Coding-Complete Sequence of a SARS-CoV-2 Strain from an Omicron (B.1.1.529+BA.1) Variant Detected in Morocco.

Here, we describe the coding-complete sequence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) strain HM36, identified as a strain of concern of B.1.1.

Chemical Composition, Antioxidant and Antibacterial Activities of Boiss and (L.) Hoffmann and Link Essential Oils.

and are two Moroccan endemic medicinal plants used traditionally by the local population. The present study aims to investigate their essential oil chemical composition, antioxidant and antibacterial activities. The chemical composition of the essential oils was determined using the GC-MS analysis, the antioxidant activity assessed using DPPH and FRAP methods while the antimicrobial activity was evaluated against nine bacteria species tested (, , , , sensitive , sensitive , resistant , resistant and ).

Post-Validation Survey in Two Districts of Morocco after the Elimination of Trachoma as a Public Health Problem.

Trachoma is the leading infectious cause of blindness. In 2016, Morocco was validated by WHO as having eliminated trachoma as a public health problem. We evaluated two previously endemic districts in Morocco for trachomatous inflammation-follicular (TF), trachomatous trichiasis (TT), and antibodies against Chlamydia trachomatis, the causative agent of trachoma.

Secondary-metabolites fingerprinting of Argania spinosa kernels using liquid chromatography-mass spectrometry and chemometrics, for metabolite identification and quantification as well as for geographic classification.

Argan (Argania spinosa L.) fruit kernels' composition has been poorly studied and received less research intensity than the resulting Argan oil. The Moroccan Argan kernels contain a wealth of metabolites and can be investigated for nutritional and health aspects as well as for economic benefits.

Coeliac disease hidden by cryptogenic hypertransaminasaemia in children: a case report.

Celiac disease is a chronic immune-mediated multisystem disorder that may affect several organs. Isolated hypertransaminasemia, with mild or nonspecific histologic changes in the liver biopsy, also known as "celiac hepatitis", is the most frequent presentation of liver injury in celiac disease. Both, histologic changes and liver enzymes reverse to normal after treatment with a gluten-free diet in most patients.

Authentication of extra virgin Argan oil by selected-ion flow-tube mass-spectrometry fingerprinting and chemometrics.

Recognized for its nutritional and therapeutic use, extra-virgin Argan Oil (EVAO) is frequently adulterated. Selected-Ion Flow-Tube Mass Spectrometry (SIFT-MS) spectra were applied to quantify adulterants (i.e.

Analysis of Mutants Affecting Regulation of Methionine, Trehalose, and Inositol Metabolisms Suggests a Role in Stress Adaptation and Symbiosis Development.

Isolated from desert, the nitrogen-fixing bacterium LMR001 is capable of survival under particularly harsh environmental conditions. To obtain insights in molecular mechanisms involved in stress adaptation, a recent study using RNAseq revealed that the RpoE2-mediated general stress response was activated under mild saline stress but appeared non-essential for the bacterium to thrive under stress and develop the symbiosis. Functions associated with the stress response included the metabolisms of trehalose, methionine, and inositol.

Spontaneous uterine rupture revealing vascular Ehlers-Danlos syndrome: An uncommon case report.

Introduction And Importance: Vascular Ehlers-Danlos syndrome also referred to as Ehlers-Danlos Type IV is an uncommon autosomal dominant genetic disorder linked to connective tissue abnormality. Its evolution is marked by the occurrence of severe vascular, digestive and obstetrical complications. The current case highlights the importance of early diagnosis and physician awareness about this disorder as it can improve the patient's prognosis.

Coding-Complete Genome Sequences of a Delta Subvariant (AY.33) of SARS-CoV-2 Obtained from Moroccan COVID-19 Patients.

We report here the complete genome sequences of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) strains obtained from Moroccan patients with COVID-19. The analysis of these sequences indicates that the identified strains belong to the AY.33 sublineage of the Delta variant.

Cytometric analysis and clinical features in a Moroccan cohort with severe combined immunodeficiency.

Severe combined immunodeficiency (SCID) is a form of primary immunodeficiency disease (PID). It is characterized by a serious abnormality of the cellular and sometimes humoral system due to a deficiency in development of T cells, B cells and/or NK cells. The early diagnosis of SCID improves the prognosis.

Experimental validation of a linac head Geant4 model under a grid computing environment.

This work aims to present the strategy to simulate a clinical linear accelerator based on the geometry provided by the manufacturer and summarize the corresponding experimental validation. Simulations were performed with the Geant4 Monte Carlo code under a grid computing environment. The objective of this contribution is reproducing therapeutic dose distributions in a water phantom with an accuracy less than 2%.

Machine learning approaches in Covid-19 severity risk prediction in Morocco.

