Perception of Healthcare Workers on the Integration of Electronic Health Records in Primary Health Centers in Nigeria.

The study aim was to assess the perception of healthcare workers in primary healthcare centers toward the integration of EHRs into practice. A descriptive cross-sectional design was used. Out of 10 primary healthcare centers, 120 healthcare workers were selected by simple random sampling, whereas 109 questionnaires were fit for analysis.

Understanding how different modification processes affect the physiochemical, functional, thermal, morphological structures and digestibility of cardaba banana starch.

In this study, starch was isolated from cardaba banana starch and was subjected to modification by heat-moisture treatment, citric acid, octenyl succinic anhydride, and sodium hexametaphosphate. Both the native and modified cardaba banana starches were examined for chemical, functional, pasting, thermal, morphological, structural, and antioxidant properties, as well as in vitro starch digestibility. Modification significantly influenced the properties of the cardaba banana starch.

Nigeria's financing of health care during the COVID-19 pandemic: Challenges and recommendations.

An analysis of the financing of Nigeria's health-care system in response to coronavirus disease 2019 (COVID-19) pandemic was conducted. Nigeria projected that it would need US$330 million to control its COVID-19 pandemic. However, it raised more than US$560.

Determinants of late detection and advanced-stage diagnosis of breast cancer in Nigeria.

Objective: To describe the risk factors for late detection and advanced-stage diagnosis among patients who detected their BC early.

Method: Using secondary data, we analyzed the impact of socio-demographic factors, premorbid experience, BC knowledge, and health-seeking pattern on the risk of late detection and advanced-stage diagnosis after early BC detection. Test of statistical significance in SPSS and EasyR was set at 5% using Sign-test, chi-square tests (of independence and goodness of fit), odds ratio, or risk ratio as appropriate.

COVID-19 and Antimicrobial Resistance: A Review.

As the world continues to respond to the coronavirus pandemic (COVID-19), there is a larger hidden threat of antimicrobial resistance (AMR) lurking behind. AMR remains worrisome in that the pathogens causing resistant infections to thrive in hospitals and medical facilities, putting all patients at risk, irrespective of the severity of their medical conditions, further compounding the management of COVID-19. This study aims to provide overview of early findings on COVID-19 and AMR as well as to provide recommendations and lesson learned toward improving antimicrobial stewardship.

Purification and erythrocyte-membrane perturbing activity of a ketose-specific lectin from seeds.

This study purified a hemagglutinating protein (MoL) from seed, and investigated its hemolytic activity. Molecular weight and stability of MoL were also determined. Modification of some amino acid residues was carried out and the effect on MoL hemagglutinating activity determined.

Enhancing flowering plant functional richness improves wild bee diversity in vineyard inter-rows in different floral kingdoms.

Wild bees are threatened by multiple interacting stressors, such as habitat loss, land use change, parasites, and pathogens. However, vineyards with vegetated inter-rows can offer high floral resources within viticultural landscapes and provide foraging and nesting habitats for wild bees. Here, we assess how vineyard management regimes (organic vs.

Effectiveness of Triclosan Coated Suture for Subcutaneous Wound Closure in Preventing Surgical Site Infection following Mesh Repair of Inguinal Hernia: A Pilot Study.

Background: The role of prophylactic antibiotics in mesh repair of inguinal hernia is controversial and often based on institutional policies. Surgical site infection rate from earlier studies in Nigeria justifies the continued use of prophylactic antibiotics during hernia repair. With increased use of antibiotics comes the challenge of antibiotic resistance and toxicity.

Climate change adaptation strategies by smallholder farmers in Nigeria: does non-farm employment play any role?

Non-farm employment in agrarian communities in developing countries has received a lot of attention. However, its role in implementing climate change adaptation strategies is rarely discussed. This study employs a cross-sectional data to examine whether rural households in Southwest Nigeria are increasing the extent of climate change adaptation practices through their participation in non-farm employment.

Household food security and the COVID-19 pandemic in Nigeria.

Pivotal to human development and the sustainable development goals is food security, which remains of substantial concern globally and in Nigeria, particularly during the COVID-19 pandemic despite various palliatives and intervention initiatives launched to improve household welfare. This study examined the food security status of households during the pandemic and investigated its determinants using the COVID-19 National Longitudinal Phone Survey (COVID-19 NLPS). In analysing the data, descriptive statistics, bivariate as well as multivariate analysis were employed.

