1 results match your criteria: "University Hospital of Erlangen Germany.[Affiliation]"
Osteo-radio-necrosis (ORN) and bisphosphonate-related osteonecrosis of the jaws (BRONJ): the histopathological differences under the clinical similarities.
Int J Clin Exp Pathol
October 2014
Department of Oral and Maxillofacial Surgery, University Hospital of Erlangen Germany.
Article Synopsis
- The study aimed to differentiate histopathological features of osteoradionecrosis (ORN) and bisphosphonate-related osteonecrosis of the jaws (BRONJ), both clinically resembling exposed necrotic bone.
- ten samples of ORN, BRONJ, and normal mandibular bone were analyzed using bone-specific stains to assess collagen and osteon density differences.
- Results showed significant differences in collagen patterns and lower osteon density in BRONJ samples, indicating distinct underlying pathophysiological mechanisms for each condition.