1 results match your criteria: "University Hospital Southampton NHS Foundation Trust. h.houlden@ucl.ac.uk.[Affiliation]"
Genetic Variants Are an Underlying Cause of Familial Intracranial Aneurysms.
Neurology
February 2021
From the Stroke Research Centre (I.C.H., V.A., M.M.B., D.J.W.), MRC Centre for Neuromuscular Diseases (B.O., E.B.), and Department of Neuromuscular Disorders (E.B., J.V.), UCL Queen Square Institute of Neurology; Neurogenetics Laboratory (I.C.H., B.O., E.O., H.H.) and Departments of Neuroradiology (I.D.) and Neurosurgery (N.K., J.G.), the National Hospital for Neurology and Neurosurgery, University College London Hospitals NHS Foundation Trust, Queen Square, London; Department of Anaesthesia (S.B.), the James Cook University Hospital, Middlesbrough; Department of Neurosurgery (D.W.), King's College Hospital NHS Foundation Trust, London; and Department of Neurosurgery (D.B.), University Hospital Southampton NHS Foundation Trust.
Purpose: To understand the role of the angiopoietin-like 6 gene () in intracranial aneurysms (IAs), we investigated its role in a large cohort of familial IAs.
Methods: Individuals with family history of IA were recruited to the Genetic and Observational Subarachnoid Haemorrhage (GOSH) study. The gene was sequenced using Sanger sequencing.