149 results match your criteria: "University Medical Imaging Toronto[Affiliation]"

The healthcare sector is a major contributor to the universal climate footprint, of this a significant proportion is attributable to medical imaging and further to dedicated cardiac imaging. The increasing availability and utility of cardiac imaging techniques for prognosis, diagnosis and management raises concerns for the impact of these investigations on the environment. Our objective was to review the published literature assessing the environmental impact of non-invasive imaging modalities within cardiology, subsequently helping guide physicians toward a more sustainable approach to cardiac imaging and improved awareness of the environmental impact of healthcare within this field.

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Does ultrasound guidance decrease femoral access site complications in neurointerventional procedures? A retrospective cohort study.

Eur J Radiol

December 2024

The Division of Neuroradiology, Joint Department of Medical Imaging and University Medical Imaging Toronto, Toronto Western Hospital, University Health Network, 399 Bathurst Street, Toronto, Ontario M5T 2S8, Canada; Lahey Hospital & Medical Center, TH Chan School of Medicine, University of Massachusetts, Boston, United States.

Background: Ultrasound has been increasingly used to guide femoral arterial access for neuroendovascular procedures. Its effect on the safety outcomes has yet to be established.

Purpose: The purpose is to determine the effect of ultrasound-guided punctures on femoral access site complications (ASC), and to identify other potential predictors of ASC.

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Retrieval-Augmented Generation for Large Language Models in Radiology: Another Leap Forward in Board Examination Performance.

Radiology

October 2024

From the University Medical Imaging Toronto, Joint Department of Medical Imaging, Toronto General Hospital, Department of Medical Imaging, University of Toronto, 200 Elizabeth St, Peter Munk Bldg, 1st Fl, Toronto, ON, Canada M5G 24C.

Article Synopsis
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Ex vivo lung perfusion (EVLP) enables advanced assessment of human lungs for transplant suitability. We developed a convolutional neural network (CNN)-based approach to analyze the largest cohort of isolated lung radiographs to date. CNNs were trained to process 1300 longitudinal radiographs from n = 650 clinical EVLP cases.

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F-Fluoroazomycin Arabinoside (FAZA) PET/MR as a Biomarker of Hypoxia in Rectal Cancer: A Pilot Study.

Tomography

August 2024

University Medical Imaging Toronto, University Health Network, Sinai Health Systems, Women's College Hospital, University of Toronto, Toronto, ON M5G 2N2, Canada.

Tumor hypoxia is a negative prognostic factor in many tumors and is predictive of metastatic spread and poor responsiveness to both chemotherapy and radiotherapy. To assess the feasibility of using F-Fluoroazomycin arabinoside (FAZA) PET/MR to image tumor hypoxia in patients with locally advanced rectal cancer (LARC) prior to and following neoadjuvant chemoradiotherapy (nCRT). The secondary objective was to compare different reference tissues and thresholds for tumor hypoxia quantification.

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The health of Canadians is already impacted by climate change due to wildfire smoke, heat domes, floods, droughts, and the changing distribution of vector borne disease. The healthcare sector contributes to climate change, accounting for approximately 4.6% of annual greenhouse gas emissions in Canada.

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There has been a rapid expansion in centers performing balloon pulmonary angioplasty (BPA) and pulmonary thromboendarterectomy (PTE) for chronic thromboembolic pulmonary hypertension (CTEPH). The purpose of this scoping review was to identify cardiothoracic imaging predictors of outcomes and to identify gaps to address in future work. A scoping review was conducted using the framework outlined by Arksey and O'Malley and Levac et al.

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Our purpose was to prospectively assess the distribution of NETPET scores in well-differentiated (WD) grade 2 and 3 gastroenteropancreatic (GEP) neuroendocrine tumors (NETs) and to determine the impact of the NETPET score on clinical management. This single-arm, institutional ethics review board-approved prospective study included 40 patients with histologically proven WD GEP NETs. Ga-DOTATATE PET and F-FDG PET were performed within 21 d of each other.

