211 results match your criteria: "University Malaysia Sarawak[Affiliation]"

Introduction: Aplastic anaemia (AA) is a rare disorder of bone marrow failure, characterized by bone marrow hypocellularity with pancytopenia. The annual incidence rates of AA in Asia are observed to be two to three times higher than Europe and North America. Since the introduction of immunosuppressive therapy (IST) and of allogenic stem cell transplant (SCT), the outcome of severe AA has significantly improved.

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Sinonasal carcinoma, a rare and challenging malignancy, originating in the nasal cavity and paranasal sinuses, poses diagnostic and management complexities. This 8-year retrospective analysis at Sarawak General Hospital aims to elucidate demographic trends, histopathological entities, and management outcomes, shedding light on this multifaceted malignancy. Emphasizing the significance of accurate histopathological classification, the study explores the impact on prognostication and treatment strategies.

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Background: Degradation of magnetic resonance imaging (MRI) remains a challenging issue, with noise being a key damaging component introduced due to a variety of environmental and mechanical factors.

Objective: The aim of this research work is to addresses the issue of noise reduction and to predict Alzheimer's disease detection efficiently.

Methods: First, we present a genetic programming (GP) technique for reducing Rician noise in MRI images to pre-process the dataset.

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Cellular senescence, the irreversible arrest of cell division, is a hallmark of aging and a key contributor to age-related disorders. Targeting senescent cells represents a promising therapeutic approach to combat these ailments. This review explores the potential of Garcinia species, a genus rich in flavonoids with established antioxidant and anti-inflammatory properties, as a source of natural anti-senescence agents.

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Article Synopsis
  • Oxygen bubbles from seagrass during photosynthesis may create low-amplitude sounds, which we studied in seagrass beds in Taiwan.
  • These sounds occur in the morning, peak around midday, and fade by midafternoon, reaching frequencies between 1-4 kHz.
  • Factors like sunlight exposure and mechanical pressure can influence the pulse rate of these sounds, leading to the suggestion that they are caused by internal oxygen transport mechanisms in the plant rather than cavitation.
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The growing threat of environmental pollution to global environmental health necessitates a focus on the search for sustainable wastewater remediation materials coupled with innovative remediation strategies. Nano and micro zero-valent iron materials have attracted substantial researchers' attention due to their distinct physiochemical properties. This review article delves into novel micro- and nano-zero valent iron (ZVI) materials, analysing their synthesis methods, and exploring their multifaceted potential as a powerful tool for environmental remediation.

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Flying Doctor Services in Sarawak: A Medical Frontline Experience.

Air Med J

September 2024

Primary Health, Sarawak State Health Department, Sarawak, Malaysia.

Malaysia has a 34.3 million population, with 40% residing in rural areas. Since gaining independence, the Malaysian government put a tremendous focus as well as resources in improving the health care services with the aim of improving the health status of Malaysians.

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Introduction: Medical aesthetic practice is growing rapidly in Malaysia due to rising market demand, yet public understanding of these practices remains limited. This study evaluated the awareness and attitudes towards medical aesthetics among Malaysians.

Methods: A cross-sectional survey was conducted among individuals aged > 18 years old in Malaysia from December 2021 to May 2022.

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Understanding the prevalence of abnormal lung function and its associated factors among patients recovering from COVID-19 is crucial for enhancing post-COVID care strategies. This study primarily aimed to determine the prevalence and types of spirometry abnormalities among post-COVID-19 patients in Malaysia, with a secondary objective of identifying its associated factors. Conducted at the COVID-19 Research Clinic, Faculty of Medicine, University Technology MARA, from March 2021 to December 2022, this study included patients at least three months post-discharge from hospitals following moderate-to-critical COVID-19.

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In aquatic environments, Vibrio and cyanobacteria establish varying relationships influenced by environmental factors. To investigate their association, this study spanned 5 months at a local shrimp farm, covering the shrimp larvae stocking cycle until harvesting. A total of 32 samples were collected from pond A (n = 6), pond B (n = 6), effluent (n = 10), and influent (n = 10).

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The Waorani, an isolated indigenous tribe in Ecuador, have long been characterized by limited genetic diversity, with few studies delving into their genetic background. Human Leukocyte Antigen (HLA) genes which are located in the human major histocompatibility complex (MHC) provides valuable insights into population evolution due to its highly polymorphic nature. However, little is known about the HLA diversity and ancestry of the Waorani population.

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Effectiveness of a pharmacist-led, community group-based education programme in enhancing diabetes management: A multicentre randomised control trial.

Contemp Clin Trials Commun

April 2024

Pharmacy Practice and Development, Pharmacy Service Division, Sarawak State Health Department, Malaysia.

Aims: This study presents a protocol for the Pharmacy Integrated Community Care (PICC) program, meticulously designed to enhance Hemoglobin A1c (HbA1c) levels and augment knowledge about diabetes mellitus (DM) among individuals diagnosed with Type 2 Diabetes Mellitus (T2DM) in the Sarawak State of Malaysia.

Methods: From 1 May to December 31, 2023, a prospective, multicenter, parallel-design randomised controlled trial will be conducted with two groups, each consisting of 47 participants. The intervention group will receive a structured, four-session group-based program guided by experienced pharmacists, focusing on medication adherence and diabetes management.

