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Clinical evaluation of a loop-mediated amplification kit for diagnosis of imported malaria.

J Infect Dis

August 2013

Department of Clinical Parasitology, Walk-in Clinic, Hospital for Tropical Diseases, University London Colleges NHS Foundation Trust, Mortimer Market, London WC1E 6JB, UK.

Background: Diagnosis of malaria relies on parasite detection by microscopy or antigen detection; both fail to detect low-density infections. New tests providing rapid, sensitive diagnosis with minimal need for training would enhance both malaria diagnosis and malaria control activities. We determined the diagnostic accuracy of a new loop-mediated amplification (LAMP) kit in febrile returned travelers.

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