139 results match your criteria: "University Hospital of Foggia[Affiliation]"

Purpose: Gastrointestinal (GI) dysfunction is common in critically ill patients and associated with poor outcomes. There is a lack of standardised methods for daily monitoring of GI function. COSMOGI aimed to develop a Core Outcome Set (COS) for daily monitoring of GI function to improve consistency and comparability in future studies in critically ill patients.

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How to define parenteral nutrition.

Crit Care

November 2024

Department of Anaesthesiology and Intensive Care, Institute of Clinical Medicine, University of Tartu, Tartu, Estonia.

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Article Synopsis
  • Micronutrient (MN) alterations in critically ill patients can lead to complications, but improving MN status may help as a supportive therapy.
  • This review, done by a specialized group, focuses on individual important MNs, such as vitamins A, B, C, D, E, as well as minerals like iron and zinc, to guide future research.
  • It emphasizes that high-dose single MN treatments are not advised; instead, patients should receive daily basal needs, with adjustments for higher requirements and treatment for deficiencies, and lists ongoing trials and future research priorities.
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  • The study investigates foreign body ingestion (FBI) in children under 18 in Italy, highlighting the prevalence and trends from 2015 to 2020.
  • A total of 5,771 cases were analyzed, with the majority occurring at home, mostly involving children under 6, and commonly featuring blunt objects.
  • The results indicate stable rates of FBI over time, urging the importance of preventive strategies to protect young children, especially those 5 and under, from such incidents.
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A Non-Invasive Technique to Unveil Renal Implications in Anderson-Fabry Disease.

Biomedicines

August 2024

Nephrology, Dialysis and Transplantation Unit, Advanced Research Center on Kidney Aging (A.R.K.A.), Department of Medical and Surgical Sciences, University of Foggia, 71122 Foggia, Italy.

Article Synopsis
  • Anderson-Fabry disease (AFD) is a rare genetic disorder that leads to organ damage due to a lack of α-galactosidase A, causing harmful substances to accumulate in tissues, particularly affecting the heart and kidneys.
  • * Researchers conducted a study using cardiovascular magnetic resonance (CMR) and T1 mapping to evaluate kidney involvement in 19 AFD patients compared to a control group without kidney disease.
  • * The findings indicated a positive correlation between heart and kidney T1 values in AFD patients, and a negative correlation in kidney T1 values between AFD and control patients, suggesting kidney damage from microvascular issues in AFD.
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  • Multisystem Inflammatory Syndrome in Children (MIS-C) can occur 3-6 weeks after a SARS-CoV2 infection, and vaccinated adolescents show fewer severe cases, but data on younger kids is limited.
  • A 6-year-old girl developed MIS-C symptoms one month after receiving her COVID-19 vaccine, despite having no prior detectable infection; diagnosis was confirmed through antibody tests.
  • Treatment with immunoglobulins and steroids helped her recover, but she experienced additional complications like pancreatitis and neurological symptoms; follow-up showed no lasting issues, raising questions about the vaccine's role in MIS-C for younger children.
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Spasticity management should be provided within the context of a comprehensive person-centered rehabilitation program. Furthermore, active goal setting for specific spasticity interventions is also important, with a well-established "more is better" approach. It is critical to consider adjunctive therapy and multimodal approaches if patients are not attaining their treatment goals.

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In recent decades, there has been considerable effort in investigating the clinical utility of renal Doppler measurements in both cardiovascular and renal disorders. In particular, a measure of renal arterial resistance, the renal resistive index (RRI), has been demonstrated to predict chronic kidney disease progression and acute kidney injury in different clinical settings. Furthermore, it is linked to a poorer prognosis in individuals suffering from chronic heart failure.

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Only a few studies have investigated olfactory function in patients with obstructive sleep apnea syndrome (OSAS) using psychophysical testing, and there is a scarcity of data regarding taste evaluation in the existing literature. The primary objectives of this study were to assess both smell and taste in patients with OSAS and to explore the correlation between the severity of symptoms and sensory perception. A total of 85 OSAS patients and a control group comprising 81 subjects were enrolled.

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Validation of the Quality Analysis of Medical Artificial Intelligence (QAMAI) tool: a new tool to assess the quality of health information provided by AI platforms.

Eur Arch Otorhinolaryngol

November 2024

Maxillofacial Surgery Operative Unit, Department of Medicine, Surgery and Pharmacy, University of Sassari, Viale San Pietro 43/B, 07100, Sassari, Italy.

