Primary testicular lymphoma: a strictly homogeneous hematological disease?

Primary testicular lymphomas display mostly aggressive diffuse large cell B-cell lymphomas, which could be further subclassified into germinal center B-cell-like and an activated B-cell phenotype via immunohistochemistry. A retrospective analysis of primary testicular lymphomas diagnosed at the Institute of Pathology, Salzburger Landeskliniken (SALK) between January 1997 and December 2008 was done. Immunohistochemical staining and complete clinical data evaluation was carried out and linked to overall survival time.

Aspects of the differential diagnosis of clear-cell lesions of the skin in connection with the rare case of a clear-cell atypical fibroxanthoma.

Clear-cell changes are rare in histological specimens of the dermis and raise complex diagnostic considerations regarding lineage differentiation (e.g., epithelial, mesenchymal, or melanocytic).