Medication stewardship in the operating theatre in Malaysia: A quality improvement project.

Background And Aims: A quality improvement project ('Safe Anaesthesia for ALL-SEAL') was implemented to reduce preventable medication errors and drug wastage in the operating theatre (OT) of a tertiary hospital. The primary objective of this quality improvement project was to prevent the incidence of medication errors, and the secondary objective was to reduce the wastage of unused drugs.

Methods: A pre-intervention questionnaire and an audit survey were performed, and multidirectional interventions were designed post-survey.

Acquisition and evolution of the neurotoxin domoic acid biosynthesis gene cluster in Pseudo-nitzschia species.

Of the hitherto over 60 taxonomically identified species in the genus of Pseudo-nitzschia, 26 have been confirmed to be toxigenic. Nevertheless, the acquisition and evolution of the toxin biosynthesis (dab) genes by this extensive group of Pseudo-nitzschia species remains unclear. Through constructing chromosome-level genomes of three Pseudo-nitzschia species and draft genomes of ten additional Pseudo-nitzschia species, putative genomic integration sites for the dab genes in Pseudo-nitzschia species were explored.

Epigenetic changes driven by environmental pollutants in lung carcinogenesis: a comprehensive review.

Lung cancer remains the leading cause of cancer-related mortality globally, with environmental pollutants identified as significant risk factors, especially for nonsmokers. The intersection of these pollutants with epigenetic mechanisms has emerged as a critical area of interest for understanding the etiology and progression of lung cancer. Epigenetic changes, including DNA methylation, histone modifications, and non-coding RNAs, can induce alterations in gene expression without affecting the DNA sequence and are influenced by environmental factors, contributing to the transformation of normal cells into malignant cells.

Reaching machine learning leverage to advance performance of electrocatalytic CO conversion in non-aqueous deep eutectic electrolytes.

Deep eutectic electrolytes (DEEs) show promise for future electrochemical systems due to their adjustable buffer capacities. This study utilizes machine learning algorithms to analyse the carbon dioxide reduction reaction (CORR) in DEEs with a buffer capacity of approximately 10.21 mol/pH.

The effect of recreational therapy application on fatigue in hemodialysis patients: a randomized clinical trial.

Background: Chronic Kidney Disease (CKD) is a progressive disorder that often leads to End-Stage Renal Disease (ESRD), necessitating hemodialysis (HD) treatment. Fatigue is a prevalent and debilitating symptom among HD patients, significantly affecting their quality of life. Recreational Therapy (RT) is a therapeutic recreational service designed to maintain and restore a person's level of performance and independence in daily activities.

Benzofurans and dibenzofurans from galls on twigs of the endangered Chinese endemic tree Parrotia subaequalis and their inhibitory properties against Staphylococcus aureus and ATP-citrate lyase.

Parrotia subaequalis, an endangered Tertiary relict tree native to China and a member of the Hamamelidaceae family, is one of several host plant species in this family that exhibit unique ecological habits, such as gall formation. Tree galls are the results of complex interactions between gall-inducing insects and their host plant organs. The formation of galls may serve to protect other regions of the plant from potential damage, often through the production of phytoalexins.

Pyridine and Pyrimidine hybrids as privileged scaffolds in antimalarial drug discovery: A recent development.

Malaria continues to pose a significant threat to global health, which is exacerbated by the emergence of drug-resistant strains, necessitating the urgent development of new therapeutic options. Due to their substantial bioactivity in treating malaria, pyridine and pyrimidine have become the focal point of drug research. Hybrids of pyridine and pyrimidine offer a novel and promising avenue for developing effective antimalarial agents.

Design of agricultural question answering information extraction method based on improved BILSTM algorithm.

With the rapid growth of the agricultural information and the need for data analysis, how to accurately extract useful information from massive data has become an urgent first step in agricultural data mining and application. In this study, an agricultural question-answering information extraction method based on the BE-BILSTM (Improved Bidirectional Long Short-Term Memory) algorithm is designed. Firstly, it uses Python's Scrapy crawler framework to obtain the information of soil types, crop diseases and pests, and agricultural trade information, and remove abnormal values.

