3 results match your criteria: "University de Castilla-La Mancha[Affiliation]"
Effectiveness of Scalp Cooling to Prevent Chemotherapy-Induced Alopecia in Patients Undergoing Breast Cancer Treatment: A Systematic Review and Meta-analysis.
Cancer Nurs
June 2024
Author Affiliations: Health Research Department, University de Castilla La Mancha (Drs Álvarez Bueno, Cavero Redondo, and Jiménez López), Cuenca; and Servicio de Salud de Castilla-La Mancha (Mr Contreras Molina, Mrs Lucerón Lucas-Torres, and Mrs García Maestro), Albacete, Spain; Universidad Politécnica y Artística del Paraguay (Dr Álvarez Bueno), Asunción; and Facultad de Ciencias de la Salud, Universidad Autónoma de Chile (Dr Cavero Redondo), Talca.
Background: Chemotherapy-induced alopecia could cause significant psychological changes, affecting patients' quality of life and their capacity to cope with the disease.
Objectives: The aims of this study was to analyze the effectiveness of scalp cooling (SC) to prevent chemotherapy-induced alopecia in patients with breast cancer and to compare the use of automated versus nonautomated therapy delivery devices.
Methods: We searched the Cochrane Central Register of Controlled Trials, MEDLINE (through PubMed), Scopus, Web of Science, and ClinicalTrials.
Analysis of Ion Pairing in Solid State and Solution in -Cymene Ruthenium Complexes.
Inorg Chem
October 2020
University de Castilla-La Mancha, Departamento de Química Inorgánica, Orgánica y Bioquímica, CRIB, Fac. de Ciencias y Tecnologías Químicas, Avda. C. J. Cela, 10, 13071-Ciudad Real, Spain.
Article Synopsis
- The study highlights the significance of ion pairing in various chemistry fields and presents cationic-cymene ruthenium complexes with specific anion interactions.
- X-ray diffraction and DFT modeling reveal strong interactions between cations and anions, indicating unique molecular arrangements in both solid and solution states.
- Preliminary investigations suggest that the complexes exhibit cytotoxic effects on HeLa cell lines, potentially enhanced by specific structural elements like the lipophilic BPh anion and the NH group.
Nonaqueous capillary electrophoresis method for the analysis of gleevec and its main metabolite in human urine.
J Chromatogr A
March 2005
Department of Analytical Chemistry and Foods Technology, University de Castilla-La Mancha, Avenida Camilo Jose Cela 10, Ciudad Real 13071, Spain.
The viability of nonaqueous capillary electrophoresis (NACE) was investigated for determination of gleevec and its main metabolite in human urine using a fused-silica capillary. Baseline separation of the studied solutes was obtained using a nonaqueous solution composed of 12 mM ammonium acetate and 87.6 mM acetic acid in methanol-acetonitrile (ACN) (80:20, v:v) providing analysis time shorter than 3 min.
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