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CXCR4-Targeted PET Imaging in Hematologic Malignancies: A Systematic Review and Meta-analysis.

Clin Nucl Med

January 2025

From the Joint Department of Medical Imaging, University Medical Imaging Toronto, University Health Network, Mount Sinai Hospital & Women's College Hospital, University of Toronto, Toronto, Ontario, Canada.

Purpose: The aims of this study were to perform a comprehensive review and meta-analyses and to report pooled diagnostic results on CXCR4-targeted PET, particularly considering detection, visualization, and prognostication.

Patients And Methods: This study followed PRISMA-DTA. A systematic search was conducted on major medical literature databases up to March 1, 2024.

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Vascular Ehlers-Danlos syndrome (vEDS) is a rare and aggressive heritable aortic disease caused by pathogenic variants in COL3A1 gene, characterized by spontaneous arterial dissection and organ rupture. The purpose of this study is to evaluate ventricular size and function and to explore their associations with complications in vEDS. Adults with genetically confirmed vEDS who underwent clinical cardiac MRI were retrospectively compared with controls matched for age and sex.

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Article Synopsis
  • - Peripartum cardiomyopathy (PPCM) is a heart condition that occurs in women during late pregnancy and shortly after childbirth, and cardiovascular magnetic resonance (CMR) is important for diagnosing and managing it.
  • - A study involving 32 women with PPCM found they had significantly lower left ventricular (LV) ejection fractions and higher LV end-diastolic volumes compared to 26 healthy controls, and 58% of PPCM patients exhibited specific late gadolinium enhancement (LGE) patterns.
  • - Most PPCM patients showed improvement in heart function, with 92% demonstrating an increased LV ejection fraction at follow-up, highlighting the potential for CMR findings to guide diagnosis and management in clinical practice
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Background: BAL cellular analysis is often recommended during the initial diagnostic evaluation of fibrotic interstitial lung disease (ILD). Despite recommendation for its use, between-center heterogeneity exists and supportive data concerning the clinical utility and correlation of BAL findings with radiologic features or patterns remain sparse.

Research Question: In patients with fibrotic ILD, are BAL findings associated with radiologic features, patterns, and clinical diagnoses?

Study Design And Methods: Patients with fibrotic ILD who underwent BAL for diagnostic evaluation and who were enrolled in the prospective Canadian Registry for Pulmonary Fibrosis were re-reviewed in a standardized multidisciplinary discussion (MDD).

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  • The IELSG37 trial investigated whether patients with primary mediastinal B-cell lymphoma (PMBCL) who have a complete metabolic response (CMR) after treatment can safely skip consolidation radiotherapy.
  • It was a randomized noninferiority study involving 545 patients, focusing on progression-free survival (PFS) over 30 months, with results showing high PFS rates of 96.2% for observation and 98.5% for radiotherapy.
  • The study concluded that avoiding irradiation does not negatively impact survival, highlighting positive outcomes for patients with CMR.
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Article Synopsis
  • - Cardiovascular imaging is becoming increasingly important for diagnosing and managing cardiovascular disease, highlighting the need for standardized practices.
  • - The European Society of Cardiovascular Radiology (ESCR) aims to enhance the credibility and quality of their scientific documents through a rigorous consensus development methodology.
  • - By establishing clear guidelines for producing ESCR documents, the society seeks to improve the overall impact on patient management and health outcomes in cardiovascular care.
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Value of Dynamic Contrast-Enhanced MRI for Grade Group Prediction in Prostate Cancer: A Radiomics Pilot Study.

Acad Radiol

January 2025

University Medical Imaging Toronto, Toronto Joint Department Medical Imaging, University Health Network, Sinai Health System, Women's College Hospital, University of Toronto, Toronto, Ontario, Canada.

Rationale And Objectives: To determine the role of dynamic contrast-enhanced (DCE) MRI-radiomics in predicting the International Society of Urological Pathology Grade Group (ISUP-GG) in therapy-naïve prostate cancer (PCa) patients.

