3,875 results match your criteria: "University Indianapolis.[Affiliation]"

Asymptomatic female softball pitchers have altered hip morphology and cartilage composition.

Sci Rep

January 2025

La Trobe Sport & Exercise Medicine Research Centre, School of Allied Health, Human Services and Sport, La Trobe University, Melbourne, VIC, Australia.

Few studies have explored hip morphology and cartilage composition in female athletes or the impact of asymmetric repetitive loading, such as occurs during softball pitching. The current cross-sectional study assessed bilateral bony hip morphology on computed tomography imaging in collegiate-level softball pitchers ('Pitch1', n = 25) and cross-country runners ('Run', n = 13). Magnetic resonance imaging was used to assess cartilage relaxation times in a second cohort of pitchers ('Pitch2', n = 10) and non-athletic controls ('Con', n = 4).

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Evaluating sex and line differences in successive negative contrast and ethanol consumption using alcohol preferring and high alcohol drinking rats.

Alcohol Clin Exp Res (Hoboken)

January 2025

Addiction Neuroscience, Department of Psychology and Indiana Alcohol Research Center, Indiana University Indianapolis, Indianapolis, Indiana, USA.

Background: The loss of a job or relationship are a couple of examples of unexpected reward loss. Life events, such as these can induce negative emotional reactions (e.g.

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Adolescence is characterized by heightened emotion dysregulation, impulsivity, and engagement in high-risk behaviors, such as substance use, violence, and unprotected sexual activity. Dialectical Behavioral Therapy for Adolescents (DBT-A) is an evidence-based intervention that targets emotion regulation and impulsivity among adolescents, proven effective at decreasing high-risk behaviors. However, limited research exists on adolescents' perceptions of DBT-A, particularly in schools.

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Comparative Foliar Atmospheric Mercury Accumulation across Functional Types in Temperate Trees.

Environ Sci Technol

January 2025

State Key Laboratory of Cryospheric Science and Frozen Soil Engineering, Northwest Institute of Eco-Environment and Resources, Chinese Academy of Sciences, Lanzhou 730000, China.

Vegetation assimilation of atmospheric gaseous elemental mercury (GEM) represents the largest dry deposition pathway in global terrestrial ecosystems. This study investigated Hg accumulation mechanisms in deciduous broadleaves and evergreen needles, focusing on how ecophysiological strategies─reflected by δC, δO, leaf mass per area, and leaf dry matter content-mediated Hg accumulation. Results showed that deciduous leaves exhibited higher total Hg (THg) concentrations and accumulation rates (THg), which were 85.

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Although cognitions have predicted COVID-19 protective behaviors in cancer populations, theory suggests that emotions may be more predictive of these behaviors. This study examined Health Belief Model (HBM) variables as correlates of COVID-19 protective behaviors in lung cancer patients and whether worry about COVID-19 was associated with these behaviors beyond the effects of HBM variables. From 2021 to 2022, 191 patients (62.

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Objectives: Examine the feasibility, acceptability, and preliminary effects of the Telephone Acceptance and Commitment Therapy Intervention for Caregivers (TACTICs) on dementia caregivers' anxiety, depression, caregiver burden, suffering, and anticipatory grief.

Method: A 2-arm pilot randomized trial with dementia caregivers ≥ 21 years old with clinically elevated anxiety or anxiety-related functional interference. Two cohorts were recruited at the beginning and end of the first year of the COVID-19 pandemic.

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Most activities of daily life involve some degree of coordinated, bimanual activity from the upper limbs. However, compared to single-handed movements, bimanual movements are processed, learned, and controlled from both hemispheres of the brain. Transcranial direct current stimulation (tDCS) is a non-invasive brain stimulation technique that enhances motor learning by modulating the activity of movement-associated brain regions.

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Background: Individuals with Sickle Cell Disease (SCD) are a minoritized and marginalized community that have disparate health outcomes as a result of systemic racism and disease-related stigma. The purpose of this study was to determine the psychosocial risk factors for families caring for children with SCD at a pediatric SCD center through use of the Psychosocial Assessment Tool (PAT), a validated caregiver-report screener.