Article Synopsis
  • The study introduced the Quality Assessment of Medical Artificial Intelligence (QAMAI), a tool aimed at evaluating the quality of health information from AI platforms, highlighting the need for such assessments as AI use expands in healthcare.
  • QAMAI was validated through a rigorous process involving 27 reviewers who evaluated responses generated by ChatGPT4, demonstrating strong reliability and validity metrics, including a high internal consistency (Cronbach's alpha = 0.837) and excellent inter-rater reliability (ICC = 0.983).
  • The successful validation of QAMAI suggests it could be an important resource for healthcare professionals as more patients turn to AI for medical information, helping ensure they receive quality data.
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Introduction: Comparison of the marker kinetics procalcitonin, presepsin, and endotoxin during extracorporeal hemoperfusion with polymyxin-B adsorbing cartridge (PMX-HA) has never been described in abdominal sepsis. We aimed to compare the trend of three biomarkers in septic post-surgical abdominal patients in intensive care unit (ICU) treated with PMX-HA and their prognostic value.

Methods: Ninety abdominal post-surgical patients were enrolled into different groups according to the evidence of postoperative sepsis or not.

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Background: Biologic agents are considered a new revolutionized therapy for severe and recurrent forms of CRSwNP which disease burden is not sufficiently controlled by conservative and/or surgical treatments. Recent Research has focused on evaluating their real-life efficacy in CRSwNP, as only limited reports on real-life data are available. However, in most studies, the response to treatment is evaluated in terms of improvement in Nasal Polyp Score (NPS) or in Sino-Nasal Outcome test (SNOT-22) scores.

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Taste loss in COVID-19 â€" psychophysical evidence supporting a low prevalence.

Rhinology

August 2024

Smell and Taste Clinic, Department of Otorhinolaryngology, Technische Universitat Dresden, Dresden, Germany.

Much - possibly even too much - has been published about chemosensory dysfunction as a consequence of COVID-19. Studies have reported prevalence of taste loss in up to 89.9%, which is in a similar range as COVID-19 related smell loss.

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Article Synopsis
  • - The study focuses on RSV, a common virus causing severe respiratory infections in infants, particularly in those under two months old, and evaluates its impact on hospitalizations at Policlinico Foggia Hospital in Italy from 2011 to 2023.
  • - Data from 1,005 RSV cases reveals that most hospitalizations occur during winter months, with a significant majority of affected patients being under one year old, and highlights that factors such as younger age, longer hospital stays, and prematurity increase disease severity.
  • - The financial burden of RSV hospitalizations averages around 3,036 euros annually, with costs being notably higher for the youngest patients, indicating the potential benefits of new immunization strategies, including the use of monoclon
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Methodological challenges in systematic reviews of mHealth interventions: Survey and consensus-based recommendations.

Int J Med Inform

April 2024

Institute for Complementary and Integrative Medicine, University Hospital Zurich and University of Zurich, Zurich, Switzerland; Center for Integrative Medicine, University of Maryland School of Medicine, Baltimore, MD, United States; Institute for Social Medicine, Epidemiology and Health Economics, Charité - Universitätsmedizin Berlin, Berlin, Germany.

Objective: Mobile Health (mHealth) refers to using mobile devices to support health. This study aimed to identify specific methodological challenges in systematic reviews (SRs) of mHealth interventions and to develop guidance for addressing selected challenges.

Study Design And Setting: Two-phase participatory research project.

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Article Synopsis
  • Medical researchers are increasingly concerned about the impact of microplastics on human health, particularly in organs and tissues like the kidneys. !* -
  • A study utilized microRaman spectroscopy to analyze kidney and urine samples from healthy individuals, identifying 26 microplastic particles in both, ranging in size from 1 to 29 μm. !* -
  • The polymers found most often were polyethylene and polystyrene, while pigments included hematite and Cu-phthalocyanine, marking the first documented evidence of microplastics in human kidney tissues and urine. !*
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A strong correlation has been reported between patient-reported quality of life (QoL) and the investigator-rated Disability Assessment Scale (DAS) in patients with spasticity. The current analysis evaluates the effect of incobotulinumtoxinA on QoL-related outcomes (limb position abnormality, as well as dressing- and hygiene-related disability, measured with the DAS) in adults with upper limb spasticity, using pooled data from six studies. Separate analyses for each DAS domain were performed using data from patients with disabilities for that domain (DAS score ≥1).

