2 results match your criteria: "University Institute for Image-Guided Surgery[Affiliation]"
Comparative analysis of resuscitation using human serum albumin and crystalloids or 130/0.4 hydroxyethyl starch and crystalloids on skeletal muscle metabolic profile during experimental haemorrhagic shock in swine: A randomised experimental study.
Eur J Anaesthesiol
February 2017
From the Anesthesia and Intensive Care, Hôpital de Hautepierre, University Hospitals of Strasbourg (EN, JP, PD), EA 3072, Laboratoire de Physiologie, Fédération de Médecine Translationnelle, Strasbourg University (EN, MD, ALC, FS, JP, BG, PD), IHU-Strasbourg, University Institute for Image-Guided Surgery, Strasbourg, France (EN, MD, JP, PD), Department of Anesthesiology, Stony Brook University, Stony Brook, New York, USA (TJG), Biophysics and Nuclear Medicine, Hôpital de Hautepierre, University Hospitals of Strasbourg (F-MM, IJN) and ICube, University of Strasbourg/CNRS UMR 7357, Strasbourg, France (F-MM, IJN).
Background: Protection against acute skeletal muscle metabolic dysfunction and oxidative stress could be a therapeutic target in volume expansion for severely bleeding patients.
Objectives: This experimental pilot study in swine aims at comparing 130/0.4 hydroxyethyl starch (HES) with 4% albumin along with crystalloid perfusion for first-line volume expansion in haemorrhagic shock with a particular emphasis on oxidative stress and muscular mitochondrial function.
Metabolism-Guided Bowel Resection: Potential Role and Accuracy of Instant Capillary Lactates to Identify the Optimal Resection Site.
Surg Innov
October 2015
IRCAD Institute for Research Against Cancer of the Digestive System, Strasbourg, France IHU-Strasbourg, University Institute for Image-Guided Surgery, Strasbourg, France.
Background: Strip-based handheld devices can measure lactatemia on capillary blood obtained by needle puncturing. We aimed to assess the kinetic of bowel capillary lactates, metabolomics profiling, and mitochondria respiratory rate in a prolonged model of bowel hypoperfusion.
Materials And Methods: In 6 pigs, a 3- to 4-cm ischemic segment was created in 6 small bowel loops (total = 36 loops) by clamping the vascular supply, for a duration of 1 to 6 hours.