the alginate-gum arabic crosslinking mechanism and in vitro behavior as a wound dressing.

Int J Biol Macromol

December 2024

Nanostructured Materials and Bio-Nano-Interfaces Center, Interdisciplinary Research Institute on Bio-Nano-Sciences, Babes-Bolyai University, T. Laurian 42, 400271 Cluj-Napoca, Romania; Faculty of Physics, Babes-Bolyai University, M. Kogălniceanu 1, 400084 Cluj-Napoca, Romania; Institute for Research-Development-Innovation in Applied Natural Sciences, Babes-Bolyai University, Fântânele 30, 400294 Cluj-Napoca, Romania. Electronic address:

Medical practice has proven that chronic wounds can be treated successfully if the dressing is chosen according to the healing phase of the wound. Correct intervention from the hemostasis and inflammatory phase can prevent oxidative stress and ensure optimal conditions for healing. It is important to design a new wound dressing that does not cause additional injury, has an antioxidant effect, removes dead cells, and promotes wound healing.

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Drought stress is one of the most important climate-related factors affecting crop production. Tomatoes ( L.) are economically important crops which are highly sensitive to drought.

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In the face of growing global challenges in food security and increasing demand for sustainable protein sources, the aquaculture industry is undergoing a transformative shift through the integration of nanotechnology. This review paper explores the profound role of nanotechnology in aquaculture, addressing critical issues such as efficient feed utilization, disease management, and environmental sustainability. Nanomaterials are used to enhance nutritional content and digestibility of aquafeed, optimize fish growth and health, and improve disease prevention.

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Article Synopsis
  • Improving disease resistance in the animal and poultry industry may be enhanced through genetic selection for better immune systems, in addition to using drugs and vaccines.
  • A study on a 938 pedigreed population of Japanese quail examined various traits, including body weight and several organ weights, while analyzing immune response metrics like antibody levels and blood cell counts using advanced statistical models.
  • Results showed moderate heritability for immune traits, with potential for improving immune response by selecting for traits like spleen weight and higher IgG levels, which could enhance quail resistance to infections.
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Background And Aim: Tacrolimus (TAC) has significantly improved kidney graft survival following transplantation, though it is associated with adverse side effects. The most prevalent complication resulting from excessive TAC exposure is the onset of de novo diabetes mellitus (DM), a condition that can negatively impact both renal graft function and patient outcomes. De novo DM is linked to an increased risk of chronic transplant dysfunction, as well as cardiovascular morbidity and mortality.

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Despite various interventions to protect forests, many developing countries, including Ethiopia, continue to face substantial forest conservation challenges, particularly where local communities heavily rely on forests for their livelihoods. Recognizing the urgency of this issue, the government of Ethiopia introduced Participatory Forest Management (PFM) and devolved forest management responsibilities to enhance forest conservation. Therefore, this assessment examines the impacts of PFM on forest cover based on an analysis of the Land Use/Land Cover Change (LULCC) over the last 23 years in Adaba-Dodola, and its implications for REDD+ implementation.

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This is the first systematic review and meta-analysis of blue carbon stocks in Brazilian mangroves. We evaluated the effect of characteristics and site status (impacted versus non-impacted) on carbon stocks found in the various compartments on total ecosystem carbon stock (TECS). TECS followed an inverse trend with the latitudinal position: the highest values were found on the North coast (mean 511 Mg C ha), followed by the Northeast and Southeast.

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Nutrition may affect animal health due to the strong link between them. Also, diets improve the healing process in various disease states. Cancer is a disease, where the harmful consequences of tumors severely impair the body.

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As only 10% of the broiler breeder flock is roosters, their fertility is very important. The rooster sperm plasma membrane has high concentrations of polyunsaturated fatty acids that are sensitive to oxidative stress. Lipid peroxidation can change membrane structure, permeability, and fluidity, adversely affecting the acrosome reaction and fertility.