Materials And Methods: In this ethics review board-approved retrospective study on two prospective clinical trials between 2017 and 2020, 73 men with suspected/confirmed PCa were included. All participants underwent multiparametric MRI.

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Immediate and strategic action is needed to improve environmental sustainability and reduce the detrimental effects of climate change. Climate change is already adversely affecting the health of Canadians related to worsening air pollution and wildfire smoke, increasing frequency and intensity of extreme weather events, and expansion of vector-borne and infectious illnesses. On one hand, radiology contributes to the climate crisis by generating greenhouse gas emissions and waste during the production, manufacture, transportation, and use of medical imaging equipment and supplies.

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Sigmoid volvulus-Can CT features predict outcomes and recurrence?

Eur Radiol

July 2024

Department of Medical Imaging, University Medical Imaging Toronto, University of Toronto, Toronto, Canada.

Objectives: Sigmoid volvulus (SV) is a common cause of bowel obstruction, especially in older patients. SV can be mesenteroaxial (M-SV) or organoaxial (O-SV). The purpose of this study was to assess if CT findings in SV are associated with clinical outcomes.

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Predictive [F]-FDG PET/CT-Based Radiogenomics Modelling of Driver Gene Mutations in Non-small Cell Lung Cancer.

Acad Radiol

December 2024

University Medical Imaging Toronto, Toronto Joint Department Medical Imaging, University Health Network, Sinai Health System, Women's College Hospital, University of Toronto, M5G 2N2, Toronto, Ontario, Canada (R.H., R.K., A.K., V.M., S.A.M., C.O., U.M., M.M., P.V.H.).

Rationale And Objectives: To investigate whether [F]-FDG PET/CT-derived radiomics may correlate with driver gene mutations in non-small cell lung cancer (NSCLC) patients.

Materials And Methods: In this IRB-approved retrospective study, 203 patients with surgically treated NSCLC who underwent subsequent genomic analysis of the primary tumour at our institution between December 2004 and January 2014 were identified. Of those, 128 patients (mean age 62.

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Active surveillance (AS) is a conservative management option recommended for patients diagnosed with low-risk prostate cancer (PCa) and selected cases with intermediate-risk PCa. The adoption of prostate MRI in the primary diagnostic setting has sparked interest in its application during AS. This review aims to examine the role and performance of multiparametric MRI (mpMRI) across the entire AS pathway, from initial stratification to follow-up, also relative to the utilization of the Prostate Cancer Radiological Estimation of Change in Sequential Evaluation (PRECISE) criteria.

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Canadian radiology: 2024 update.

Diagn Interv Imaging

November 2024

Department of Medical Imaging, Temerty Faculty of Medicine, University of Toronto, Toronto, ON M5S1A8, Canada; University Medical Imaging Toronto, Joint Department of Medical Imaging, University Health Network (UHN), Toronto, ON M5G1X6, Canada.

Radiology in Canada is advancing through innovations in clinical practices and research methodologies. Recent developments focus on refining evidence-based practice guidelines, exploring innovative imaging techniques and enhancing diagnostic processes through artificial intelligence. Within the global radiology community, Canadian institutions play an important role by engaging in international collaborations, such as with the American College of Radiology to refine implementation of the Ovarian-Adnexal Reporting and Data System for ultrasound and magnetic resonance imaging.

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Background: Cardiac MRI feature tracking (FT) allows objective assessment of segmental left ventricular (LV) function following a myocardial infarction (MI), but its utilization in sheep, where interventions can be tested, is lacking.

Purpose: To apply and validate FT in a sheep model of MI and describe post-MI LV remodeling.

Study Type: Animal model, longitudinal.

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Noninvasive Pressure-Volume Loops: Can Cardiac MRI Obviate the Need for Invasive Catheter Hemodynamic Measurements?

JACC Adv

June 2024

Department of Cardiovascular Sciences, University of Leicester and the NIHR Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, United Kingdom.

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