1 results match your criteria: "University Hospitals Leuven and Experimental Laboratory Immunology[Affiliation]"

Overestimation of free light chain antigen excess rate.

Clin Chim Acta

April 2015

Laboratory Medicine, Department of Microbiology and Immunology, University Hospitals Leuven and Experimental Laboratory Immunology, KU Leuven, Herestraat 49, Leuven 3000, Belgium.

Background: Free light chains (FLC) are useful biomarkers for diagnosis and follow-up of plasma cell disorders. FLC quantification is encumbered by non-linearity and antigen excess (>4-fold difference between results obtained at the 2000- and 100-fold dilution).

Methods: FLC concentration was measured with Freelite® reagents on the BNII, using 100- and 2000-fold dilutions in 3645 samples.

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