42 results match your criteria: "University Polytechnique Hauts-de-France[Affiliation]"

This article describes an approach to making highly stable copper nanowire networks on any type of substrates. These nanostructured materials are highly sought after for, among other applications, the development of next-generation flexible electronics. Their high susceptibility to oxidation in air currently limits their use in the real world.

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Evaluation of the Impact of Infusion Set Design on the Particulate Load Induced by Vancomycin-Piperacillin/Tazobactam Incompatibility.

Pharmaceuticals (Basel)

September 2024

University of Lille, CHU Lille, ULR 7365-GRITA-Groupe de Recherche sur les formes Injectables et les Technologies Associées, F-59000 Lille, France.

Introduction: Drug incompatibilities are among the most common medication errors in intensive care units. A precipitate can form and block the catheter or cause an adverse event in the patient. Intensive care units have implemented various strategies for limiting the occurrence of these incompatibilities, which have already been studied in vitro under standardized conditions.

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Semiconductor nanowires (NWs) are believed to play a crucial role for future applications in electronics, spintronics and quantum technologies. A potential candidate is HgTe but its sensitivity to nanofabrication processes restrain its development. A way to circumvent this obstacle is the selective area growth technique.

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Coaches often use pointing gestures alongside their speech to reinforce their message and emphasize important concepts during instructional communications, but the impact of simultaneous pointing gestures and speech on learners' recall remains unclear. We used eye-tracking and recalled performance to investigate the impact of a coach's variously timed pointing gestures and speech on two groups of learners' (novices and experts) visual attention and recall of tactical instructions. Participants were 96 basketball players (48 novice and 48 expert) who attempted to recall instructions about the evolution of a basketball game system under two teaching conditions: speech accompanied by gestures and speech followed by gestures.

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Short-time expansion of one-dimensional Fokker-Planck equations with heterogeneous diffusion.

Phys Rev E

June 2024

University of Lille, Unité de Glycobiologie Structurale et Fonctionnelle (UGSF), CNRS UMR8576, F-59000 Lille, France.

We formulate a short-time expansion for one-dimensional Fokker-Planck equations with spatially dependent diffusion coefficients, derived from stochastic processes with Gaussian white noise, for general values of the discretization parameter 0≤α≤1 of the stochastic integral. The kernel of the Fokker-Planck equation (the propagator) can be expressed as a product of a singular and a regular term. While the singular term can be given in closed form, the regular term can be computed from a Taylor expansion whose coefficients obey simple ordinary differential equations.

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Increasing quantum confinement in semiconductor quantum dot (QD) systems is essential to perform robust simulations of many-body physics. By combining molecular beam epitaxy and lithographic techniques, we developed an approach consisting of a twofold selective area growth to build QD chains. Starting from 15 nm-thick and 65 nm-wide in-plane InGaAs nanowires on InP substrates, linear arrays of InGaAs QDs were grown on top, with tunable lengths and separations.

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Trpv6 channel targeting using monoclonal antibody induces prostate cancer cell apoptosis and tumor regression.

Cell Death Dis

June 2024

Department of Biology, Laboratory of Cell Physiology, INSERM U1003, Laboratory of Excellence Ion Channels Science and Therapeutics, Faculty of Science and Technologies, University of Lille, 59650, Villeneuve d'Ascq, France.

TRPV6 calcium channel is a prospective target in prostate cancer (PCa) since it is not expressed in healthy prostate while its expression increases during cancer progression. Despite the role of TRPV6 in PCa cell survival and apoptotic resistance has been already established, no reliable tool to target TRPV6 channel in vivo and thus to reduce tumor burden is known to date. Here we report the generation of mouse monoclonal antibody mAb82 raised against extracellular epitope of the pore region of the channel.

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Silver nanoparticles (Ag NPs) have been produced by low-dose (1-20 kGy) gamma irradiation of silver nitrate in the presence of graphene-based material (graphene oxide or electrochemically exfoliated graphene). The large surface area of those graphene-based materials combined with the presence of oxygen-containing functional groups on the surface provided successful nucleation and growth of Ag nanoparticles, which resulted in a uniformly covered graphene surface. The obtained Ag nanoparticles were spherical with a predominant size distribution of 10-50 nm for graphene oxide and 10-100 nm for electrochemically exfoliated graphene.

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Two 3D Fractal-Based Approaches for Topographical Characterization: Richardson Patchwork versus Sdr.

Materials (Basel)

May 2024

CNRS, UMR 8201-LAMIH-Laboratoire d'Automatique de Mécanique et d'Informatique Industrielles et Humaines, University Polytechnique Hauts-de-France, F-59313 Valenciennes, France.

Various methods exist for multiscale characterization of surface topographies, each offering unique insights and applications. The study focuses on fractal-based approaches, distinguishing themselves by leveraging fractals to analyze surface complexity. Specifically, the Richardson Patchwork method, used in the ASME B46.

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The field of bone tissue engineering is steadily being improved by novel experimental approaches. Nevertheless, microbial adhesion after scaffold implantation remains a limitation that could lead to the impairment of the regeneration process, or scaffold rejection. The present study introduces a methodology that employs laser-based strategies for the development of antimicrobial interfaces on tricalcium phosphate-hydroxyapatite (TCP-HA) scaffolds.

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Despite its high-level of robustness and versatility, the human sensorimotor control system regularly encounters and manages various noises, non-linearities, uncertainties, redundancies, and delays. These delays, which are critical to biomechanical stability, occur in various parts of the system and include sensory, signal transmission, CNS processing, as well as muscle activation delays. Despite the relevance of accurate estimation and prediction of the various time delays, the current literature reflects major discrepancy with regards to existing prediction and estimation methods.

