Effect of co-administration of gallic acid and quercetin or gallic acid and rutin on impaired spermatogenesis and oxidative damage in a busulfan-treated rat model.

Gallic acid (GAL), rutin (RUT), and quercetin (QUE) are common antioxidant agents in fruits and vegetables with intriguing pharmacological effects. In the present study, we compared the therapeutic outcomes of GAL + QUE in comparison with GAL + RUT co-treatment in a busulfan (BUS) model of testicular injury in Wistar rats. BUS (4 mg kg body weight (b.

Stroke Survivors' Interaction With Hand Rehabilitation Devices: Observational Study.

Background: The hand is crucial for carrying out activities of daily living as well as social interaction. Functional use of the upper limb is affected in up to 55% to 75% of stroke survivors 3 to 6 months after stroke. Rehabilitation can help restore function, and several rehabilitation devices have been designed to improve hand function.

Addressing the Global Burden of Cardiovascular Disease in Women: JACC State-of-the-Art Review.

Cardiovascular diseases (CVDs) are responsible for approximately 35% of all deaths in women. In 2019, the global age-standardized CVD prevalence and mortality of women were 6,403 per 100,000 and 204 per 100,000, respectively. Although the age- and population-adjusted prevalence has decreased globally, opposite trends are evident in regions of socioeconomic deprivation.

Assessing desertification vulnerability and mitigation strategies in northern Nigeria: A comprehensive approach.

Desertification constitutes a grave threat to the environmental and socio-economic stability of desertification frontline states in Northern Nigeria. From 2003 to 2020, this research comprehensively analyzes desertification vulnerability, integrating parameters such as NDVI, LST, TVDI, MSAVI, and Albedo. Key factors contributing to land degradation are identified, along with the spatial patterns and trends of desertification over the two-decade period.

Groundwater in the coastal areas of Ghana: Quality and associated health risks.

Self-supply water sources, particularly groundwater sources, play key roles in the water supply ecosystem of developing countries. Recent studies indicate that groundwater sources in coastal communities in Ghana are under threat from improper waste management practices, seawater intrusion and atmospheric aerosol deposition. In this study, Water Quality Index (WQI) and Nemerow's Pollution Index (NPI) were employed to assess groundwater quality in four coastal communities of Ghana.

Medium-chain carboxylates production from plant waste: kinetic study and effect of an enriched microbiome.

Background: The need for addition of external electron donors such as ethanol or lactate impairs the economic viability of chain elongation (CE) processes for the production of medium-chain carboxylates (MCC). However, using feedstocks with inherent electron donors such as silages of waste biomass can improve the economics. Moreover, the use of an appropriate inoculum is critical to the overall efficiency of the CE process, as the production of a desired MCC can significantly be influenced by the presence or absence of specific microorganisms and their metabolic interactions.

Impact of Covid-19 on Residency Training in Tertiary Health Institutions in Nigeria: A National Survey.

Background: The emergence of COVID-19 had a massive impact on the health system globally. While there are many kinds of literature reporting the impact on postgraduate medical training in other parts of the world, this cannot be said about Nigeria.

Methodology: This was a national cross-sectional study among Resident doctors via an online google form survey for 8-months.

Determinants of effective interventions for HIV prevention, treatment, and care to address inequitable HIV outcomes among Black Women of African Descent (BWAD) in High-Income Countries: Systematic review protocol.

Background: In High-Income Countries (HICs) HIV/AIDS continues to disproportionally affect Black Women of African Descent (BWAD) and other racialized groups and is now a major public health concern. Despite the multiple efforts, evidence is limited on the effectiveness of HIV interventions to address the HIV outcomes inequalities among BWAD. This protocol outlines the methodological process of a systematic review that will gather quantitative and qualitative data to examine existing determinants of effective HIV prevention, treatment, and care interventions to address the HIV outcomes disparities and inequities among BWAD in HICs.

Maternal morbidity and death associated with pregnancy loss before 28 weeks in Nigeria.

Objective: To determine the prevalence of maternal morbidity and death from pregnancy loss before 28 weeks in referral-level hospitals in Nigeria.

Design: Secondary analysis of a nationwide cross-sectional study.

Setting: Fifty-four referral-level hospitals.

Neonatal jaundice incidence, risk factors and outcomes in referral-level facilities in Nigeria.

Objective: To determine the incidence, risk factors and outcomes of babies with neonatal jaundice in a network of referral-level hospitals in Nigeria.

Design: A cross-sectional analysis of perinatal data collected over a 1-year period.

Setting: Fifty-four referral-level hospitals (48 public and 6 private) across the six geopolitical zones of Nigeria.

Advancing noise management in aviation: Strategic approaches for preventing noise-induced hearing loss.

As urbanization and population growth escalate, the challenge of noise pollution intensifies, particularly within the aviation industry. This review examines current insights into noise-induced hearing loss (NIHL) in aviation, highlighting the risks to pilots, cabin crew, aircraft maintenance engineers, and ground staff from continuous exposure to high-level noise. It evaluates existing noise management and hearing conservation strategies, identifying key obstacles and exploring new technological solutions.

