145 results match your criteria: "University Policlinic[Affiliation]"

Objective: Dental professionals are highly vulnerable to work-related musculoskeletal disorders (WMSD). As females, who are more prone to WMSD, represent a growing proportion of the dental workforce, this study explored sex differences in WMSD-pain prevalence among dental students, and differentiated it between preclinical and clinical students.

Methods: A multi-center cross-sectional study was conducted among dental students at three U.

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The aim of this study was to elucidate the impact of porcine pancreatic enzymes (Creon pancrelipase) in comparison to microbial-derived alpha amylase (MD amylase) on the small intestine wall structure, mucosal glycogen accumulation, and enterocyte turnover. The impact of enzyme supplementation on the small intestine was explored in 18 pigs with surgically induced exocrine pancreatic insufficiency (EPI). Four healthy pigs served as the control group.

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Background: The possible existence of an acini-islet-acinar (AIA) reflex, involving mutual amylase and insulin interactions, was investigated in the current acute experiment on pigs.

Aim: To confirm the existence of an AIA reflex and justify the placement of the exocrine and endocrine pancreatic components within the same organ.

Methods: The study was performed on six pigs under general anesthesia.

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Introduction: Dental sleep medicine is an emerging field within dentistry. While limited education in sleep medicine has been reported among US predoctoral dental schools, no study has been conducted among postgraduate dental programs. This study compared the extent and exposure to sleep medicine education among US postgraduate programs in orthodontics, pediatric dentistry, orofacial pain (OFP), general practice residency (GPR), and advanced education in general dentistry (AEGD).

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For a long time, the study of heart failure focused on single heart chamber disease. There is, instead, growing attention on the interplay between the atria and the ventricles during the cardiac cycle and on the consequences of an altered chamber coupling on global heart performance and heart failure. This review aimed to explore the principles of atrioventricular (AV) function and coupling of the left heart and the consequences that their disruption could have in several diseases.

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Introduction: The aging of the population requires an appropriate knowledge of the type of care that needs to be provided to inform healthcare policies. In Italy, neither home care nursing, nor the patient experiences have ever been described.

Objectives: To describe the characteristics of nurses and care recipients involved in home care.

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Article Synopsis
  • The study investigates the effects of lurasidone, an atypical antipsychotic, on individuals with schizophrenia spectrum disorder and coexisting alcohol/substance use disorders (AUD/SUD).
  • Results showed significant reductions in psychological symptoms, cravings for substances, and aggressiveness, as well as improvements in overall quality of life after one month of treatment.
  • Lurasidone demonstrated good tolerability, with only a small percentage of participants discontinuing due to side effects, highlighting its potential for effective treatment in dual diagnosis cases.
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Impact of Concurrent Use of N95 and Surgical Masks on Peripheral Oxygen Saturation and Heart Rate Frequency-A Prospective Study during the COVID-19 Outbreak.

Medicina (Kaunas)

February 2024

Department of Dental Clinic and Maxillofacial Surgery, A. Gemelli University Policlinic IRCCS, Catholic University of Sacred Heart, Largo Francesco Vito 1, 00168 Rome, Italy.

: The COVID-19 outbreak has necessitated the prolonged use of N95 facemasks in addition to traditional surgical facemasks by healthcare workers. The aim of this study was to investigate the effect of wearing N95 facemasks in addition to surgical facemasks on peripheral oxygen saturation (SpO) and heart rate (HR) among dental professionals during routine care. : This prospective study compared SpO and HR between dental providers wearing N95 + surgical facemasks vs.

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Relationship between insomnia and pain in patients with chronic orofacial pain.

Pain Med

May 2024

Division of Orofacial Pain, Department of Oral Health Science, University of Kentucky, College of Dentistry, Lexington, KY 40536, United States.

Objective: Few studies have investigated specific associations between insomnia and orofacial pain (OFP). The aim of this cross-sectional study was to examine relationships of insomnia with pain, mental health, and physical health variables among treatment-seeking patients with chronic OFP.

Methods: OFP diagnosis, demographics, insomnia symptoms, pain intensity, interference, and duration, mental health measures, and number of medical comorbidities were extracted from the medical records of 450 patients receiving an initial appointment at a university-affiliated tertiary OFP clinic.

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The acini-islet-acinar (AIA) axis concept justifies the anatomical placement of the Langerhans islets within the exocrine pancreatic parenchyma and explains the existence of the pancreas as a single organ. Amylase has been suggested to play a key role as an anti-incretin factor. Oral glucose tolerance tests (OGTT) were performed on 18 piglets in both a healthy (prior to pancreatic duct ligation (PDL) surgery, study Day 10) and an exocrine pancreatic insufficient (EPI) state (30 days after PDL, study Day 48)).

