Caseous mitral annulus calcification: A forgotten benign condition mimicking cardiac mass, a case report.

Key Clinical Message: Caseous mitral annulus calcification is a rare benign condition that can be misdiagnosed on echocardiography especially when it presents as a mass. This report highlights the contribution of cardiac MRI and computed tomography to the diagnosis through the case of a patient previously treated for breast cancer.

Abstract: We report the case of a patient, previously treated for breast cancer, in whom echocardiography suggested the diagnosis of a cardiac tumor due the presence of a mass on the posterior mitral annulus.

Adherence and barriers to Mediterranean diet in Tunisian patients with nonalcoholic fatty liver disease.

The burden of non alcoolic fatty liver disease (NAFLD) is globally increasing. While crucial for management, NAFLD patient adherence to the Mediterranean diet (MD) is underexplored, especially in Mediterranean countries such as Tunisia. A prospective study (Nov 2022-Feb 2023) supervised MD introduction by a nutritionist, evaluated adherence with MEDAS scores (≥10 for good compliance), and explored barriers to good adherence.

Clinical impact of multidrug-resistant bacterial infections in patients with cirrhosis.

Recently, the emergency of multidrug-resistant organisms (MDRO) has complicated the management of bacterial infections (BI) in cirrhosis. We aimed to assess their clinical impact on patients with decompensated cirrhosis. A retrospective study included consecutive cirrhotic patients hospitalized for acute decompensation (AD) between January 2010 and December 2019.

When a polyester mesh causes an enterocutaneous fistula, 30 years after its implantation.

Digestive fistula on mesh is an exceptional and late complication of hernioplasty. The type of mesh and its position are often implicated in its occurrence. Clinical presentation is multiform.

Thyroid hormone resistance syndrome caused by a novel mutation in the thyroid hormone receptor-beta gene (, GLU457LYS) treated with methimazole.

A 15-year-old girl presented with hyperactivity and behavior disorders. She had tachycardia and no goiter. Thyroid hormones were high and TSH normal.

Parsonage-Turner syndrome of the brachial plexus secondary to COVID-19 vaccine: A case report.

Parsonage-Turner syndrome (PTS) is a peripheral inflammatory neuropathy of unknown etiology. We present a rare case of a 50-year-old male patient with PTS post-COVID-19 BNT162b2 mRNA vaccine. Symptoms occurred 15 days after the second dose.

Eumycotic mycetoma involving the right foot: A new Tunisian case.

A Tunisian patient with painless swelling and discharging sinuses of the right foot was diagnosed with Eumycetoma after 1 year of evolution. Mycetoma is a neglected disease relatively rare in our country. An early and accurate diagnosis, based on histopathological and microbiological examinations, limits functional and esthetical damage.

Collision lung tumor associating typical carcinoid tumor to sclerosing hemangioma.

Collision tumors associating carcinoid tumor and sclerosing pneumocytoma have rarely been reported in the literature. The clinical presentation may be challenging especially in cases showing multiple and bilateral nodules. This case illustrates the association of both tumors diagnosed incidentally and illustrates a full spectrum of neuroendocrine lesions and sclerosing pneumocytoma.

Extra-gonadal mature teratoma: A case report of retroperitoneal location with a literature review.

Extra-gonadal mature teratoma is a benign tumor occurring rarely in adults. The retroperitoneal localization constitutes less than 4%. Treatment consists of surgical resection.

Acute lithiasis cholangitis in pregnant women: About three cases.

Acute lithiasis cholangitis is a rare non-obstetric emergency during pregnancy, which may threaten fetus and mother's life. It requires a codified management in order to avoid complications. In this current study, we aimed to report our center experience in the management of acute lithiasis cholangitis occurring in three pregnant women.

Unilateral pseudouveitis revealing a pancreatic neuroendocrine carcinoma: A case report.

Neuroendocrine tumors are a heterogeneous group of tumors with a wide range of malignant potential that tend to have a relative prolonged course. These tumors infrequently metastasize to the orbit. To the best of our knowledge, ocular metastases from pancreatic neuroendocrine tumors (PNETs) have never been reported in the literature.

Hyperparathyroidism: Unusual location of brown tumors.

