425 results match your criteria: "University Medical Center Groningen and University of Groningen.[Affiliation]"

Patient experience in nerve-to-masseter-driven smile reanimation.

J Plast Reconstr Aesthet Surg

August 2019

Department of Otolaryngology/Head and Neck surgery, Facial Nerve Center, Massachusetts Eye and Ear Infirmary and Harvard Medical School, 243 Charles St., Boston, MA 02114, USA.

Introduction: The nerve-to-masseter is one of the most frequently used neural sources in smile reanimation surgery. Very little information has been reported on patient experience with regard to reanimated smile usage and sequelae following transfer. The aim of this study was to quantify patient perception of nerve-to-masseter use in smile reanimation surgery.

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C14:0, C15:0, C17:0 and trans-C16:1(-7) are often used as biomarkers for dairy fat intake. Trans-C18:1(-7) and CLA, two fatty acids which are also present in dairy, have hardly been explored. We investigated whether trans-C18:1(-7) and CLA can enrich the existing biomarker portfolio.

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Rationale: Early pulmonary vascular disease (PVD) after preterm birth is associated with a high risk for developing bronchopulmonary dysplasia (BPD), but its relationship with late respiratory outcomes during early childhood remains uncertain.

Objectives: To determine whether PVD at 7 days after preterm birth is associated with late respiratory disease (LRD) during early childhood.

Methods: This was a prospective study of preterm infants born before 34 weeks postmenstrual age (PMA).

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Article Synopsis
  • Tissue advanced glycation end products (AGEs) indicate metabolic stress and inflammation, linked to cardiovascular issues in hemodialysis patients, with skin autofluorescence (SAF) serving as a key mortality predictor.* -
  • A study measured SAF in 34 hemodialysis patients across different seasons, finding a 5.6% increase in SAF during winter and a significant 10.6% decrease in summer, which coincided with a rise in HbA1c levels for diabetic patients.* -
  • The results suggest that SAF levels decrease in the summer, highlighting the need for further research to identify factors that could reduce SAF and related cardiovascular risks in hemodialysis patients.*
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Objectives: To investigate the correlation between facial palsy severity and quality of life in a broad cohort of facial palsy patients and to elucidate factors that influence this relationship.

Study Design: Retrospective study.

Methods: Records of patients presenting with a clinician-graded facial function (eFACE) and facial palsy-specific quality-of-life patient-reported outcome measure (FaCE) scale from the same moment were reviewed.

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A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper.

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Compensatory gomerular filtration rate (GFR) increase after kidney donation results in a GFR above 50% of the predonation value. The renal functional reserve (RFR) assessed by the renal response to dopamine infusion (RFR) is considered to reflect functional reserve capacity and is thought to be a tool for living donor screening. However, it is unknown if the RFR predicts long-term kidney function.

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Background: Extra-pulmonary neuroendocrine carcinomas (EP-NEC) are rare tumours that require expertise for correct and timely diagnosis, which is essential for clinical decision making. The number of patients affected, treatment given, and the proportion surviving the disease is based on limited evidence. The aim of this study is to retrospectively analyse the incidence, treatment, and relative survival (RS) of EP-NEC patients in the Netherlands.

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Article Synopsis
  • Iron appears to have a harmful impact on chronic kidney disease (CKD) progression, with 33% of CKD biopsies showing iron buildup in kidney tubules, especially in cases with glomerular dysfunction.
  • In healthy kidneys, there are proteins that help manage iron recycling, but in CKD patients, there's an increase in iron importers and storage proteins, while iron export protein levels decrease.
  • The buildup of iron is linked to oxidative stress in the kidneys, suggesting that improper iron management may contribute to kidney damage in CKD.
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Background: Effect of fixed prosthodontics on patients with several agenetic teeth is not well understood.

Purpose: To assess the effect of implant-based fixed prosthodontics on oral health-related quality of life (OHRQoL), general health status, and satisfaction regarding dental appearance, ability to chew and speech in patients with several agenetic teeth.

Materials And Methods: For this prospective cohort study, all patients (≥18 years) with several agenetic teeth who were scheduled for treatment with fixed dental implants between September 2013 and July 2015 at our department were approached.

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Statement Of Problem: Long-term assessments of implant survival and treatment outcome in patients with oligodontia are lacking.

Purpose: The purpose of this retrospective clinical study was to assess which factors determine a long-term implant survival and treatment outcome of up to 25 years in a cohort of patients with oligodontia.

Material And Methods: The medical records of all patients with oligodontia treated with fixed implant prosthodontics between January 1991 and December 2015 in the Department of Oral and Maxillofacial Surgery at the University Medical Center Groningen, the Netherlands, were assessed.

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Objective: The objective of this study was to investigate the long-term effect and treatment stability of selective neurectomy for refractory periocular synkinesis.

Methods: We performed a retrospective review of all patients treated with highly selective neurectomy for refractory periocular synkinesis between August 2009 and August 2015. Primary outcome was time to recommencing treatment for periocular synkinesis.

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Background: Living kidney donor safety requires reliable long-term follow-up of renal function after donation. The current study aimed to define the precision and accuracy of post-donation estimated glomerular filtration rate (eGFR) slopes compared with measured GFR (mGFR) slopes.

Methods: In 349 donors (age 51 ± 10, 54% female), we analysed eGFR according to the 2009 Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation, Modification of Diet in Renal Disease (MDRD) and Cockcroft-Gault/body surface area (CG/BSA), creatinine clearance (CrCl) and mGFR (125I-iothalamate) changes from 3 months until 5 years post-donation.