Moderated mediation roles of social connectedness and optimism on emotional intelligence and life satisfaction.

The processes and circumstances underlying the association between emotional intelligence and life satisfaction were investigated among rural older adults. The factor structure of the measures was also assessed to determine their capacity and suitability for use. Participants were 1053 (639 males and 414 females) older adults with a mean age of 71.

Antioxidant activity of the simulated gastro-intestinal digestion hydrolysate of two edible Nigerian marine molluscs: var radula (L.) and (M.).

The multifunctional nature of antioxidant peptides makes them more attractive candidates as dietary ingredients in health maintenance. Therefore, food protein-derived antioxidant peptides are continuously investigated. This study investigated the antioxidant properties of hydrolysate and ultrafiltered peptide fractions of and var radula-two commonly consumed marine molluscs known as periwinkles in southern Nigeria.

Data on pilot assessment of efficacy of artemether lumefantrine when co-administered with ciprofloxacin in malaria-typhoid co-infected patients.

Malaria -typhoid co-infection is associated with poverty and underdevelopment with significant morbidity and mortality with similarities in clinical features of the two diseases that often result in misdiagnosis and mistreatment of the febrile patients. The Co-administration of artemether lumefantrine (AL) with ciprofloxacin as treatment for malaria-typhoid co-infection is common in Nigeria and this increases risk of pharmacokinetic drug-drug interaction since ciprofloxacin is an inhibitor of CYP3A4 that metabolizes AL. In an open-label prospective three arm design with registration pactr201909811770922, one hundred and nineteen (119) febrile volunteers comprising 55 males and 64 females were distributed into three oral treatment regimen groups.

Synthesis of new pyridines with sulfonamide moiety a cooperative vinylogous anomeric-based oxidation mechanism in the presence of a novel quinoline-based dendrimer-like ionic liquid.

In the present study, we reported the synthesis of a novel quinoline-based dendrimer-like ionic liquid. After characterization of the mentioned ionic liquid with suitable techniques such as Fourier transform infrared spectroscopy (FT-IR), energy dispersive X-ray spectroscopy (EDX), elemental mapping, thermogravimetric analysis (TGA) and derivative thermogravimetry (DTG), its catalytic performance was investigated in the synthesis of new pyridines with sulfonamide moiety a cooperative vinylogous anomeric-based oxidation mechanism under mild reaction conditions. All target molecules were achieved in short reaction times and high yields.

Chromeno-carbonitriles as corrosion inhibitors for mild steel in acidic solution: electrochemical, surface and computational studies.

Three novel -hydrospiro-chromeno-carbonitriles namely, 2-amino-7,7-dimethyl-1',3',5-trioxo-1',3',5,6,7,8-hexahydrospiro[chromene-4,2'-indene]-3-carbonitrile (INH-1), 3-amino-7,7-dimethyl-2',5-dioxo-5,6,7,8-tetrahydrospiro[chromene-4,3'-indoline]-2-carbonitrile (INH-2) and 3'-amino-7',7'-dimethyl-2,5'-dioxo-5',6',7',8'-tetrahydro-2-spiro[acenaphthylene-1,4'-chromene]-2'-carbonitrile (INH-3) were synthesized using the principles of green chemistry and applied as corrosion inhibitors for mild steel in acidic medium using computational simulations and experimental methods. Experimental and computational studies revealed that inhibition effectiveness of the INHs followed the sequence: INH-3 (95.32%) > INH-2 (93.

Synthesis and structures of divalent Co, Ni, Zn and Cd complexes of mixed dichalcogen and dipnictogen ligands with corrosion inhibition properties: experimental and computational studies.

The structural and corrosion inhibition properties of four different transition-metal complexes of heteroleptic S-donor atom dithiophosphonate and N-donor atom phenanthroline ligands are reported. Full structural characterization of the Co, Ni, Zn and Cd complexes was achieved with the aid of single-crystal X-ray crystallography. Structural elucidation revealed the formation of a 4-coordinate Zn(ii) complex, and 6-coordinate Ni(ii) and Cd(ii), as well as a novel dithiophosphonato Co(ii) complex.

Gluten-free cookies with low glycemic index and glycemic load: optimization of the process variables via response surface methodology and artificial neural network.

