946 results match your criteria: "University Hospitals Plymouth[Affiliation]"
BMJ Mil Health
January 2025
Emergency Department, Derriford Hospital, Plymouth, UK
The traditional approach to resuscitating injured women of childbearing potential (WCBP) with an unknown RhD type is to transfuse RhD-negative blood products. This is to prevent alloimmunisation to the RhD antigen and ultimately prevent haemolytic disease of the fetus and newborn (HDFN) in future pregnancies should she survive. RhD-negative blood products are scarce in both military and civilian blood stocks.
View Article and Find Full Text PDFIntroduction: The ability to admit patients to enhanced or critical care may be limited by bed availability. In a network with low provision of critical and enhanced care beds, we aimed to assess the proportion of patients having surgery with moderate (1%-< 5%) or high (≥ 5%) predicted risk of 30-day postoperative mortality and their postoperative care location. We also aimed to study referral and admission outcomes to critical care.
View Article and Find Full Text PDFPLoS One
January 2025
Department of Diagnostic and Interventional Radiology, University Hospitals Plymouth NHS Trust, Plymouth, United Kingdom.
Background: The spleen is commonly injured in trauma and this may be managed with a conservative approach, embolisation or splenectomy. There is uncertainty how splenic embolisation fits into the treatment paradigm and the delivery of IR services remains variable.
Aims And Objectives: The primary objectives are to determine if service design significantly affects splenic embolisation (SE) rates in AAST grade 2-5 acute traumatic splenic injuries (ATSI) across the Major Trauma Centres (MTCs) in England and to determine if variation in treatment affects SE outcomes in ATSI.
Scand J Trauma Resusc Emerg Med
January 2025
Faculty of Pre-Hospital Care, Royal College of Surgeons Edinburgh, Edinburgh, UK.
Background: Road traffic injury is the leading cause of death among young people globally, with motor vehicle collisions often resulting in severe injuries and entrapment. Traditional extrication techniques focus on limiting movement to prevent spinal cord injuries, but recent findings from the EXIT project challenge this approach. This paper presents updated recommendations from the Faculty of Pre-Hospital Care (FPHC) that reflect the latest evidence on extrication practices.
View Article and Find Full Text PDFBackground: Acquired angioedema due to C1-inhibitor deficiency (AAE-C1-INH) is very rare compared to its prototype, hereditary angioedema. An updated characterisation of the AAE-C1-INH cohort in UK is required to inform management.
Objectives: To describe the disease burden of AAE-C1-INH, long-term prophylaxis (LTP) and the clinical, immunochemical and treatment profiles of AAE-associated diseases in UK.
Cureus
December 2024
Colorectal Surgery, University Hospitals Plymouth NHS Trust, Plymouth, GBR.
Adult intussusception is an uncommon condition that constitutes a small percentage of cases of bowel obstruction in adults. Unlike its paediatric counterpart, it is often linked to an underlying pathology, necessitating surgical interventions for diagnosis and treatment. This report discusses a case involving a 54-year-old woman who presented with symptoms of small bowel obstruction, including abdominal pain, nausea, and constipation, along with a one-month history of weight loss.
View Article and Find Full Text PDFResuscitation
December 2024
University Hospitals Birmingham NHS Foundation Trust, Birmingham Heartlands Hospital B9 5SS UK; Warwick Clinical Trials Unit, University of Warwick, Coventry, CV4 7AL.
Objective: To examine maternal and neonatal outcomes following Resuscitative Hysterotomy for out of hospital cardiac arrest (OHCA) and to compare with timing from cardiac arrest to delivery.
Methods: The review was registered with PROSPERO (CRD42023445064). Studies included pregnant women with out of hospital cardiac arrest and resuscitative hysterotomy performed (in any setting) during cardiac arrest.
Clin Radiol
December 2024
Department of Radiology, University Hospitals Dorset NHS Foundation Trust, Poole, BH15 2JB, UK.
Clinical and interventional radiology services play a vital role in the provision of modern healthcare, but there is a widening gap between the capacity of the imaging workforce and increasing demand. In recent years there has been a programme of training expansion in England supported by tariff level funding from NHS England (Workforce Training and Education Directorate), enhancing long-term radiology workforce sustainability and bringing quality benefits for patients, departments, and trusts. Expansion is a multifaceted and challenging process in the current NHS climate, involving coordination of funding, capacity, and sustained educational quality.