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Probiotics such as L. plantarum WCFS1 can modulate immune responses in healthy subjects but how this occurs is still largely unknown. Immune-sampling in the Peyer Patches has been suggested to be one of the mechanisms.

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Objectives: To assess long-term (≥10 years) implant survival, peri-implant health, patients' satisfaction and oral health related quality of life (OHQoL) in oligodontia patients rehabilitated with implant-based fixed prosthodontics.

Methods: All oligodontia patients treated ≥10 years previously with implant-based fixed prosthodontics at the University Medical Center Groningen, The Netherlands, were approached to participate. Clinical (plaque index, bleeding index, pocket probing depth) and radiographic (marginal bone level) data were collected between February and May 2016.

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Objective: The optimal frequency of self-monitoring of blood glucose (SMBG) in patients with type 2 diabetes (T2DM) with stable glycemic control is unknown. This study investigated effects of 3 frequencies of SMBG on glycemic control and quality of life after 9 months in patients using one long-acting insulin injection a day. In an open-label, multi-center, primary-care, parallel (1:1:1) randomized trial in the Netherlands including patients with T2DM, HbA1c ≤ 58 mmol/mol (≤ 7.

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Abnormal beta power is a hallmark of explicit movement control in functional movement disorders.

Neurology

January 2018

From St. George's (T.T., G.N., M.J.E.), University of London, and St. George's University Hospitals NHS Foundation Trust, London, UK; Instituto de Medicina Molecular (T.T.), Faculdade de Medicina, Universidade de Lisboa & Serviço de Neurologia, Hospital de Santa Maria, Portugal; Department of Neurology (A.M.M.), University Medical Center Groningen and University of Groningen, the Netherlands; Sobell Department of Motor Neuroscience and Movement Disorders (S.L., A.M.), University College of London, Institute of Neurology; Faculty of Health, Social Care and Education (R.G.), Kingston University and St. George's, University of London, UK; and Neurology Department (I.P.), Hospital Ruber Internacional, Madrid, Spain.

Objective: To determine whether sensorimotor beta-frequency oscillatory power is raised during motor preparation in patients with functional movement disorders (FMD) and could therefore be a marker of abnormal "body-focused" attention.

Methods: We analyzed motor performance and beta-frequency cortical oscillations during a precued choice reaction time (RT) task with varying cue validity (50% or 95% congruence between preparation and go cues). We compared 21 patients with FMD with 13 healthy controls (HCs).

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Background: Low-normal thyroid function within the euthyroid range has been suggested to enhance atherosclerosis susceptibility. Paraoxonase-1 (PON-1) may protect against atherosclerotic cardiovascular disease development by attenuating oxidative stress. We evaluated relationships of PON-1 with thyroid stimulating hormone (TSH), free T , free T , lipids and apolipoprotein (apo)A-I in euthyroid subjects, and assessed whether such relationships are modified in the context of the metabolic syndrome (MetS).

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Breast-fed infants are susceptible to vitamin D deficiency rickets. The current vitamin D 'adequate intake' (AI) for 0-6-month-old infants is 10 µg/d, corresponding with a human milk antirachitic activity (ARA) of 513 IU/l. We were particularly interested to see whether milk ARA of mothers with lifetime abundant sunlight exposure reaches the AI.

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Motor Cortex Stimulation in Patients Suffering from Chronic Neuropathic Pain: Summary of Expert Meeting and Premeeting Questionnaire, Combined with Literature Review.

World Neurosurg

December 2017

Department of Neurosurgery and Radiology, Universitair Ziekenhuis Brussel, Brussels, Belgium; Center for Neurosciences (C4N), Vrije Universiteit Brussel, Brussels, Belgium.

Background: Motor cortex stimulation (MCS) was introduced in the early 1990s by Tsubokawa and his group for patients diagnosed with drug-resistant, central neuropathic pain. Inconsistencies concerning the details of this therapy and its outcomes and poor methodology of most clinical essays divide the neuromodulation society worldwide into "believers" and "nonbelievers." A European expert meeting was organized in Brussels, Belgium by the Benelux Neuromodulation Society in order to develop uniform MCS protocols in the preoperative, intraoperative, and postoperative courses.

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The effect of dual-sided breast surgery on breast asymmetry: A retrospective clinical evaluation study.

J Plast Reconstr Aesthet Surg

September 2017

Department of Plastic Surgery, University Medical Center Groningen and University of Groningen, Groningen, The Netherlands; Bergman Clinics, Location Heerenveen and Zwolle, The Netherlands. Electronic address:

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Background And Objectives: Hypophosphatemia is common in the first year after kidney transplantation, but its clinical implications are unclear. We investigated the relationship between the severity of post-transplant hypophosphatemia and mortality or death-censored graft failure in a large cohort of renal transplant recipients with long-term follow-up.

Design, Setting, Participants, & Measurements: We performed a longitudinal cohort study in 957 renal transplant recipients who were transplanted between 1993 and 2008 at a single center.

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Background: Job satisfaction is essential for physicians' well-being and patient care. The work ethic of long days and hard work that has been advocated for decades is acknowledged as a threat for physicians' job satisfaction, well-being, and patient safety. Our aim was to determine the actual and preferred job size of physicians and to investigate how these and the differences between them influence physicians' job satisfaction.

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