2,490 results match your criteria: "University Hospital of Heraklion[Affiliation]"

Background/objective: Primary Focal and Segmental glomerulosclerosis (FSGS) is one of the most common causes of idiopathic nephrotic syndrome. Our aim was to describe a large cohort of patients with primary FSGS, identify risk factors associated with worse renal survival and assess the impact of different immunosuppressive regiments on renal survival.

Methods: This was a historical cohort study of adults who were diagnosed with primary FSGS from March 26, 1982, to September 16, 2020.

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Aerococcus urinae urinary tract infections: A case series.

Acta Microbiol Immunol Hung

December 2024

1Department of Clinical Microbiology and Microbial Pathogenesis, University Hospital of Heraklion, 71500 Crete, Greece.

Aerococcus urinae is an uncommon uropathogen that mainly affect the elderly with predisposing conditions. Aim of the present study was to investigate the clinical and microbiological characteristics of patients with urinary tract infections (UTIs) by A. urinae and determine the antimicrobial susceptibility patterns of the isolates, over the last 3 years at our institution.

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Artificial intelligence (AI) is transforming medical radiation applications by handling complex data, learning patterns, and making accurate predictions, leading to improved patient outcomes. This article examines the use of AI in optimizing radiation doses for X-ray imaging, improving radiotherapy outcomes, and briefly addresses the benefits, challenges, and limitations of AI integration into clinical workflows. In diagnostic radiology, AI plays a pivotal role in optimizing radiation exposure, reducing noise, enhancing image contrast, and lowering radiation doses, especially in high-dose procedures like computed tomography.

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Background: The screening strategy for interstitial lung disease (ILD) in rheumatoid arthritis patients is currently debated. While high-resolution computed tomography (HRCT) is the gold standard for diagnosing ILD, its systematic use as a screening tool is not yet recommended. The role of lung ultrasound (LUS) in assessing ILD has been previously explored.

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Objectives: To evaluate the combination of novel colour Doppler ultrasound (CDUS), greyscale ultrasound (GSUS), and oscillometric indices of macroangiopathy in patients with idiopathic inflammatory myopathies (IIM). Second, to explore the associations between these imaging markers and both patient-related and disease-related characteristics, as well as traditional cardiovascular (CV) risk factors.

Methods: We conducted CDUS to evaluate arterial compliance markers, specifically the resistance (RI) and pulsatility (PI) indices, both in the common (CCA) and internal carotid arteries (ICA) of patients with IIM and healthy controls.

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Background: Pseudomonas aeruginosa (PA) bloodstream infection (BSI) is a common healthcare-associated complication linked to antimicrobial resistance and high mortality. Ongoing clinical trials are exploring novel anti-virulence agents, yet studies on how bacterial virulence affects PA infection outcomes is conflicting and data from real-world clinical populations is limited.

Methods: We studied a multicentre cohort of 773 adult patients with PA BSI consecutively collected during 7-years from sites in Europe and Australia.

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Background: Pulmonary arterial hypertension (PAH) is a severe complication among adult patients with congenital heart disease (ACHD). This study presents real-world data on risk stratification, pharmacotherapy and survival rates in PAH-ACHD.

Methods: Data from PAH-ACHD patients were analyzed using The Hellenic Pulmonary Hypertension Registry (HOPE), spanning eight specialized centers between 2015 and 2023.

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Objectives: This study aims to estimate the vaccination rate against herpes zoster (HZ) among public Primary Health Care (PHC) visitors eligible for vaccination based on the National guidelines. It also aims to explore the determinants associated with vaccination utilizing the health beliefs model (HBM).

Materials And Methods: A cross-sectional study was conducted between October and December 2022.

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Background: The main purpose of this study was to determine the feasibility of sparing the rectoprostatic fascia (RPF) in adult male cadavers and in adult male patients who underwent total mesorectal excision (TME) for rectal cancer. A secondary objective was to evaluate urogenital function following rectal cancer surgery, pathologic, and oncologic outcomes.

Methods: In accordance with PRISMA guidelines, we performed a systematic review with an a priori design to identify relevant studies via MESH terms and keywords.

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Teaching transference focused psychotherapy to South African mental health practitioners.

S Afr J Psychiatr

November 2024

DeanCross Personality Disorder Service, East London NHS Foundation Trust, London, United Kingdom.

Background: Personality disorders (PDs) are estimated to occur in 6.8% of South Africans and in 45% to 80% of clinical populations. Mental health practitioners often harbour negative attitudes and lack confidence in working with such patients.

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Predictors of pregnancy outcomes in SLE.