View Article and Find Full Text PDFJ Am Geriatr Soc
December 2024
Brookdale Department of Geriatrics and Palliative Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Introduction: The COVID-19 pandemic accelerated the shift from in-person to virtual recruitment, prompting residency and fellowship programs to adopt innovative strategies, such as leveraging social media platforms to attract applicants and enhance visibility. Our aim was to identify and describe the presence of U.S.
View Article and Find Full Text PDFBMJ Open
December 2024
Emergency Department, Lausanne University Hospital, Lausanne, Switzerland.
Objectives: To develop and validate a simplified Bleeding Audit Triage Trauma (sBATT) score for use by lay persons, or in areas and environments where physiological monitoring equipment may be unavailable or inappropriate.
Design: The sBATT was derived from the original BATT, which included prehospital systolic blood pressure (SBP), heart rate, respiratory rate, Glasgow Coma Scale (GCS), age and trauma mechanism. Variables suitable for lay interpretation without monitoring equipment were included (age, level of consciousness, absence of radial pulse, tachycardia and trapped status).
Cureus
November 2024
Diabetes and Endocrinology, University Hospitals Plymouth National Health Service (NHS) Trust, Plymouth, GBR.
Primary hyperparathyroidism (PHPT) typically presents with a spectrum of symptoms, including neuropsychiatric manifestations such as anxiety, depression, confusion, and, in severe cases, coma. While psychiatric symptoms are not uncommon in PHPT, acute psychosis is a rare presentation. In such cases, immediate control of serum calcium levels is crucial, and emergency parathyroidectomy may be required if medical management alone fails to control hypercalcemia.
View Article and Find Full Text PDFCureus
November 2024
General Internal Medicine, University Hospitals Plymouth NHS Trust, Plymouth, GBR.
Artificial intelligence (AI) technologies (natural language processing (NLP), speech recognition (SR), and machine learning (ML)) can transform clinical documentation in healthcare. This scoping review evaluates the impact of AI on the accuracy and efficiency of clinical documentation across various clinical settings (hospital wards, emergency departments, and outpatient clinics). We found 176 articles by applying a specific search string on Ovid.
View Article and Find Full Text PDFJ Clin Med
December 2024
Royal Brompton Hospital, Part of Guy's and St. Thomas' NHS Foundation Trust, London SW3 6NP, UK.
The epidemiological data regarding mortality rates of adults with sarcoidosis and non-ischemic cardiovascular disease (CVD) are limited. A retrospective observational analysis was conducted to identify trends and disparities related to sarcoidosis and non-ischemic cardiovascular disease mortality among the adult US population from 1999 to 2022. We used the Centers for Disease Control and Prevention (CDC) WONDER database to extract death certificate data for the adult US population (≥25 years).
View Article and Find Full Text PDFHeart Rhythm
December 2024
Myocardial Function Section, National Heart and Lung Institute, Imperial College London, London, United Kingdom; Cardiology Department, Hammersmith Hospital, Imperial College Healthcare NHS Trust, London, United Kingdom; Imperial Centre for Cardiac Engineering, Imperial College London, London, United Kingdom. Electronic address:
Indian J Orthop
December 2024
Department of Paediatric Trauma and Orthopaedics, Southampton Children's Hospital, Southampton, UK.
Background: Hip surgery is often necessary for children with severe neuromuscular disabilities to avoid chronic pain resulting from hip migration. This study correlated the Surgical Vulnerability Score (SVS), a novel measure of physiological reserve, with reconstructive hip surgery outcomes to improve shared surgical decision-making.
Materials And Methods: Sixty-eight cases performed by a single surgeon were retrospectively evaluated.
Am J Otolaryngol
December 2024
ENT Department, University Hospitals Plymouth NHS Trust, Plymouth, UK; Peninsula Medical School, University of Plymouth, Plymouth, UK.
Background & Purpose: Narrow Band Imaging (NBI), developed by Olympus Medical Systems, has played a role in diagnosing digestive tract lesions and cancers, diagnosing and characterizing bladder cancers during cystoscopy and in the diagnosis and management of Head and Neck cancers. We aim to explore the potential use of NBI in the diagnosis, management, and follow-up of sinonasal tumours.