This research investigates the effect of baking temperature and time on the resistant starch (RS), glycemic index (GI) and glycemic load (GL) of gluten-free cookies, optimized the processing parameter using a chemometrics approach of response surface methodology (RSM) and artificial neural network (ANN). The in-vitro starch digestibility of the formulated cookies exhibited a monophasic starch digestogram. Increase in resistant starch, and a decrease in the predicted GI of the cookies, was associated with low temperature and high baking time.

Identifying heterotic groups and testers for hybrid development in early maturing yellow maize () for sub-Saharan Africa.

Identification of heterotic groups and efficient testers, which are important prerequisites for the development of outstanding hybrids, has been a major challenge to its success, especially for early and extra-early germplasm. This study was carried out to (a) identify the most efficient heterotic grouping method for classifying a set of inbred lines and (b) determine the efficiency of testers in classifying inbred lines into heterotic groups. A total of 205 hybrids obtained by crossing 41 inbred lines with five standard testers were evaluated together with five hybrid checks under drought, low soil nitrogen (N), -infested and optimal environments in Nigeria between 2014 and 2016.

Genetic studies of extra-early provitamin-A maize inbred lines and their hybrids in multiple environments.

Vitamin A deficiency, drought, low soil nitrogen (low-N), and parasitism of maize ( L.) cause malnutrition and food insecurity in sub-Saharan Africa. The objectives of this study were to determine combining abilities of extra-early provitamin A (PVA) lines, classify them into heterotic groups (HGs), identify testers, and determine yield stability of hybrids under contrasting environments in two trials.

Efficacy of a natural coagulant protein from (Lam) seeds in treatment of Opa reservoir water, Ile-Ife, Nigeria.

Health related and environmental side effects associated with conventional chemical coagulants used in water treatment has prompted the search for natural alternatives, especially of plant origin. This study investigated the water coagulation activities of a purified protein from seeds on the water from Opa reservoir of Obafemi Awolowo University, Ile-Ife. coagulant protein (MoCP) was purified via ion exchange and gel filtration chromatography respectively.

Explanations around physical abuse, neglect and preventive strategies among older Yoruba people (60+) in urban Ibadan Southwest Nigeria: A qualitative study.

Older people's views, experiences and explanations on abuse and neglect in later life is marginal in the literature. With more cases of physical abuse and neglect in old age in sub-Saharan Africa, this study explored the views and positions of older people and community stakeholders like religious leaders on why physical elder abuse and neglect and preventive measures within community settings in Nigeria. An exploratory research design that consisted of two focus group discussions with older Yoruba men and women (60+) and six semi-structured interviews with religious leaders (Christianity, Islam, and Traditional) guided the study.

normalized cimetidine-induced pituitary-testicular dysfunction: Relevance in nutraceutical therapy.

Background: The increasing incidence of chemically induced infertility is both a social threat and a threat to the continuation of life itself. Treatment or management therapy is often expensive. This study investigated the effects of acetone extract of a local plant () in a Wistar rat model of cimetidine-induced pituitary-testicular dysfunction.

Acridine-based thiosemicarbazones as novel inhibitors of mild steel corrosion in 1 M HCl: synthesis, electrochemical, DFT and Monte Carlo simulation studies.

Electrochemical, surface morphology, density functional theory and Monte Carlo simulation methods were employed in investigating the effects of (2,2')-2,2'-(3,3,6,6-tetramethyl-9-phenyl-3,4,6,7-tetrahydroacridine-1,8(2,5,9,10)-diylidene)bis(-phenylhydrazinecarbothioamide) (IAB-NP), (2,2')-2,2'-(3,3,6,6-tetramethyl-9-phenyl-3,4,6,7-tetrahydroacridine-1,8(2,5,9,10)-diylidene)bis(-(2,4-difluorophenyl)hydrazinecarbothioamide)IAB-ND) and (2,2')-2,2'-(3,3,6,6-tetramethyl-9-phenyl-3,4,6,7-tetrahydroacridine-1,8(2,5,9,10)-diylidene)bis(-(2-fluorophenyl) hydrazinecarbothioamide) (IAB-NF) on mild steel corrosion in 1 M HCl solution. From the studies, compounds IAB-NP, IAB-ND and IAB-NF inhibit mild steel corrosion in the acid and the protection efficiencies were found to increase with the increase in concentration of each compound. At the optimum inhibitor concentration of 1.