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Left ventricular global longitudinal strain (GLS) has an important role in the diagnosis of cancer therapy-related cardiac dysfunction (CTRCD). Little is known about the role of atrial function in diagnosing CTRCD. The aim of our study was to assess the impact of anti-cancer drugs on atrial function measured by speckle-tracking echocardiography in breast cancer women.

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High-Definition 3D Exoscope in Pediatric Otorhinolaryngology: A Systematic Literature Review.

J Clin Med

October 2023

Research Group of Pediatric Otorhinolaryngology of the Task Force of the Young Otolaryngologists of the Italian Society of Otolaryngology-Head and Neck Surgery, Italy.

Unlabelled: This PRISMA-compliant systematic review aimed to investigate the use of and the most common procedures performed with the novel 3D 4K exoscope in surgical pediatric head and neck settings.

Methods: Search criteria were applied to PubMed, EMBASE and the Cochrane Review databases and included all studies published up to January 2023 reporting 3D 4K exoscope-assisted surgeries in pediatric patients. After the removal of duplicates, selection of abstracts and full-text articles, and quality assessment, we reviewed eligible articles for number of patients treated, age, surgical procedures, and outcomes.

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Chronic rhinosinusitis (CRS) is a complex and heterogeneous disorder whose etiopathogenetic picture is not yet completely known and is classically divided into CRS with (CRSwNP) and without nasal polyps (CRSsNP). But today the distinction is made with type 2 and nontype 2 variants. A rational and defined pathway for the diagnosis of chronic rhinosinusitis is an indispensable means to be able to arrive at a correct identification of the patient.

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Background: The sodium-glucose cotransporter-2 inhibitors (SGLT2i) have emerged as a crucial therapeutic option for patients with chronic heart failure with reduced ejection fraction (HFrEF). The aim of this study was to evaluate, in a real-world population from a single centre, the feasibility of introducing SGLT2i and their interaction with other recommended drug classes.

Methods: Consecutive patients affected by chronic heart failure (CHF) were evaluated beginning in January 2022.

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Introduction: To investigate the differences in the professional and personal life and the perception of gender-bias, among Italian female surgeons working in Otolaryngology-Head and Neck Surgery (OHNS), as compared to those involved in other surgical fields (overall group [OG]).

Materials And Methods: An online survey was administered to female medical doctors working in all surgical fields in Italian hospitals.

Results: Of the 1963 responders included, 153 (7.

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Oral microbiota in human health and disease: A perspective.

Exp Biol Med (Maywood)

August 2023

Department of Head, Neck and Sense Organs, Division of Oral Surgery and Implantology, Fondazione Policlinico Universitario A. Gemelli IRCCS, Università Cattolica del Sacro Cuore, Rome 00168, Italy.

Article Synopsis
  • - The article explores the significant role of oral microbiota in maintaining overall health, highlighting how various microbial species interact within the mouth and with the body.
  • - Factors like diet, poor oral hygiene, smoking, and certain medications can disrupt the balance of these microbes, leading to dysbiosis, which may cause oral issues like cavities and gum disease, as well as affect overall health.
  • - It discusses the importance of oral hygiene, diet, and probiotic supplementation as strategies to promote a healthy oral microbiome and prevent health complications.
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Foreign body ingestion in children: Definition of a nomogram to predict surgical or endoscopic intervention.

Dig Liver Dis

February 2024

Maternal and Child Health Department, Pediatric Gastroenterology and Liver Unit, Sapienza - University of Rome, Rome, Italy. Electronic address:

Background And Aims: Foreign body ingestion (FBI) in children requires early identification to prevent adverse outcomes and may necessitate endoscopic or surgical intervention. This study aims to develop a nomogram that identifies children who require urgent surgical or endoscopic intervention by using the patient's medical history and clinical parameters collected at admission.

Methods: This study is a retrospective review (01/2015-12/2020) of a multicenter case series of children admitted for FBI.

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Impact of the COVID-19 pandemic on paediatric otolaryngology: a nationwide study.

Acta Otorhinolaryngol Ital

October 2023

Research group of Pediatric Otorhinolaryngology of the Task Force of the Young Otolaryngologists of the Italian Society of Otolaryngology-Head and Neck Surgery.

Objective: The COVID-19 pandemic profoundly modified the work routine in healthcare; however, its impact on the field of paediatric otorhinolaryngology (ORL) has been rarely investigated. The aim of this study was to assess the impact of COVID-19 on paediatric ORL.

Methods: A questionnaire was developed by the Young Otolaryngologists of the Italian Society of ORL-Head and Neck Surgery (GOS).

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