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Canine exfoliative cutaneous lupus erythematosus (ECLE) is the rarest variant of cutaneous lupus in dogs and has strong breed predilections. This report presents the clinical, histopathological and immunohistochemical features of two ECLE cases in mixed breed littermates and confirms the expected genetic mutation. A therapeutic response to oclacitinib also is documented.

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Metal-Based Drug-DNA Interactions and Analytical Determination Methods.

Molecules

September 2024

Department of Pharmaceutical Biochemistry and Clinical Laboratory, Faculty of Pharmacy, "Iuliu-Hațieganu" University of Medicine and Pharmacy, 400012 Cluj-Napoca, Romania.

Article Synopsis
  • * Binding mechanisms consist of covalent interactions (irreversible) like cross-linking, and non-covalent interactions (reversible) such as intercalation and groove binding.
  • * The review emphasizes DNA-metal complex interactions and outlines methods currently used to study these interactions.
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Repairing or reconstructing significant bone defects is typically challenging. In the present study, two composite cements were used as scaffolds in a sub-critical femoral defect in rats. A control group and two experimental batches were used to compare the outcomes.

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The present study aimed to investigate the effects of the ethanol extract (GPEE) on oxidative stress, inflammation, and metabolic markers in a rat model of streptozotocin-induced diabetes mellitus (DM). Phytochemical analysis using high-performance liquid chromatography coupled with mass spectrometry was performed to measure the total phenolic and flavonoid contents. In vitro antioxidant activity was evaluated through DPPH, FRAP, HO, and NO scavenging tests, and the in vivo effects of the GPEE were assessed in streptozotocin-induced DM rats.

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Aspen (Populus tremula L.) is a keystone species and a model system for forest tree genomics. We present an updated resource comprising a chromosome-scale assembly, population genetics and genomics data.

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Evolutionarily conserved core microbiota as an extended trait in nitrogen acquisition strategy of herbaceous species.

New Phytol

November 2024

Centre for Grassland Microbiome, State Key Laboratory of Grassland Agro-Ecosystems, College of Pastoral Agriculture Science and Technology, Lanzhou University, Lanzhou, 730020, China.

Microbiota have co-evolved with plants over millions of years and are intimately linked to plants, ranging from symbiosis to pathogenesis. However, our understanding of the existence of a shared core microbiota across phylogenetically diverse plants remains limited. A common garden field experiment was conducted to investigate the rhizosphere microbial communities of phylogenetically contrasting herbaceous families.

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Carotenoids, the natural pigments that confer the bright orange color of sea buckthorn berries, are also associated with several health benefits, such as antioxidant activity and skin and eye protection. Due to their lipophilic nature and localization, carotenoids are largely retained in the sea buckthorn pomace (SBP) resulting from juice production. Carotenoids from SBP (70.

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Phytochemical Composition Antioxidant and Anti-Inflammatory Activity of and .

Antioxidants (Basel)

August 2024

Department of Morpho-Functional Sciences, Discipline of Pathophysiology, Iuliu Haţieganu University of Medicine and Pharmacy, 400012 Cluj-Napoca, Romania.

This study aimed to investigate the antioxidant and anti-inflammatory activities mechanism of () and () ethanol extracts in acute rat inflammation induced in Wistar male rats with turpentine oil. The characterization of the polyphenolic compounds in the extracts was conducted using UV-Vis and Fourier-transform infrared spectroscopy and high-performance liquid chromatography coupled with mass spectrometry techniques. The antioxidant activity of the extracts was evaluated in vitro by DPPH, FRAP, HO, and NO scavenging tests and in vivo by measuring the total oxidative status (TOS), total antioxidant capacity (TAC), oxidative stress index (OSI), 8-hydroxy-deoxyguanosine (8-Oxo-dG), advanced oxidation protein products (AOPP), malondialdehyde (MDA), nitric oxide (NO), 3-nitrotyrosine (3NT), and total thiols (SH).

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