Spatiotemporal and seasonal transmission dynamics of and snail infectivity in Ase River catchment, Delta State, Nigeria.

are intermediate snail hosts of . Despite their vectorial role, the transmission dynamics and infectivity of these intermediate snail hosts remain understudied in the Ase River. This longitudinal study evaluated the geospatial and seasonal transmission patterns and infectivity of three vectors between November 2020 and October 2022 in the Ase River catchment, Delta State, Nigeria.

Transforming adolescent menstrual health through policy: the role of value added tax exemptions in improving access to sanitary products.

In Namibia, the Value Added Tax (VAT) Amendment Act 2022, which reclassified the supply of sanitary pads as zero-rated, has significant implications for adolescent girls' menstrual health and education. The policy change responds to the need to address period poverty by making essential menstrual products more accessible and affordable. Menstruation is a normal biological process, and access to sanitary products is a human right.

Gas flaring: technicalities, challenges, and the economic potentials.

Gas flaring has been identified as a major contributor to global warming and climate change. It is used either as a safety measure or as a means of disposal for technical or economic reasons. Over 250 toxins have been directly/indirectly associated with gas flaring and its associated emissions.

Individual-level Predictors of Birth Preparedness and Complication Readiness: Urban-Rural Comparison.

Introduction: Maternal mortality is a major public health problem. Birth preparedness and complication readiness (BP/CR) constitute a veritable strategy for reducing maternal mortality, yet adoption is low with wide urban-rural discrepancies.

Objectives: The objectives of this study were to compare the practice of BP/CR amongst women in rural and urban areas of Rivers State, Nigeria, and determine the individual-level predictors.

Compliance and adherence to hand hygiene practices for effective infection control.

Hand hygiene (HH) is the most effective way to curb the spread of healthcare-associated infections. Nonetheless, healthcare personnel encounter difficulties in adhering to WHO HH recommendations. This study aimed to investigate HH compliance and adherence after the implementation of an action plan in a municipal hospital in Moscow.

COVID-19 Vaccination Rates and Predictors of Vaccine Uptake Among Adults With Chronic Obstructive Pulmonary Disease: Insights From the 2022 National Health Interview Survey.

Background and objective The coronavirus disease 2019 (COVID-19) vaccination rates and predictors of vaccine uptake among patients with chronic obstructive pulmonary disease (COPD) in the United States are unknown. In light of this, we assessed COVID-19 vaccination rates in this population and evaluated predictors of vaccine uptake. Methods Using 2022 survey data from the National Health Interview Survey (NHIS), 1486 adults with COPD who responded with "yes/no" to whether they had received the COVID-19 vaccine were identified, including those who had received booster doses.

Current state of minimally invasive general surgical practice in Africa: A systematic review and meta-analysis of the laparoscopic procedures performed and outcomes.

Background: Minimally invasive surgery, including laparoscopy and robotics, has significantly improved general surgical (GS) practice globally. While robot-assisted GS practice is yet to be adopted in the majority of Africa, laparoscopy has been utilized to improve surgical outcomes. This study aims to review the laparoscopic GS procedures (LGSPs) performed and evaluate outcomes such as conversion to open surgery, morbidity, and mortality in Africa.

Geo-mechanical and geo-morphology characterisation of the cap rocks in the Niger Delta for potential carbon capture and storage.

The world has been battling climate change which is caused by an excessive amount of carbon dioxide in the atmosphere. Carbon sequestration in geological sinks was identified as one of the major methods to curb and reduce the amount of carbon dioxide in the atmosphere. The carbon dioxide stored in the geological formations must not escape back into the atmosphere.

Effect of neoadjuvant therapy regimens on lymph nodes yield in rectal cancer.

Background And Objectives: Pathological nodal staging is relevant to postoperative decision-making and a prognostic marker of cancer survival. This study aimed to assess the effect of different total neoadjuvant therapy (TNT) regimens on lymph node status following total mesorectal excision (TME) for locally advanced rectal cancer (LARC).

Methods: A retrospective cohort study of patients treated for node-positive clinical stage 3 LARC with TNT between January 2015 and August 2022.

Assessment of Liver Antioxidant Profile in Infected Mice Treated with Curative Ethanol Leaf extract of .

Background: The increasing resistance to most antimalarial drugs suggests a need for better alternatives. This study evaluated in vivo antimalarial and liver antioxidant profile of dry plantain leaf extract (Musa paradisiaca) on mice infected with Plasmodium berghei.

Methods: Six groups of ten mice each grouped as control, P.

Cabo Verde's malaria-free certification: A blueprint for eradicating malaria in Africa.

The World Health Organisation (WHO) officially certified Cabo Verde as a malaria-free country in January 2024, marking a key milestone in world health and demonstrating the efficacy of comprehensive malaria control programs. Cabo Verde is only the third country in the WHO African region to have achieved this designation, highlighting the potential for other nations to successfully eradicate malaria. Despite encountering hurdles like drug-resistant strains and COVID-19 disruptions, Cabo Verde's success after years of strategic planning and multisectoral collaboration highlights the value of long-term public health initiatives.