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The mechanical properties of natural and man-made fibres ultimately govern the robustness of products. Examples range from textiles to composite materials for mechanical parts in emerging technological applications. An accurate determination of the mechanical properties of microscopic single fibres is therefore important.

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Improvement of Metal-Doped β-TCP Scaffolds for Active Bone Substitutes via Ultra-Short Laser Structuring.

Bioengineering (Basel)

December 2023

Laboratory of Micro and Nano-Photonics, Institute of Electronics, Bulgarian Academy of Sciences, 72 Tsarigradsko Chaussee Blvd, 1784 Sofia, Bulgaria.

Various efforts have been made to develop antibacterial biomaterials capable of also sustaining bone remodulation to be used as bone substitutes and reduce patient infection rates and related costs. In this work, beta-tricalcium phosphate (β-TCP) was chosen due to its known biocompatibility and use as a bone substitute. Metal dopants were incorporated into the crystal structure of the β-TCP, and disks were produced from this material.

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ProNGF promotes brain metastasis through TrkA/EphA2 induced Src activation in triple negative breast cancer cells.

Exp Hematol Oncol

December 2023

UMR9020-U1277 - CANTHER - Cancer Heterogeneity Plasticity and Resistance to Therapies, University of Lille, CNRS, Inserm, CHU Lille, Boulevard du Professeur Jules Leclercq, 59000, Lille, France.

Background: Triple-Negative Breast Cancer is particularly aggressive, and its metastasis to the brain has a significant psychological impact on patients' quality of life, in addition to reducing survival. The development of brain metastases is particularly harmful in triple-negative breast cancer (TNBC). To date, the mechanisms that induce brain metastasis in TNBC are poorly understood.

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Raman spectroscopy is well-suited for the characterization of semiconductor materials. However, due the weakness of the Raman signal, the studies of thin semiconductor layers in complex environments, such as ultrahigh vacuum, are rather scarce. Here, we have designed a Raman apparatus based on the use of a fiber optic probe, with a lens collecting the backscattered light directly inserted in ultrahigh vacuum.

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Background: Cardiovascular diseases (CVDs), being the culprit for one-third of deaths globally, constitute a challenge for biomedical instrumentation development, especially for early disease detection. Pulsating arterial blood flow, providing access to cardiac-related parameters, involves the whole body. Unobtrusive and continuous acquisition of electrical bioimpedance (EBI) and photoplethysmography (PPG) constitute important techniques for monitoring the peripheral arteries, requiring novel approaches and clever means.

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Personality is considered as the internal factor that defines a person's behavior. Therefore, providing adaptive features and personalized support in online learning by considering learners' personalities can improve their learning experiences and outcomes. In this context, several research studies have investigated the impact of personality differences in online learning.

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Improvement of insulin secretion by pancreatic β-cells and preservation of their mass are the current challenges that future antidiabetic drugs should meet for achieving efficient and long-term glycemic control in patients with type 2 diabetes (T2D). The successful development of glucagon-like peptide 1 (GLP-1) analogues, derived from the saliva of a lizard from the family, has provided the proof of concept that antidiabetic drugs directly targeting pancreatic β-cells can emerge from venomous animals. The literature reporting on the antidiabetic effects of medicinal plants suggests that they contain some promising active substances such as polyphenols and alkaloids, which could be active as insulin secretagogues and β-cell protectors.

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Neuro mechanical time delay is inevitable in the sensorimotor control of the body due to sensory, transmission, signal processing and muscle activation delays. In essence, time delay reduces stabilization efficiency, leading to system instability (e.g.

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A Multiscale Topographical Surface Analysis of High Entropy Alloys Coatings by Laser Melting.

Materials (Basel)

January 2023

Bruker Nano Surface Division, 7 rue de la croix Martre, 91120 Palaiseaux, France.

High Entropy Alloys (HEAs) coatings obtained by laser melting (LM) technique were studied through a multiscale topographical surface analysis using a focus variation microscope. The laser melting creates a multiscale topography from under-powder size (incomplete or complete powder melting) to upper-powder size (process conditions). The surface topography must be optimized because of the significant influence on friction and material transfer during sliding wear.

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Microfabricated chip-edge microcantilevers are commonly used as surface probes, e.g. in near-field microscopy.

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To characterize various induced phenomena and the blood of healthy sheep using several parameters, the evaporation dynamics of 72 drops of sheep blood evaporated at several temperatures: 23, 37, 60, and 90 °C on glass hydrophilic substrates were studied. This allows the prediction of the sheep blood pattern, knowing the surface temperature and vice versa. To determine the variation in the Marangoni number between the center and the triple line, an infrared thermography method was used to measure the temperature variation along the surface of the drop.

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In the ultrasonic non-destructive evaluation of thin films, it is essential to have ultrasonic transducers that are able to generate surface acoustic waves (SAW) of suitably high frequencies in a wide frequency range of between ten and several hundred megahertz. If the characterization is carried out with the transducer in contact with the sample, it is also necessary that the transducers provide a high level of mechanical displacement (>100 s pm). This level allows the wave to cross the transducer−sample interface and propagate over the distance of a few millimeters on the sample and be properly detected.

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Novel cyano-benzylidene xanthene derivatives were synthesized using one-pot and condensation reactions. A diprotic Brønsted acid (i.e.

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