12 results match your criteria: "University Hospitals MacDonald Women's Hospital[Affiliation]"

Obstetrics and gynecology hospitalists play a vital role in reducing maternal morbidity and mortality by providing immediate access to obstetric care, especially in emergencies. Their presence in hospitals ensures timely interventions and expert management, contributing to better outcomes for mothers and babies. This proactive approach can extend beyond hospital walls through education, advocacy, and community outreach initiatives aimed at improving maternal health across diverse settings.

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Medical treatment with ulipristal acetate for uterine fibroids: Will it be resurrected?

Fertil Steril

July 2021

University Hospitals MacDonald Women's Hospital, Department of Obstetrics and Gynecology, Department of Reproductive Biology, School of Medicine Case Western Reserve University, Cleveland, Ohio.

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Preimplantation genetic testing for aneuploidy in uterus transplant patients.

Ther Adv Reprod Health

April 2021

Department of Obstetrics and Gynecology, Case Western Reserve University School of Medicine, University Hospitals MacDonald Women's Hospital, 11100 Euclid Avenue, Cleveland, OH 44106, USA.

Uterus transplantation is an emerging treatment for uterine factor infertility. In vitro fertilization with cryopreservation of embryos prior is required before a patient can be listed for transplant. Whether or not to perform universal preimplantation genetic testing for aneuploidy should be addressed by centers considering a uterus transplant program.

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Selective estrogen receptor modulators (SERMS): keys to understanding their function.

Menopause

October 2020

Departments of Obstetrics and Gynecology and Reproductive Biology, University Hospitals MacDonald Women's Hospital, Case Western Reserve University School of Medicine, Cleveland, OH.

Selective estrogen receptor modulators (SERMs) are an increasingly important therapeutic modality that are used by clinicians on a daily basis. Unfortunately, clinicians have a limited understanding regarding the underlying mechanism(s) of how SERMs function and their increasingly useful role in the treatment of estrogen-responsive target tissues such as the breast, bone, vagina, uterine endometrium, and brain. This review will provide a basic understanding of our current knowledge of SERM pharmacodynamics and will highlight the clinical applications of Food and Drug Administration-approved SERMs in the treatment of vasomotor symptoms, osteoporosis, genitourinary syndrome of menopause, infertility, and breast cancer and its prevention.

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Objective: We studied associations between social support, social network size, social strain, or stressful life events and risk of coronary heart disease (CHD) in postmenopausal women with type 2 diabetes.

Research Design And Methods: From the Women's Health Initiative, 5,262 postmenopausal women with type 2 diabetes at baseline were included. Cox proportional hazards regression models adjusted for demographics, depressive symptoms, anthropometric variables, and lifestyle factors were used to examine associations between social factors and CHD.

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Background: To evaluate the safety of immediate skin-to-skin contact (SSC) in vigorous late preterm neonates, where observation under radiant warmer is standard of care, in a prospective, randomized, controlled, and equivalence pilot study.

Methods: Singletons born vaginally at 35-36 6/7 weeks gestation were randomized to initiate immediate SSC or standard of care with continuous pulse oximeter monitoring for the first hour of life.

Results: Forty-seven dyads were randomized to SSC (n = 21) or radiant warmer (n = 26).

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Background: Breastfeeding and optimal birth spacing are associated with improved maternal and infant health outcomes worldwide. Provision of contraceptive advice that is aligned with recommendations for breastfeeding has potential to maximize maternal and infant health. Although there is broad agreement regarding the breastfeeding compatibility of specific postpartum contraceptive methods, it is not known whether maternal breastfeeding intention influences prenatal provider contraceptive counseling.

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Transgender health: Hormonal management at 50 years and beyond.

Maturitas

August 2019

University Hospitals MacDonald Women's Hospital, Department of Obstetrics and Gynecology, Case Western Reserve University School of Medicine, 11100 Euclid Avenue, Cleveland, OH 44106, United States. Electronic address:

This review discusses established transgender individuals on hormones who have reached their desired post-pubertal phenotype. Current guidelines have not clearly integrated specific considerations for the older population. This review focuses on changes in physiology with age, recommended maintenance therapy and safety evaluation to mitigate the risks of hormone therapy with a focus on the older population.

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In the United States, there are an increasing number of couples who are intentionally delaying child-bearing. As the average age of mothers continues to rise, more and more women are being faced with the difficulties of attempting conception at the various stages leading up to the menopausal transition. Not only do the chances of conception drastically decrease after the age of 40 years, but the probability of fetal loss (both early and late in pregnancy) significantly increases during this period as well.

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Alcohol and fertility: how much is too much?

Fertil Res Pract

July 2017

Department of Reproductive Biology - Case Western Reserve University School of Medicine, University Hospitals MacDonald Women's Hospital, 11100 Euclid Avenue, Cleveland, OH 44106 USA.

Alcohol use is prevalent in the United States. Given that a substantial portion of the drinking population is of reproductive age, it is not uncommon for couples who are attempting conception, or for women who are already pregnant, to be regularly consuming alcohol. Alcohol use is associated with multiple reproductive risks, including having a child with a Fetal Alcohol Spectrum Disorder, increased risk of fetal loss, and decreased chance of live birth.

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What is new in reproductive endocrinology?: best articles from the past year.

Obstet Gynecol

May 2012

University Hospitals/MacDonald Women's Hospital, Department of Obstetrics and Gynecology, Case Western Reserve University School of Medicine, Cleveland, Ohio 44106-5034, USA.

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Differential regulation of myometrial prostaglandin production by changes in length.

Am J Obstet Gynecol

February 2008

Department of Obstetrics and Gynecology, Case Western Reserve University School of Medicine, University Hospitals/MacDonald Women's Hospital, Cleveland, OH, USA.

Objective: The purpose of this study was to determine whether stretching and shortening of human myometrial strips alters prostaglandin production.

Study Design: We measured 6-keto prostaglandin F1alpha (PGF1alpha; a PGI2 metabolite) and PGF2alpha in the contraction baths of myometrial strips that were obtained at cesarean delivery from 5 term pregnant women. Fluid was collected after the stretching and after the strip lengths were decreased by 4%, 6%, or 8%.

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