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Article Synopsis
  • - This article reviews various models and clinical challenges related to using accelerated diagnostic protocols involving cardiac biomarkers for patients with acute cardiac symptoms in the emergency department (ED).
  • - Key topics include the interpretation of high-sensitivity cardiac troponin levels, the significance of biomarker variations in severe patients, the benefits of point-of-care testing for early diagnosis, and the role of biomarkers in acute heart failure cases.
  • - Emphasizing the balance between timely discharge and comprehensive cardiac assessment, the article advocates for using specific biomarkers to improve early detection of heart issues, reduce hospitalization time, and predict patient outcomes while calling for collaborative studies on diagnostic protocols.
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Article Synopsis
  • Heart failure (HF) is a condition where the heart doesn't work well, and it affects other organs, especially the liver, making it a serious illness.
  • The article looks at how problems in the heart can lead to liver issues, and how tests like liver stiffness measurement (LSM) can help doctors understand and treat this connection.
  • Researchers are studying different tests and scores based on liver health to see how well they can predict problems for HF patients, but more research is needed to see how these tests work together.
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: A higher prevalence of dental malocclusion has been suggested among individuals with Down Syndrome (DS) compared to controls, although no studies to date have investigated such a difference according to age group. Therefore, the aim of this study was to compare the prevalence of dental malocclusion and other orthodontic measures between DS and non-syndromic (non-DS) individuals across three age groups of children, adolescents, and adults. : This cross-sectional study was conducted on a total of 147 patients.

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Objectives: The aim of Working Group 4 was to address patient benefits associated with implant dentistry. Focused questions on (a) dental patient-reported outcomes (dPROs), (b) improvement in orofacial function, and (c) preservation of orofacial tissues in partially and fully edentulous patients following provision of implant-retained/supported dental prostheses were addressed.

Materials And Methods: Three systematic reviews formed the basis for discussion.

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Obstructive sleep apnea treatment improves temporomandibular disorder pain.

Sleep Breath

March 2024

Department of Dental Clinic and Maxillofacial Surgery, A. Gemelli University Policlinic IRCCS, Catholic University of Sacred Heart, Largo Agostino Gemelli 1, 00168, Rome, Italy.

Purpose: The existence of a bidirectional relationship between poor sleep and pain intensity has been studied, and good sleep quality has been found to be a key factor underlying pain control. The purpose of this prospective cohort study was to observe if OSA treatment provides a reduction in temporo-mandibular disorder (TMD) pain and headache attributed to TMD in patients with obstructive sleep apnea (OSA) after 18 months of OSA treatment.

Methods: A prospective cohort study was conducted on consecutive patients suffering from OSA.

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Objectives: To test whether soft tissue volume augmentation using a collagen matrix (VCMX) leads to noninferior results in terms of gain of mucosal thickness at single implant sites, compared to connective tissue grafts (SCTG).

Methods: The study was designed as a multi-center randomized controlled clinical trial. Subjects in need of soft tissue volume augmentation at single tooth implant sites were consecutively recruited at nine centers.

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Importance: Ileocolic intussusception is an important cause of intestinal obstruction in children. Reduction of ileocolic intussusception using air or fluid enema is the standard of care. This likely distressing procedure is usually performed without sedation or analgesia, but practice variation exists.

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Effectiveness of dental monitoring system in orthodontics: A systematic review.

J Orthod

March 2024

Dental School, Department of Medical and Surgical Specialties, Radiological Sciences and Public Health, University of Brescia, Brescia, Italy.

Background: Dental monitoring (DM) constitutes a recent technological advance for the remote monitoring of patients undergoing an orthodontic therapy. Especially in times of health emergency crisis, the possibility of relying on remote monitoring could be particularly useful.

Objectives: To assess the effectiveness of DM in orthodontic care.

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Introduction: Considering the increasing complexity of care and workload for home care nurses due to the ageing of the population, it is crucial to describe the work environment and the community care setting. The aim of this study protocol is to map the characteristics and identify gaps of home care in the community to design future interventions aimed at ensuring quality and safety.

Methods And Analysis: This is a national cross-sectional descriptive observational study using the survey method.

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: New era of cardiac surgery aims to provide an enhanced postoperative recovery through the implementation of every step of the process. Thus, perfusion strategy should adopt evidence-based measures to reduce the impact of cardiopulmonary bypass (CPB). Hematic Antegrade Repriming (HAR) provides a standardized procedure combining several measures to reduce haemodilutional priming to 300 mL.

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The Notch pathway is an evolutionarily preserved signaling pathway involved in a variety of vital cell functions. Additionally, it is one of the key regulators of inflammation, and controls the differentiation and function of different cells. Moreover, it was found to be involved in skeletal development and bone remodeling process.

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Chronic lymphocytic leukemia (CLL) is the most common form of adult leukemia in the western world. In Italy, venetoclax was approved for use in patients with CLL as monotherapy in 2017 and in combinations in 2019. As a result of this delayed approval, there are relatively few real-world studies from Italian clinical practice and much of the data are in heavily pretreated patients.

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