5 results match your criteria: "University University of Wisconsin[Affiliation]"
18F-florbetapir Positron Emission Tomography-determined Cerebral β-Amyloid Deposition and Neurocognitive Performance after Cardiac Surgery.
Anesthesiology
April 2018
From the Department of Anesthesiology (R.Y.K., T.B., M.B., N.T., M.F.N., J.P.M.), Department of Radiology (O.G.J., S.B.-N.), Department of Biostatistics and Bioinformatics (Y.-J.L., W.Q.), and the Department of Psychiatry and Behavioral Science (P.M.D.), Duke University, Durham, North Carolina. 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Background: Amyloid deposition is a potential contributor to postoperative cognitive dysfunction. The authors hypothesized that 6-week global cortical amyloid burden, determined by F-florbetapir positron emission tomography, would be greater in those patients manifesting cognitive dysfunction at 6 weeks postoperatively.
Methods: Amyloid deposition was evaluated in cardiac surgical patients at 6 weeks (n = 40) and 1 yr (n = 12); neurocognitive function was assessed at baseline (n = 40), 6 weeks (n = 37), 1 yr (n = 13), and 3 yr (n = 9).
From the Revolution to Embodiment: 25 Years of Cognitive Psychology.
Perspect Psychol Sci
September 2013
In 1988, the cognitive revolution had become institutionalized: Cognition was the manipulation of abstract symbols by rules. But, much like institutionalized political parties, some of the ideas were becoming stale. Where was action? Where was the self? How could cognition be smoothly integrated with emotions, with social psychology, with development, with clinical analyses? Around that time, thinkers in linguistics, philosophy, artificial intelligence, biology, and psychology were formulating the idea that just as overt behavior depends on the specifics of the body in action, so might cognition depend on the body.
View Article and Find Full Text PDFThe role of tandem acyl carrier protein domains in polyunsaturated fatty acid biosynthesis.
J Am Chem Soc
May 2008
Division of Pharmaceutical Sciences, University University of Wisconsin, Madison, Wisconsin 53705, USA.
Acyl carrier protein (ACP) plays an essential role in fatty acid and polyketide biosynthesis, and most of the fatty acid synthases (FASs) and polyketide synthases (PKSs) known to date are characterized with a single ACP for each cycle of chain elongation. Polyunsaturated fatty acid (PUFA) biosynthesis is catalyzed by the PUFA synthase, and all PUFA synthases known to date contain tandem ACPs (ranging from 5 to 9). Using the Pfa PUFA synthase from Shewanella japonica as a model system, we report here that these tandem ACPs are functionally equivalent regardless of their physical location within the PUFA synthase subunit, but the total number of ACPs controls the overall PUFA titer.
View Article and Find Full Text PDFCross-linguistic differences in emotionality of autobiographical memories were examined by eliciting memories of immigration from bilingual speakers. Forty-seven Russian-English bilinguals were asked to recount their immigration experiences in either Russian or English. Bilinguals used more emotion words when describing their immigration experiences in the second language (English) than in the first language (Russian).
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