Methods: The PAT was administered annually during routine clinical visits and scored by the SCD Social Worker to provide tailored resources to families.

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Purpose: Vascular impairments, including reduced capillary density (CD), impaired autoregulation capacity (Reg), and elevated intraocular pressure (IOP), have been identified as significant contributors to glaucomatous disease. This study implemented a theoretical model to quantify the impact of these impairments on retinal blood flow and oxygenation as intraluminal pressure (Pa) is varied.

Methods: A theoretical model of the retinal vasculature was used to simulate reductions in CD by 10% (early glaucoma) and 30% to 50% (advanced glaucoma), a range in autoregulation capacity from 0% (totally impaired) to 100% (totally functional), and normal (15 mm Hg) and elevated (25 mm Hg) levels of IOP.

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How humans perceive the texture of a surface can inform and guide how their interaction takes place. From grasping a glass to walking on icy steps, the information we gather from the surfaces we interact with is instrumental to the success of our movements. However, the hands and feet differ in their ability to explore and identify textures.

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Community isolation of patients with communicable infectious diseases limits spread of pathogens but our understanding of isolated patients' needs and challenges is incomplete. Rwanda deployed a digital health service nationally to assist public health clinicians to remotely monitor and support SARS-CoV-2 cases via their mobile phones using daily interactive short message service (SMS) check-ins. We aimed to assess the texting patterns and communicated topics to better understand patient experiences.

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Guided by the integrated behavioral model, the authors interviewed 14 Black breast cancer survivors ( = 14) who had participated in a breast cancer clinical trial. This study aimed to better understand what may motivate Black women to engage in medical research and decide to participate in medical research. Findings revealed that Black women's altruistic desires to serve others and their communities are greatly influenced by the need to leave a "legacy" of better treatment for other Black women.

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Achieving Data Modernization Requires Addressing the Digital Divide Among Local Health Departments.

J Public Health Manag Pract

November 2024

Author Affiliations: Department of Health Policy & Management, Fairbanks School of Public Health, Indiana University Indianapolis, Indianapolis, Indiana (Mr Ghimire and Dr Dixon); Center for Biomedical Informatics, Regenstrief Institute, Indianapolis, Indiana(Dr Dixon).

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Mental Health Utilization Among Transgender Veterans.

JAMA Netw Open

January 2025

VA Center for Health Information and Communication, US Department of Veterans Affairs, Veterans Health Administration, Health Systems Research CIN 13-416, Richard L. Roudebush VA Medical Center, Indianapolis, Indiana.

Importance: Compared with cisgender (CG) individuals, transgender and gender-diverse (TGD) individuals experience substantial social and economic disparities that can result in adverse mental health consequences. It is critical to understand potential barriers to care and to address the causes of the disparities in the future.

Objective: To characterize mental health care utilization among TGD veterans with depression.

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Women are widely assumed to be more talkative than men. Challenging this assumption, Mehl et al. (2007) provided empirical evidence that men and women do not differ significantly in their daily word use, speaking about 16,000 words per day (WPD) each.

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Effects of Long-Term Storage on the Isotopic Compositions of Different Types of Environmental Waters.

Rapid Commun Mass Spectrom

April 2025

Department of Earth and Environmental Sciences, Indiana University Indianapolis, Indianapolis, Indiana, USA.

Rationale: Fog, dew, and rain are crucial for sustaining ecosystem functions, especially in water-limited regions. However, they are subject to isotopic changes during storage due to their usual small sample volumes and inherent sensitivity to atmospheric particulates. Understanding long-term storage effects on these water samples is essential for ensuring isotopic integrity.

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Correlates of Perceived Illness Severity and Terminality in Advanced Lung and Prostate Cancer.

J Pain Symptom Manage

January 2025

Department of Psychology (M.D.P, E.S., E.K., C.E.M.), Indiana University Indianapolis, Indianapolis, Indiana, USA. Electronic address:

Context: While prognostic awareness has been commonly assessed as perceived illness terminality in patients with advanced cancer, both perceptions of illness severity and terminality may be correlated with symptom burden and quality of life.

Objectives: The present study examined physical and psychological symptoms, quality of life, and smoking status in relation to perceived illness severity and terminality in patients with advanced, inoperable lung and prostate cancer.

