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Physical activity: benefit or weakness in metabolic adaptations in a mouse model of chronic food restriction?

Am J Physiol Endocrinol Metab

February 2015

University Lille (ULCO, USTL, Lille2), Lille, France; Development and Plasticity of Postnatal Brain, UMR 837 Institut National de la Sante et de la Recherche Medicale (INSERM), Lille, France;

In restrictive-type anorexia nervosa (AN) patients, physical activity is usually associated with food restriction, but its physiological consequences remain poorly characterized. In female mice, we evaluated the impact of voluntary physical activity with/without chronic food restriction on metabolic and endocrine parameters that might contribute to AN. In this protocol, FRW mice (i.

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