3 results match your criteria: "University Hospitals of Leuven and KU Leuven[Affiliation]"
Bone Marrow Transplant
September 2022
Department of Internal Medicine III, Faculty of Medicine, University Hospital Regensburg, Regensburg, Germany.
Bone Marrow Transplant
January 2022
Section of Hematology, Centre Hospitalier Universitaire de Liège, Université de Liège, Liège, Belgium.
Eur J Nucl Med Mol Imaging
September 2019
Division of Nuclear Medicine and Molecular Imaging, University Hospitals of Leuven and KU Leuven, Leuven, Belgium.
Purpose: The P2X7 receptor (P2X7R) is an ATP-gated ion channel predominantly expressed on activated microglia and is important in neurodegenerative diseases including Parkinson's disease (PD). In this first-in-human study, we investigated [C]JNJ54173717 ([C]JNJ717), a selective P2X7R tracer, in healthy volunteers (HV) and PD patients. Biodistribution, dosimetry, kinetic modelling and short-term test-retest variation (TRV), as well as possible genotype effects, were investigated.
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