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In Malaysia, despite achieving leprosy-elimination status in 1994, leprosy remains a public health issue among the indigenous Penan community in Sarawak. This study aimed to determine the prevalence trend and clinical profile of leprosy among the Penans in rural Baram, Sarawak, Malaysia. A retrospective records review was conducted on 10-year (2008-2018) time trend of annual prevalence rate and 5-year (2013-2018) Penan leprosy patient clinical profile.

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Introduction: Malaysia entered the transition to the endemic phase of Coronavirus 2019 (COVID-19) on 1st April 2022. This study aims to determine the public's willingness to perform COVID-19 self-testing. Factors that influenced their willingness were also assessed.

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A Review of the Ethnomedicinal, Phytochemical, and Anticancer Properties of Melicope Species.

Chem Biodivers

December 2023

Department of Chemistry, Faculty of Resource Science and Technology, University Malaysia Sarawak, 94300, Kota Samarahan Sarawak, Malaysia.

The genus Melicope, which consists of 230 species, stands out as the largest genus within the Rutaceae family. Melicope species are characterized by their evergreen nature and can range from shrubs to predominantly dioecious trees. The Melicope species have been utilized in traditional medicine to address a wide range of ailments, including fever, colds, cramps, and inflammation.

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Dual practice within public hospitals, characterised by the concurrent provision of public and private healthcare services within public hospitals, has become a widespread phenomenon. With the participation of selected public hospitals, dual practice within public hospitals, also known as Full Paying Patient services, was an initiative the Ministry of Health Malaysia took in 2007 to retain senior specialist physicians in Malaysia. The revenue generated from the Full Paying Patient services aims to provide an avenue for public sector specialists to supplement their incomes while alleviating the Government's burden of subsidising healthcare for financially capable individuals.

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A case of intussusception secondary to a metastatic malignant melanoma from the nasal cavity.

J Surg Case Rep

October 2023

General Surgery, Sarawak General Hospital, Jalan Hospital, 93586 Kuching, Sarawak, Malaysia.

About 5% of all intussusception are found in adults, up to 90% of these have an anatomical lesion with ~50% of them are malignant. Malignant melanoma commonly metastasizes to the small bowel; however, melanoma causing intussusception is rare. We describe a 57-year-old lady with a history of surgically treated malignant melanoma in her nasal cavity who came with an ambiguous intestinal obstruction.

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This study aimed to investigate the physiochemical properties of Sarawak's adapted Liberica coffee silverskin (CS) using multiple solvents (distilled water, methanol, and ethanol) and its impact on the total phenolic content (TPC), total flavonoid content (TFC), and antioxidant activities of the CS. The results showed that the highest TPC was observed in the methanol extract (15.24 ± 0.

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, commonly known as coffee, is a kind of coffee that originated in Liberia, a West African country. It is considered a less-known coffee bean variety, which accounts for less than 2% of commercially produced coffee worldwide. In this study, the influences of optimization of microwave-assisted extraction (MAE) on the total phenolic content (TPC), total flavonoid content (TFC), and total carbohydrate content (TCC) of bioactive compounds extracted from Sarawak sp.

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A Rare Case of Complicated Sinonasal Meliodosis Mimicking Sinonasal Lymphoproliferative Disease.

Indian J Otolaryngol Head Neck Surg

September 2023

Otorhinolaryngology Head and Neck Department, Sarawak General Hospital, Kuching, Sarawak Malaysia.

Unilateral nasal obstruction with purulent nasal discharge is one of the presentations for sinonasal melioidosis. However, it may mimic nasal NK/T cell lymphoma. Both causing tissue destruction involving nasal septum, lateral nasal wall and palate.

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Multimodal medical image fusion in NSST domain with structural and spectral features enhancement.

Heliyon

June 2023

Multimedia Information Processing Lab, Department of Information and Communication Engineering, Chosun University, Gwangju, South Korea.

For the past 25 years, medical imaging has been extensively used for clinical diagnosis. The main difficulties in medicine are accurate disease recognition and improved therapy. Using a single imaging modality to diagnose disease is challenging for clinical personnel.

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ARIA Care Pathways 2019: Next-Generation Allergic Rhinitis Care and Allergen Immunotherapy in Malaysia.

J Pers Med

May 2023

Institute of Allergology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, 13353 Berlin, Germany.

An increase in the prevalence of allergic rhinitis (AR) worldwide presents a significant burden to the health care system. An initiative was started in Europe designated as Allergic Rhinitis and Its Impact on Asthma (ARIA) to develop internationally applicable guidelines by utilising an evidence-based approach to address this crucial issue. The efforts are directed at empowerment of patients for self-management, the use of digital mobile technology to complement and personalise treatment, and establishment of real-life integrated care pathways (ICPs).

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Unlabelled: Recurrent epistaxis represents an alarming sign that may suggest a sinister aetiology, especially in patients with previous head and neck malignancy. The recognition of certain potentially life-threatening conditions, namely pseudoaneurysm or tumour recurrence, remains prudence to avoid disastrous repercussion. Nasal endoscopy has become an essential tool in otolaryngology.

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