Mepolizumab induced palmoplantar psoriasis: A case report.

Background: Atopic dermatitis and asthma are two diseases whose pathogenesis is largely attributable to the activation, at least in the initial stages, of T helper (Th)-2 Lymphocytes, the related cytokine axis, and B lymphocytes with antibody production. Psoriasis is conversely a pathology resulting from a recruitment of Th-17 and Th-1 lymphocytes, after an initial role of innate immunity. Mepolizumab is a humanized monoclonal antibody directed against interleukin (IL)-5, a central cytokine in the Th-2 axis, therefore involved in the pathogenesis of asthma.

New Challenges for Classical and Quantum Probability.

The discovery that any classical random variable with all moments gives rise to a full quantum theory (that in the Gaussian and Poisson cases coincides with the usual one) implies that a quantum-type formalism will enter into practically all applications of classical probability and statistics. The new challenge consists in finding the classical interpretation, for different types of classical contexts, of typical quantum notions such as entanglement, normal order, equilibrium states, etc. As an example, every classical symmetric random variable has a canonically associated conjugate momentum.

MRI, US or real-time virtual sonography in the evaluation of adenomyosis?

Purpose: Real-time virtual sonography (RVS) allows displaying and synchronizing real-time US and multiplanar reconstruction of MRI images. The purpose of this study was to evaluate the feasibility and ability of RVS to assess adenomyosis since literature shows US itself has a reduced diagnostic accuracy compared to MRI.

Materials And Methods: This study was conducted over a 4-month period (March-June 2015).