Methods: We present a series of cases treated at our institution, where NBI played a crucial role in the diagnosis, surgical management, intraoperative decision-making, and follow-up.
J Intensive Care Soc
December 2024
Wellcome-Wolfson Institute for Experimental Medicine, Queen's University Belfast, Belfast, UK.
Background: Animal-assisted interventions (AAI) can provide psychological support to critical care patients during their intensive care unit (ICU) admission. However, there are currently no data on AAI services across UK ICUs. The current study therefore aims to (i) determine how many ICUs in the UK offer services, (ii) characterise available services and (iii) explore and review local documentation for service oversight.
View Article and Find Full Text PDFJ Fluoresc
December 2024
Faculty of Health, University Hospitals Plymouth NHS Trust, Plymouth, UK.
Indocyanine Green (ICG) fluorescence-guided surgery (I-FIGS) is increasingly being used in hepato-pancreatico-biliary (HPB) surgery. However, the true benefit of I-FIGS, the optimum dosing, and the timing of ICG administration still need to be determined. To conduct future research studies in the above areas, it is essential to understand the current I-FIGS practices among surgeons.
View Article and Find Full Text PDFCureus
November 2024
Radiology, University Hospitals Plymouth NHS Trust, Plymouth, GBR.
This is a case of a young lady who was admitted multiple times with complaints of inability to digest food and abdominal pain. She had nausea and vomiting for long periods and was unable to tolerate orally. As she was unable to tolerate oral feeding and losing weight, she was started on nasogastric feed (NG feed) and later percutaneous endoscopic gastrostomy (PEG) tube feeding because NG feed was uncomfortable for the patient and did not alleviate the problem.
View Article and Find Full Text PDFBr Paramed J
December 2024
Health Innovation South West.
Introduction: Unplanned out-of-hospital births (UOHBs) are associated with poorer outcomes for babies, especially those born prematurely. The current Newborn Life Support (NLS) course offered by Resuscitation Council UK (RCUK) is not designed to address the challenges associated with birth out of hospital. A new course was developed to address these challenges.
View Article and Find Full Text PDFBone Joint J
December 2024
Nottingham University Hospitals NHS Trust, Nottingham, UK.
J Laparoendosc Adv Surg Tech A
November 2024
Department of Hepatobiliary Surgery University Hospitals Plymouth NHS Trust, Plymouth, UK.
Laparoscopic cholecystectomy is one of the most common surgical procedures. Several techniques of ligating the cystic duct have been compared in randomized trials, but data on comparative effectiveness are missing. Our aim was to systematically review the literature and, if appropriate, synthesize the available evidence.
View Article and Find Full Text PDFWorld J Hepatol
November 2024
Microbiology Service, University Hospitals Plymouth NHS Trust, Plymouth PL6 8DH, United Kingdom.
Background: Spontaneous bacterial peritonitis (SBP) is one of the most important complications of patients with liver cirrhosis entailing high morbidity and mortality. Making an accurate early diagnosis of this infection is key in the outcome of these patients. The current definition of SBP is based on studies performed more than 40 years ago using a manual technique to count the number of polymorphs in ascitic fluid (AF).
View Article and Find Full Text PDFExp Clin Transplant
October 2024
From the Southwest Transplant Centre, University Hospitals Plymouth, National Health Service Trust, Plymouth, United Kingdom, and the University of Plymouth, Plymouth, United Kingdom.
Objectives: The implantable Doppler probe can monitor the patency of vascular anastomosis, thereby facilitating early detection of vascular thrombosis critical to reducing graft loss. In this study, we examined the effectiveness of this technology compared with standard clinical care in reducing thrombosis-related graft loss and the requirement for color duplex ultrasonography in the first 24 hours postoperatively by a medical literature search of the application of this technology in kidney transplantation.
Materials And Methods: We conducted a systematic search (January 15, 2024) of a wide range of experimental and observational studies that comprised kidney transplant recipients monitored with blood flow sensing technology (intervention group) and standard clinical care (control group).
Posterior reversible encephalopathy syndrome (PRES) is a reversible clinico-radiological condition primarily affecting the occipito-parietal regions. Thalami, brainstem, and cerebellar involvement with posterior fossa oedema are rare manifestations of this condition. We present the case of a 66-year-old male with a travel history to Thailand who was found collapsed on the floor two weeks after his return.
View Article and Find Full Text PDF