3,405 results match your criteria: "University Hospitals of Leicester NHS Trust[Affiliation]"
Shoulder Elbow
July 2024
Trauma & Orthopaedic Surgery Department, Leicester Royal Infirmary, Leicester, UK.
Background: Shoulder range of motion (ROM) is traditionally measured using universal goniometry. However, novel devices to measure shoulder ROM digitally are becoming increasingly available. We aimed to synthesise the current evidence to answer: 1) what technologies are currently in use? 2) Are they reliable? 3) How do they compare to goniometry?
Methods: Systematic review of the literature was conducted according to PRISMA guidelines.
HIV Med
December 2024
Department of Infection and HIV Medicine, University Hospitals of Leicester NHS Trust, Leicester, UK.
Ther Adv Musculoskelet Dis
September 2024
University Hospitals of Leicester NHS Trust, Leicester, UK.
Cureus
August 2024
Acute Medicine, University Hospitals of Leicester NHS Trust, Leicester, GBR.
Discitis in children is uncommon, typically occurring between the ages of two and eight years. The etiology is not established, but it is generally considered a bacterial infection. Symptoms vary with age but commonly include irritability, refusal to walk, and back pain.
View Article and Find Full Text PDFBr J Surg
August 2024
Liverpool Centre for Cardiovascular Sciences, Liverpool Heart and Chest Hospital, Liverpool, UK.
EClinicalMedicine
September 2024
Nottingham Centre for Public Health and Epidemiology, Lifespan and Population Health, School of Medicine, University of Nottingham, Nottingham, United Kingdom.
Background: Antimicrobial resistance (AMR) is a critical global health concern. A previous systematic review showed that migrants in Europe are at increased risk of AMR. Since the COVID-19 pandemic there have been rapid changes in patterns of antibiotic use, AMR, and migration.
View Article and Find Full Text PDFAngiology
September 2024
Keele Cardiovascular Research Group, Centre for Prognosis Research, Institute for Primary Care and Health Sciences, Keele University, Keele, UK.
Patients with lower socioeconomic status (SES) have poorer outcomes following acute myocardial infarction (AMI) than patients with higher SES; however, how sex modifies socioeconomic differences is unclear. Using the United Kingdom (UK) Myocardial Ischaemia National Audit Project (MINAP) registry, alongside Office of National Statistics (ONS) mortality data, we analyzed 736,420 AMI patients between 2005 and 2018, stratified by Index of Multiple Deprivation (IMD) score Quintiles (most affluent [Q1] to most deprived [Q5]). There was no significant difference in probability of in-hospital mortality in our adjusted model according to sex.
View Article and Find Full Text PDFJ Med Virol
September 2024
Department of Respiratory Sciences, University of Leicester, Leicester, UK.
HIV Med
January 2025
SHARE Collaborative, Queen Mary University of London, London, UK.
Br J Surg
August 2024
Department of Cardiovascular Sciences, University of Leicester, NIHR Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, UK.
Clin Res Hepatol Gastroenterol
October 2024
CRNH, Université Clermont Auvergne, AME2P, Clermont-Ferrand, France; International Research Chair Health in Motion, Clermont Auvergne University Foundation, Clermont-Ferrand, France. Electronic address:
Eur J Prev Cardiol
January 2025
Division of Sports and Exercise Medicine, Department of Sport, Exercise and Health, University of Basel, 4052 Basel, Switzerland.
Aims: To investigate how physical activity (PA) volume, intensity, duration, and fragmentation are associated with the risk of all-cause and cardiovascular disease mortality. To produce centile curves for PA volume and intensity representative of US adults.
Methods And Results: This study is based on the observational 2011-2014 National Health and Nutrition Examination Survey (NHANES).
BMC Nephrol
September 2024
Leicester Diabetes Centre, University Hospitals of Leicester NHS Trust, Leicester, England.
Background: National guidance recognises the key role of rehabilitation in improving outcomes for people living with chronic kidney disease. Implementation of this guidance is reliant upon an adequate and skilled rehabilitation workforce. Data relating to this is currently lacking within the UK.
View Article and Find Full Text PDFIntensive Care Med
November 2024
Wolfson Palliative Care Research Centre, Hull York Medical School, University of Hull, Hull, UK.
Purpose: The importance and effectiveness of palliative care (PC) in intensive care units (ICU) are known. Less is known about the implementation and integration of ICU-based PC interventions. This systematic review aims to use a modified implementation research logic model (IRLM) to identify, map, and synthesise evidence on implementation of ICU-PC (primary and/or specialist) interventions.
View Article and Find Full Text PDFiScience
September 2024
School of Engineering, University of Warwick, Coventry, UK.
Diagnosis of respiratory tract infections (RTIs), especially in primary care, is typically made on clinical features and in the absence of quick and reliable diagnostic tests. Even in secondary care, where diagnostic microbiology facilities are available, these tests take 24-48 h to provide an indication of the etiology. This multicentre study used a portable gas chromatography-ion mobility spectrometer (GC-IMS) for the diagnosis of bacterial RTIs.
View Article and Find Full Text PDFRheumatol Int
November 2024
Department of Rheumatology, University Hospitals of Leicester NHS Trust, Leicester, UK.
Eur J Vasc Endovasc Surg
September 2024
Department of Cardiovascular Sciences, University of Leicester, Leicester, UK; Leicester Vascular Institute, University Hospitals of Leicester NHS Trust, Leicester, UK; National Institute for Health Research Leicester Biomedical Research Centre - The Glenfield Hospital, Leicester, UK.
Objective: Patient characteristics and patterns of disease in chronic limb threatening ischaemia (CLTI) have markedly changed in recent years. Urgent specialist referral and timely revascularisation are recommended in international guidelines. UK guidelines now recommend revascularisation within five days of referral for inpatients and two weeks in outpatients.
View Article and Find Full Text PDFArch Dis Child
November 2024
Emergency Department, Bristol Royal Hospital for Children, Bristol, UK.
Perfusion
September 2024
Department of Cardiovascular Sciences, University of Leicester, Leicester, UK.
Nat Rev Gastroenterol Hepatol
October 2024
Diabetes Research Centre, College of Life Sciences, University of Leicester, Leicester, UK.
Sci Rep
September 2024
King's College London, St John's Institute of Dermatology, 9Th Floor, Tower Wing, Guy's Hospital, Great Maze Pond, London, SE1 9RT, UK.
Ocul Immunol Inflamm
December 2024
St Paul's Eye Unit, Liverpool University Hospitals NHS Trust, Liverpool, UK.
Purpose: Ibrutinib is an irreversible Bruton's tyrosine kinase inhibitor that disrupts B-cell receptor signalling. It is licensed for treatment of low-grade B-cell malignancies, including chronic lymphocytic leukaemia, mantle cell lymphoma and lymphoplasmacytic lymphoma. A few case reports in the literature suggest that uveitis may be a side effect of ibrutinib treatment.
View Article and Find Full Text PDFAnn Med Surg (Lond)
September 2024
Neuromuscular Research Center, Department of Neurology, Shariati Hospital.
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by progressive loss of upper and lower motor neurons. Biomarkers are needed to improve diagnosis, gauge progression, and evaluate treatment. Diffusion tensor imaging (DTI) is a promising biomarker for detecting microstructural alterations in the white matter tracts.
View Article and Find Full Text PDFBr J Dermatol
November 2024
Clinical Standards Unit, British Association of Dermatologists, Willan House, London W1T 5HQ, UK.