12 results match your criteria: "University Hospital of Galdakao Usansolo[Affiliation]"

ESVS Podcasts: Connecting with the World.

EJVES Vasc Forum

January 2023

Department of Vascular Surgery, Odense University Hospital, University of Southern Denmark, Odense, Denmark.

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Transscleral Cyclophotocoagulation for the Treatment of Uncontrolled Glaucoma in a Boston Keratoprosthesis Type II Patient.

Case Rep Ophthalmol

March 2022

Department of Ophthalmology, BioCruces Bizkaia Health Research Institute, University Hospital of Cruces, Begiker, Plaza de Cruces S/N, Barakaldo, Spain.

Postoperative endoscopic cyclophotocoagulation (CPC) for the treatment of glaucoma in patients with Boston keratoprosthesis type II (BKPro II) was first described in 2017 by Poon et al. (). As we do not have this device, we present a case of transscleral CPC (TSCPC), in a BKPro II patient who had graft versus host disease and developed uncontrolled glaucoma.

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Background: Interindividual genetic variations contribute to differences in patients' response to drugs as well as to the development of certain disorders. Patients who use non-steroidal anti-inflammatory drugs (NSAIDs) may develop serious gastrointestinal disorders, mainly upper gastrointestinal haemorrhage (UGIH). Studies about the interaction between NSAIDs and genetic variations on the risk of UGIH are scarce.

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Bleeding in non-steroidal anti-inflammatory drug (NSAID) users limited their prescription. This first multicenter full case-control study (325 cases and 744 controls), explored the association of e-NOS intron 4 variable number tandem repeat (VNTR) polymorphism with upper gastrointestinal hemorrhage (UGIH) in NSAID exposed and unexposed populations and assessed any interaction between this polymorphism and NSAIDs. NSAID users carrying e-NOS intron 4 wild type genotype or VNTR polymorphism have higher odds of UGIH than those unexposed to NSAIDs [Odds Ratio (OR): 6.

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Article Synopsis
  • The study investigates how specific genetic variations (SNPs) can influence the risk of upper gastrointestinal hemorrhage (UGIH) in patients taking low-dose aspirin, despite its known benefits.
  • A multicenter case-control approach was utilized, comparing 326 UGIH cases with 748 aspirin-exposed and unexposed controls, focusing on patients of European descent.
  • The findings identified seven SNPs that increased the risk of UGIH with aspirin use (positive modifiers) and nine SNPs that potentially reduced that risk, emphasizing the need for personalized medical approaches regarding aspirin prescriptions.
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Q Fever (Coxiella Burnetii).

Semin Respir Crit Care Med

August 2020

Department of Pneumology, Hospital Clinic of Barcelona, Barcelona, Spain.

Q fever is a zoonotic infectious disease caused by the bacterium. It is an obligate intracellular pathogen with a high infection capacity that proliferates exclusively in an acidified medium, forming a lysosome-like vacuole. It presents a peculiar phenomenon called "antigenic phase variation," produced by a modification in the complexity of the membrane lipopolysaccharides.

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