Regional ventilation distribution before and after laparoscopic lung parenchymal resection.

The aim of the present study was to evaluate the influence of one-sided pulmonary nodule and tumour on ventilation distribution pre- and post- partial lung resection.A total of 40 consecutive patients scheduled for laparoscopic lung parenchymal resection were included. Ventilation distribution was measured with electrical impedance tomography (EIT) in supine and surgery lateral positions 72 h before surgery (T1) and 48 h after extubation (T2).

Electrical Impedance Tomography to Monitor Hypoxemic Respiratory Failure.

Hypoxemic respiratory failure is one of the leading causes of mortality in intensive care. Frequent assessment of individual physiological characteristics and delivery of personalized mechanical ventilation (MV) settings is a constant challenge for clinicians caring for these patients. Electrical impedance tomography (EIT) is a radiation-free bedside monitoring device that is able to assess regional lung ventilation and changes in aeration.

The influence of gravity on electrical impedance tomography measurements during upper body position change.

Objective: The aim of the study was to examine the influence of gravity on regional ventilation measured by electrical impedance tomography (EIT) with the standard electrode belt position at the 5th intercostal space during tilting from supine to sitting positions.

Methods: A total of 30 healthy volunteers were examined prospectively in supine position during quiet tidal breathing. Subsequently, the bed was tilted so that the upper body of the subjects achieved 30, 60 and 90° every 3 min.

The calculation of electrical impedance tomography based silent spaces requires individual thorax and lung contours.

The present study evaluates the influence of different thorax contours (generic versus individual) on the parameter 'silent spaces' computed from electrical impedance tomography (EIT) measurements.Six patients with acute respiratory distress syndrome were analyzed retrospectively. EIT measurements were performed and the silent spaces were calculated based on (1) patient-specific contours S, (2) generic adult male contours Sand (3) generic neonate contours S.

Regional ventilation distribution in patients with scoliosis assessed by electrical impedance tomography: Is individual thorax shape required?

Background: Electrical impedance tomography (EIT) is a non-invasive non-radiological regional lung function measurement. The aim of the study was to examine the feasibility of assessing ventilation distribution with EIT in scoliosis patients using generic and individual thorax shape.

Methods: Eight subjects were measured with EIT before scoliosis surgery.

Similar severity of influenza primary and re-infections in pre-school children requiring outpatient treatment due to febrile acute respiratory illness: prospective, multicentre surveillance study (2013-2015).

Background: Influenza virus infections in immunologically naïve children (primary infection) may be more severe than in children with re-infections who are already immunologically primed. We compared frequency and severity of influenza virus primary and re-infections in pre-school children requiring outpatient treatment.

Methods: Influenza-unvaccinated children 1-5 years of age presenting at pediatric practices with febrile acute respiratory infection < 48 h after symptom onset were enrolled in a prospective, cross-sectional, multicenter surveillance study (2013-2015).

Regional ventilation distribution in healthy lungs: can reference values be established for electrical impedance tomography parameters?

Background: Although electrical impedance tomography (EIT) is widely used for monitoring regional ventilation distribution, reference values have yet to be established for clinical use. The present study aimed to evaluate the feasibility of creating reference values for standard EIT parameters for potential clinical application.

Methods: A total of 75 participants with healthy lungs were included in this prospective study (male:female, 48:27; age, 34±14 years; height, 172±7 cm; weight, 73±12 kg).

Lung regions identified with CT improve the value of global inhomogeneity index measured with electrical impedance tomography.

Background: The global inhomogeneity () index is a functional electrical impedance tomography (EIT) parameter which is used clinically to assess ventilation distribution. However, may underestimate the actual heterogeneity when the size of lung regions is underestimated. We propose a novel method to use anatomical information to correct the index calculation.

Lung ventilation distribution in patients after traditional full sternotomy and minimally invasive thoracotomy: An observational study.

Background: The aim of the study was to examine the post-operative ventilation distribution changes in cardiac surgical patients after traditional full sternotomy (FS) or minimally invasive thoracotomy (MIT).

Methods: A total of 40 patients scheduled for FS with two-lung ventilation or MIT with one-lung ventilation were included. Ventilation distribution was measured with electrical impedance tomography (EIT) at T1, before surgery; T2, after surgery in ICU before weaning; T3, 24 hours after extubation.

Neonatal Outcome After Preeclampsia and HELLP Syndrome: A Population-Based Cohort Study in Germany.

To analyze short term outcomes of very low birth weight infants (VLBWI) born preterm after maternal preeclampsia and HELLP syndrome within the German Neonatal Network. The German Neonatal Network is a large population-based cohort study enrolling VLBWI since 2009. Two thousand six hundred and fifty two infants below 32 weeks of gestation born after maternal preeclampsia or HELLP syndrome and 13,383 infants born prematurely for other causes between 2009 and 2018 were included in our analysis.

Oxygen Therapy Delivery and Body Position Effects Measured With Electrical Impedance Tomography.

Background: The aim of this prospective randomized crossover study was to compare the short-term effects of high-flow nasal cannula (HFNC) therapy and a 45° head-up tilt to the short-term effects of conventional oxygen (O) therapy in post-abdominal surgery patients.

Methods: A total of 18 subjects who were successfully weaned from ventilator support after abdominal surgery were included in the study. The subjects were randomly assigned to 2 groups: conventional O was applied in group A for 15 min, and HFNC (60 L/min) was applied in group B for 15 min.

The incidence and interpretation of large differences in EIT-based measures for PEEP titration in ARDS patients.

Positive end-expiratory pressure (PEEP) can be titrated by electrical impedance tomography (EIT). The aim of the present study was to examine the performance of different EIT measures during PEEP trials with the aim of identifying "optimum" PEEP and to provide possible interpretations of largely diverging results. After recruitment (maximum plateau pressure 35 cmHO), decremental PEEP trial with steps of 2 cmHO and duration of 2 min per step was performed.

Positive end-expiratory pressure titration with electrical impedance tomography and pressure-volume curve in severe acute respiratory distress syndrome.

Background: The study objective was to compare titration of positive end-expiratory pressure (PEEP) with electrical impedance tomography (EIT) and with ventilator-embedded pressure-volume loop in severe acute respiratory distress syndrome (ARDS).

Methods: We have designed a prospective study with historical control group. Twenty-four severe ARDS patients (arterial oxygen partial pressure to fractional inspired oxygen ratio, PaO/FiO < 100 mmHg) were included in the EIT group and examined prospectively.

Ex vivo hydrodynamics after central and paracommissural edge-to-edge technique: A further step toward transcatheter tricuspid repair?

Objectives: Transcatheter approaches in heart valve disease became tremendously important and are currently established in the aortic position, but transcatheter tricuspid repair is still in its beginning and remains challenging. Replicating the surgical edge-to-edge technique, for example, with the MitraClip System (Abbott Vascular, Santa Clara, Calif), represents a promising option and has been reported successfully in small numbers of cases. However, up to now, few data considering the edge-to-edge technique as a transcatheter approach are available.