Brown tumors (BTs) are due to a proliferation of multinucleated giant cells in osteolytic lesions. They complicate the course of hyperparathyroidism. Thanks to an early screening of bone metabolism disorders; BTs are nowadays rare bone manifestations.

Primitive pelvic bone hydatidosis: What an amazing extension.

Hydatidosis is an anthropozoonosis mainly encountered in pastoral areas. It mostly affects the liver, lung, and rarely the bone and the soft tissues. Skeletal involvement is usually secondary to visceral hydatidosis.

Radiculopathies caused by spontaneous pneumorrachis: Two case reports and review of literature.

Pneumorarchis is a rare condition of low back pain. It is usually asymptomatic and secondary to trauma. Spontaneous pneumorrachis is scarce.

Acute transverse myelitis revealing ankylosing spondylitis: A case report and literature review.

When faced with a patient with acute myelopathy, thorough investigations should be undertaken to determine the cause. Ankylosing spondylitis should be kept in mind as a possible cause.

Intra-articular hip neurofibromas in von Recklinghausen's disease.

Neurofibromatosis is a genetic disorder with osteo-articular manifestations. The intra-articular location of neurofibroma is scarce.

A rare cause of cyanosis: Congenital methemoglobinemia.

Congenital Methemoglobinemia is a rare condition that may mimic congenital heart diseases. There are two types of congenital Methemoglobinemia. The type I is usually benign.

Atypical osteomalacia mimicking radiological features of spondyloarthritis: Never judge a book by its cover.

Longstanding osteomalacia, by its proliferative enthesopathic changes, may mimic the advanced features of SpA. Despite the typical radiological findings, the lack of response to anti-TNF should encourage clinicians to reconsider the diagnosis.

An unusual and severe case of paclitaxel-induced hand-foot syndrome.

Although paclitaxel is known to cause mild skin toxicity, it may induce severe HFS requiring drug withdrawal. Patients with high disease burden might receive prolonged paclitaxel chemotherapy. Hence, a grade 2 toxicity would better indicate withdrawal of paclitaxel instead of suspension and rechallenge, to prevent such severe HFS requiring long-time recovery.

Unilateral laterothoracic exanthema in an adult.

Unilateral laterothoracic exanthema (ULE) is a benign self-limited condition that spontaneously resolves in a few weeks. Occurring mostly in childhood, although few rare cases in adults have been also reported. Diagnosis of ULE is clinical, and laboratory investigations are not required.

Spinal cord compression by extramedullary hematopoiesis in beta-thalassemia major.

Extramedullary hematopoiesis is a normal compensatory reaction that can affect the epidural space, leading to spinal cord compression syndrome. MRI is the imaging method of choice for diagnosis and monitoring. Treatment is still controversial.

A "happy ending" of mediastinal and abdominal lymphadenopathy associated with hepatosplenomegaly and pulmonary lesions.

Major diagnosis for mediastinal and abdominal lymphadenopathy is lymphoma and tuberculosis. Spontaneous remarkable evolution should discuss viral infection on the condition that no corticosteroids have been taken before as they could magically improve an authentic lymphoma. Trial of antituberculosis treatment that is used in some cases could lead to a misdiagnosis as the viral-infected patient can spontaneously heal as it is described in this case.

Is there a circadian rhythm of postural control and perception of the vertical?

Daytime activity is largely regulated by the day/night pattern. Various physiological and cognitive functions display a variation during the diurnal period, where individuals manage their balance, spatial orientation and consequently their perception of the vertical. However, findings concerning daytime changes of postural control quality remain contradictory, mainly due to methodogical considerations.

The stimulatory effect of the octadecaneuropeptide ODN on astroglial antioxidant enzyme systems is mediated through a GPCR.

Astroglial cells possess an array of cellular defense systems, including superoxide dismutase (SOD) and catalase antioxidant enzymes, to prevent damage caused by oxidative stress on the central nervous system. Astrocytes specifically synthesize and release endozepines, a family of regulatory peptides including the octadecaneuropeptide (ODN). ODN is the ligand of both central-type benzodiazepine receptors (CBR), and an adenylyl cyclase- and phospholipase C-coupled receptor.