2 results match your criteria: "University Massachusetts Chan Medical School[Affiliation]"
mRNA initiation and termination are spatially coordinated.
bioRxiv
January 2024
RNA Therapeutics Institute, University of Massachusetts Chan Medical School, Worcester, MA.
The expression of a precise mRNA transcriptome is crucial for establishing cell identity and function, with dozens of alternative isoforms produced for a single gene sequence. The regulation of mRNA isoform usage occurs by the coordination of co-transcriptional mRNA processing mechanisms across a gene. Decisions involved in mRNA initiation and termination underlie the largest extent of mRNA isoform diversity, but little is known about any relationships between decisions at both ends of mRNA molecules.
View Article and Find Full Text PDFCancer Prehabilitation in Practice: the Current Evidence.
Curr Oncol Rep
November 2022
Department of Orthopedics and Physical Rehabilitation, University Massachusetts Chan Medical School, Worcester, MA, USA.
Purpose Of Review: This article serves to describe recent controversies in cancer prehabilitation including efficacy, dose, cost effectiveness, stakeholder input, and international implementation.
Recent Findings: Appropriate frequency, type, and timing have yet to be determined, but high intensity exercise is recommended. Costs are favorable when modeled and information on costs of real-world application are forthcoming.