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Background: Takotsubo syndrome is an increasingly common cardiac emergency with no known evidence-based treatment.

Objectives: The purpose of this study was to investigate cardiovascular mortality and medication use after takotsubo syndrome.

Methods: In a case-control study, all patients with takotsubo syndrome in Scotland between 2010 and 2017 (n = 620) were age, sex, and geographically matched to individuals in the general population (1:4, n = 2,480) and contemporaneous patients with acute myocardial infarction (1:1, n = 620).

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