Effect of holistic reflective learning program on development of nursing students' professional competency in geriatric clinical practice: a quasi-experimental study.

Background: Reflection is a core competency in geriatric nursing, and reflective learning is an effective approach in nursing education and pracice. An internship program is a transition course that enhances the knowledge, skills, and attitudes of aspiring nursing students in real clinical work. In geriatric clinical setting, nursing internship students require a broad understanding of professional competency that integrates reflective learning with clinical practice to deal with geriatric patient problems and equip them with the knowledge, attitudes, and skills needed to provide quality of care.

Three new species of (Zingiberaceae) from Sabah, Malaysia.

Three new species of , , and were discovered in Sabah, Malaysia. is similar to R.M.

Novel swing lock denture design utilizing magnets for a patient with mandibular resection.

Mandibular defects requiring reconstructions may result from mandibular resections due to benign or malignant lesions. Prosthesis-based rehabilitation of such cases represents a challenge due to various anatomical and functional limitations. Here we present a novel design for the fabrication of a swing lock denture utilizing a simplified hinge and magnets for a patient who had undergone hemimandibulectomy.

Clinical characteristics and outcomes of Fusarium infections in adult patients after hematopoietic stem cell transplantation: A meta-summary of case reports.

Fusarium infections have increased, particularly among patients with hematological malignancies and in those receiving hematopoietic stem cell transplantation (HSCT). This meta-summary summarizes the clinical characteristics, treatment, and outcomes of Fusarium infections in HSCT recipients. The PubMed, ScienceDirect, and Ovid SP databases were searched from inception to January 2024 to identify relevant case reports.

Live Fish in the Throat Causing Upper Airway Obstruction and Esophageal Perforation.

Having a large live fish stuck in the throat is rare and prompts the urgent need to secure a definitive airway. Such sizeable foreign body (FB) in the aerodigestive tract also poses a constant threat of hollow viscus perforation, and the removal process can be complex. This report describes a fishing mishap causing the impaction of a large live fish in the laryngopharynx and esophagus, leading to respiratory distress and upper esophageal perforation.

Investigating the synergistic effects of internal curing and pozzolanic activity in mortar utilizing clay-burnt brick fines.

This study investigates the combined effect of internal curing and pozzolanic activity in mortar through the incorporation of clay-burnt brick fines (CBBF) as a partial substitute for sand. Simultaneously, the study explores the degree of pozzolanic reactivity by replacing a part of cement with finer clay-burnt brick fines (CBBP, particle size <75 μm). These materials are sourced from waste materials generated during brick-chip production.

A Systematic Search and Review of Registered Pharmacological Therapies Investigated to Improve Outcomes after a Stroke.

Introduction: Stroke burden is largely due to long-term impairments requiring prolonged care and loss of productivity. We aim to identify and assess studies of different registered pharmacological therapies as treatments for improving post-stroke impairments and/or disabilities.

Methods: In a systematic search and review (PROSPERO registration: CRD42022376973), studies of treatments that have been investigated as recovery-enhancing or recovery-promoting treatments in adult patients who had suffered a stroke will be searched for, screened, and reviewed based on the following: participants (P): adult humans, aged 18 years or older, diagnosed with stroke; interventions (I): registered or marketed pharmacological therapies that have been investigated as recovery-enhancing or recovery-promoting treatments in stroke; comparators (C): active or placebo or no comparator; outcomes (O): stroke-related neurological impairments and functional/disability assessments.

Incidence and effect of an extra root on the crown morphometry of the maxillary second molars among Malaysian Mongoloids.

Background: This study aimed to investigate whether the presence of two palatal roots on permanent maxillary second molars (MSMs) can affect the crown size and crown's buccolingual and mesiodistal diameters.

Materials And Methods: A retrospective study was conducted using 592 CBCT scans to investigate 1120 MSMs of Mongoloid Malaysians. 3D models were created to assess the four-rooted MSMs and other related teeth carefully.