1 results match your criteria: "University of Aberdeen and Aberdeen Royal Hospitals Trust[Affiliation]"
Thiopurine methyltransferase genotype predicts therapy-limiting severe toxicity from azathioprine.
Ann Intern Med
November 1998
University of Aberdeen and Aberdeen Royal Hospitals Trust, United Kingdom.
Background: Substantial hematologic toxicity limits the use of azathioprine.
Objective: To evaluate 1) polymorphic inactivation of azathioprine by thiopurine methyltransferase and 2) clinical toxicity.
Design: Prospective cohort study.