Lancet Rheumatol

December 2024

Section of Molecular Pathology and Human Genetics, Department of Internal Medicine, School of Medicine, University of Crete, Heraklion 71003, Greece; Department of Internal Medicine, University Hospital of Heraklion, Heraklion, Greece. Electronic address:

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Article Synopsis
  • A study assessed the prevalence of post-traumatic stress syndrome (PTSS) among anaesthesiologists working in COVID-19 referral hospitals in Greece using the PTSD Checklist for DSM-5 (PCL-5) and the Eysenck Personality Questionnaire (EPQ).
  • Results showed that 18%-23% of participants exhibited PTSS, with 7% likely having PTSD; factors like having children and job satisfaction were protective against PTSS, while family obligations increased risk.
  • The study found that neuroticism and job ranking significantly predicted PTSS, with higher job levels correlating to an increased risk of developing the syndrome.
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Contemporary assessment of short- and functional 90-days outcome in old intensive care patients suffering from COVID-19.

J Crit Care

December 2024

Heinrich-Heine-University Duesseldorf, Medical Faculty, Department of Cardiology, Pulmonology and Vascular Medicine, Duesseldorf, Germany; Heinrich-Heine University, Medical Faculty, Department of Cardiology, Pulmonology and Vascular Medicine, Düsseldorf, Germany; CARID (Cardiovascular Research Institute Düsseldorf), Düsseldorf, Germany. Electronic address:

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Phlegmasia cerulea dolens (PCD) is a rare but limb-threatening complication of deep vein thrombosis. A 72-year-old hemodialysis male patient presented with upper limb PCD. The patient underwent hemodialysis via a permanent hemodialysis central venous catheter (HD-CVC) while a new brachial-cephalic AVF was created 1 month ago.

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Article Synopsis
  • Individuals with subjective cognitive decline (SCD) face a higher risk of developing dementia, and the GINGER initiative presents a multicomponent lifestyle intervention approach that includes exercise as a key component for prevention and management.
  • The exercise protocol designed for GINGER targets adults over 55 with SCD and involves a structured program of aerobic, strengthening, balance, and dual-task exercises, delivered three times a week, both in group sessions and at home.
  • The implementation of this exercise protocol was found to be feasible and reliable, showing good adherence and user satisfaction, along with notable improvements in physical health outcomes among participants.
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Purpose Of Review: To summarize basic physiological concepts of breathing effort and outline various methods for monitoring effort of inspiratory and expiratory muscles.

Recent Findings: Esophageal pressure (Pes) measurement is the reference standard for respiratory muscle effort quantification, but various noninvasive screening tools have been proposed. Expiratory occlusion pressures (P0.

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Article Synopsis
  • This study investigates the prevalence of vitamin B12 deficiency in hospitalized adults aged 65 and older, along with associated factors and its effects on health outcomes like frailty and functional decline.
  • Data were collected from 894 older patients, revealing a 9.1% prevalence of B12 deficiency, with low albumin levels, polypharmacy, and nursing home residency identified as key contributing factors.
  • The findings highlight that B12 deficiency correlates with increased frailty and reduced functional status, emphasizing the need for routine screenings to enhance the quality of care for older adults in hospitals.
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Aim: This study investigates the demographic distribution, antibiotic resistance profiles, and molecular characteristics of infections.

Methods: The study was carried out in 141 patients, 60.4% male, in patients from Chania and Heraklion, Crete.

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Background/objectives: Vaccination of pregnant and postpartum women for pertussis, influenza and COVID-19 not only protects themselves but also offspring. Despite the benefits of this approach, vaccination uptake remains suboptimal in pregnancy. Where the opportunity to be vaccinated in pregnancy is missed, the offer of vaccination in the post-partum period may be an alternative strategy.

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Radiomics is a method to extract detailed information from diagnostic images that cannot be perceived by the naked eye. Although radiomics research carries great potential to improve clinical decision-making, its inherent methodological complexities make it difficult to comprehend every step of the analysis, often causing reproducibility and generalizability issues that hinder clinical adoption. Critical steps in the radiomics analysis and model development pipeline-such as image, application of image filters, and selection of feature extraction parameters-can greatly affect the values of radiomic features.

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Background: Implementing asthma guideline recommendations is challenging and there is variation between countries, and different healthcare professionals (HCPs). The International Primary Care Respiratory Group (IPCRG) has introduced the Asthma Right Care (ARC) programme implemented in 24 low, middle, and high countries, including Greece. It offers a promising approach drawn from social movements for health to improve asthma care by engaging HCPs in implementing guideline-based asthma care.

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Post-Discharge Outcomes of Elderly Patients Hospitalized for Inflammatory Bowel Disease Flare Complicated by Clostridioides difficile Infection.

J Crohns Colitis

October 2024

Division of Gastroenterology, Rabin Medical Center, affiliated with the Faculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv, Israel.

Objectives: Elderly hospitalized patients with inflammatory bowel disease (IBD) flare and concurrent Clostridioides difficile infection (CDI) are considered at high risk of IBD-related complications. We aimed to evaluate the short, intermediate, and long-term post-discharge complications among these patients.

Methods: A retrospective multicenter cohort study assessing outcomes of elderly individuals (≥60 years) hospitalized for an IBD flare who were tested for CDI (either positive or negative) and discharged.

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