Methods: Patients (N=198) were recruited from hospitals in the midwestern U.

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Recurrent activity propagates through labile ensembles in macaque dorsolateral prefrontal microcircuits.

Curr Biol

January 2025

Department of Pharmacology, Vanderbilt Brain Institute, Vanderbilt Center for Addiction Research, Vanderbilt University, Nashville, TN 37232, USA; Department of Anatomy, Cell Biology, & Physiology, Indiana University School of Medicine, Indianapolis, IN 46202, USA. Electronic address:

Human and non-human primate studies clearly implicate the dorsolateral prefrontal cortex (dlPFC) as critical for advanced cognitive functions. It is thought that intracortical synaptic architectures within the dlPFC are the integral neurobiological substrate that gives rise to these processes. In the prevailing model, each cortical column makes up one fundamental processing unit composed of dense intrinsic connectivity, conceptualized as the "canonical" cortical microcircuit.

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Diet is one of a limited set of key ecological parameters defining primate species. A detailed understanding of dental functional correlates with primate diet is a key component for accurate dietary inference in fossil primates. Although considerable effort has been devoted to understanding post-canine dental function, incisor function remains poorly understood.

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Reduction-oxidation factor-1 or apurinic/apyrimidinic endonuclease 1 (Ref-1/APE1) is a crucial redox-sensitive activator of transcription factors such as NF-κB, HIF-1α, STAT-3 and others. It could contribute to key features of ocular neovascularization including inflammation and angiogenesis; these underlie diseases like neovascular age-related macular degeneration (nAMD). We previously revealed a role for Ref-1 in the growth of ocular endothelial cells and in choroidal neovascularization (CNV).

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Pilot Testing and Validation of an Educational Game on Transportation Challenges for Mobility Device Users.

Disabilities (Basel)

December 2024

Human Engineering Research Laboratories, Department of Veterans Affairs Pittsburgh Healthcare System, University of Pittsburgh, Pittsburgh, PA 15206, USA.

Despite the increasing use of assistive mobility devices, practical education to navigate real-world ground transportation barriers is lacking. The educational board game, called HERL-Town, was developed to teach safe and effective navigation for mobility device users (MDUs) in the community. The study examined the initial validity, reliability, and overall quality of HERL-Town as an educational tool for overcoming transportation barriers in real-world environments.

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Article Synopsis
  • Pulmonary vascular disease is a complex condition that can arise from various underlying health issues, and precision medicine is becoming a viable approach for its diagnosis and treatment.
  • The 2023 Grover Conference Series focused on advancing our understanding of precision medicine's role in pulmonary vascular disease by examining clinical phenotypes, genetics, epigenetics, biomarker discovery, and the implications for clinical trials and care.
  • Despite promising developments, there are still challenges in effectively implementing these advanced tools in patient care.
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Optimizing recovery in first-episode psychosis: A systematic review of psychosocial interventions.

Schizophr Res

January 2025

Department of Psychology, Indiana University Indianapolis, 402 N. Blackford St., Indianapolis, IN 46202, USA. Electronic address:

This systematic review evaluates the efficacy of psychosocial interventions for individuals experiencing first-episode psychosis (FEP) across multiple recovery outcomes. Drawing from 35 studies, the analysis synthesizes evidence on symptom reduction, social and role functioning improvement, continuity of care, hospitalization rates, and other psychological outcomes. Regarding symptom reduction, specialized FEP programs demonstrated decreases across positive, negative, and general symptoms.

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This study investigated the effects of resin composites (RCs) containing surface pre-reacted glass ionomer (S-PRG) filler on the dentin microtensile bond strength (μTBS) of HEMA-free and HEMA-containing universal adhesives (UAs). Water sorption (WS) and solubility (SL), degree of conversion (DC), and ion release were measured. The UAs BeautiBond Xtreme (BBX; 0% HEMA), Modified Adhesive-1 (E-BBX1; 5% HEMA), Modified Adhesive-2 (E-BBX2; 10% HEMA), and two 2-step self-etch adhesives (2-SEAs): FL-BOND II (FBII; with S-PRG filler) and silica-containing adhesive (E-FBII) were used.

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