The purpose of this study is to develop and test machine learning-based models for COVID-19 severity prediction. COVID-19 test samples from 337 COVID-19 positive patients at Cheikh Zaid Hospital were grouped according to the severity of their illness. Ours is the first study to estimate illness severity by combining biological and non-biological data from patients with COVID-19.

Ethnopharmacological Survey and Comparative Study of the Healing Activity of Moroccan Thyme Honey and Its Mixture with Selected Essential Oils on Two Types of Wounds on Albino Rabbits.

Wound healing consists of several continuous phases involving various cells and chemical intermediates. As a rich source of nutrition elements, honey has proved to have potential benefits in the treatment of various diseases. The present study was designed to investigate the healing effect of a honey mixture with selected essential oils on chemical and thermal wound models in rabbits.

Vegetation climate and marine environmental reconstruction in the western Mediterranean (southern Rifian corridor, Morocco) over the Tortonian-Messinian transition.

The Southern Rifian Corridor was a gateway connecting the Mediterranean Sea to the Atlantic Ocean in the Late Miocene. Its rapid narrowing at the Tortonian - Messinian transition around 7.2 Ma, resulting from very intense tectonic activity, has triggered an ecological crisis well before the deposition of the Messinian Salinity crisis evaporites.

Air-pollution prediction in smart city, deep learning approach.

Over the past few decades, due to human activities, industrialization, and urbanization, air pollution has become a life-threatening factor in many countries around the world. Among air pollutants, Particulate Matter with a diameter of less than ( ) is a serious health problem. It causes various illnesses such as respiratory tract and cardiovascular diseases.

Thymoma may explain the confusion: a case report.

Background: The association of inflammatory myopathy and myasthenia gravis is a rarely described entity whose clinical presentation has always been intriguing because of the great clinical similarity between these two pathologies. The presence of a thymic pathology often explains this combination, whose mechanisms are very complex.

Case Presentation: A 56-year-old woman of North African origin, was hospitalized to explore the Raynaud phenomenon associated with proximal muscle weakness, pain, and arthralgia.

Adnexal torsion caused by tuberculous pyosalpinx: An uncommon case report of urogenital tuberculosis.

Background: According to the World Health Organization, TB is a global public health problem and it remains in 2020 the deadliest infectious disease in the world, ahead of Covid19 (Global Tuberculosis Report 2020, 2020). Morocco is an endemic area with more than 30,000 new cases of all forms of tuberculosis each year (Plan stratégique national 2018-2021 de lutte antituberculeuse, 2018). UGTB is the second most frequent localization after lymph node involvement and is responsible for 30 to 40% of all extrapulmonary cases.

Coronectomy of mandibular wisdom teeth: A case series.

Introduction And Importance: Coronectomy represents a common procedure performed in oral surgery, mostly involving the lower wisdom teeth when the extraction presents a risk of injury to the inferior alveolar nerve (NAI). The surgical approach can be described as a coronal separation of the tooth and leaving the roots intact in the socket. The result is impressive with the disappearance of the symptomatology at first and especially the root migration, which occurs most frequently in the first 6 months.

Impact of Ramadan fasting on disease activity in patients with multiple sclerosis: a multicenter study.

Background: The safety of Ramadan fasting for Muslim patients suffering from multiple sclerosis (MS) is still a matter of debate. This work aimed to study the clinical course of MS during Ramadan fasting and to clarify the predictors of relapses and symptoms exacerbation.

Methods: This retrospective study included 153 Muslim patients with MS.

Breast tuberculosis: A forgotten diagnosis.

Breast tuberculosis is a rare entity even in endemic countries. It is often considered as a diagnostic conundrum given the non-specific clinical and imaging characteristics. Therefore, the definitive diagnosis is based on the identification of bacilli by microbiological or histopathological examination.

Survival analysis of all critically ill patients with COVID-19 admitted to the main hospital in Mogadishu, Somalia, 30 March-12 June 2020: which interventions are proving effective in fragile states?

Objectives: To determine risk factors for death in patients with coronavirus disease 2019 (COVID-19) admitted to the main hospital in Somalia, and identify interventions contributing to improved clinical outcome in a low-resource and fragile setting.

Methods: A survival analysis was conducted of all patients with COVID-19 admitted to the main hospital in Somalia from 30 March to 12 June 2020.

Results: Of the 131 patients admitted to the hospital with COVID-19, 52 (40%) died and 79 (60%) survived.

Chemical Composition and In Vitro Antioxidant and Antimicrobial Activities of L.

In this study, the polyphenol content and the antioxidant and antimicrobial activities of hydroethanolic (MVE) and hydroacetonic (MVA) leaf extracts of L. were examined. The results indicated that the total phenolic content was higher in MVA (112.