4 results match your criteria: "University Hospital of Brussels (HUB)[Affiliation]"
Angiotensin-(1-7) infusion in COVID-19 patients admitted to the ICU: a seamless phase 1-2 randomized clinical trial.
Ann Intensive Care
September 2024
National Institute of Science and Technology in Nanobiopharmaceutics (INCT-Nanobiofar), Laboratory of Hypertension, Institute of Biological Sciences, Department of Physiology and Biophysics, Federal University of Minas Gerais, Belo Horizonte, Minas Gerais Av. Antonio Carlos, 6627-ICB-UFMG, Belo Horizonte, 31270-901, Brazil.
Background: The coronavirus-related disease (COVID-19) is mainly characterized by a respiratory involvement. The renin-angiotensin system (RAS) has a relevant role in the pathogenesis of COVID-19, as the virus enters host's cells via the angiotensin-converting enzyme 2 (ACE2).
Methods: This investigator-initiated, seamless phase 1-2 randomized clinical trial was conceived to test the safety and efficacy of continuous short-term (up to 7 days) intravenous administration of Angiotensin-(1-7) in COVID-19 patients admitted to two intensive care units (ICU).
Ketone Bodies after Cardiac Arrest: A Narrative Review and the Rationale for Use.
Cells
May 2024
Department of Intensive Care, University Hospital of Brussels (HUB), 1070 Brussels, Belgium.
Cardiac arrest survivors suffer the repercussions of anoxic brain injury, a critical factor influencing long-term prognosis. This injury is characterised by profound and enduring metabolic impairment. Ketone bodies, an alternative energetic resource in physiological states such as exercise, fasting, and extended starvation, are avidly taken up and used by the brain.
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- Macrocephaly is when head size is significantly larger than average for a child's age and sex, and the case presented involves a 16-month-old boy who had congenital progressive macrocephaly and required a shunt for hydrocephalus.
- After initially experiencing complications following the shunt placement, including seizures and anomalies in brain wave patterns, further examination revealed abnormal brain blood vessels indicative of a dural arteriovenous fistula (DAVF).
- The DAVF, which is a rare but significant cause of macrocephaly, was treated successfully with interventional procedures, highlighting the importance of carefully monitoring head size in diagnosing related conditions.
Endoscopic Management of Difficult Biliary Stones: An Evergreen Issue.
Medicina (Kaunas)
February 2024
Department of Gastroenterology, "Konstantopoulio-Patision" General Hospital of Nea Ionia, 14233 Athens, Greece.
Choledocholithiasis is one of the most common indications for endoscopic retrograde cholangiopancreatography (ERCP) in daily practice. Although the majority of stones are small and can be easily removed in a single endoscopy session, approximately 10-15% of patients have complex biliary stones, requiring additional procedures for an optimum clinical outcome. A plethora of endoscopic methods is available for the removal of difficult biliary stones, including papillary large balloon dilation, mechanical lithotripsy, and electrohydraulic and laser lithotripsy.
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