89 results match your criteria: "University Hospital Queen Giovanna - ISUL[Affiliation]"

The testicular artery is the vessel that provides oxygen-rich blood to the testes. It is also involved in many more processes that play important roles in spermatogenesis such as thermoregulation. As the vessel has a number of anatomical variants, it may be often responsible for difficulties and complications during abdominopelvic surgical procedures.

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BACKGROUND Malignant hyperthermia (MH) and anesthesia-induced rhabdomyolysis (AIR) are rare, yet life-threatening complications that need prompt therapeutic actions and logistic preparedness for treatment success. Both conditions are triggered by general anesthetics, particularly volatiles and depolarizing muscle relaxants. In comparison with MH, which is an inherited pharmacogenomic disease of calcium channel receptor subpopulation and arises only after trigger exposure, AIR has been described mostly in patients with muscular dystrophies.

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Purpose: The current meta-analysis aimed to investigate the extensor digitorum brevis manus (EDBM) muscle variability by calculating the pooled prevalence of all published variants. After considering the pooled prevalence, these variants were classified based on their insertion and relationship with the extensor indicis (EI) muscle and/or tendon. The origin of the variants, neural and arterial supply, and the terminology of the EDBM variants were further investigated.

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Periprosthetic joint infection (PJI) is a rare yet serious complication following a total hip replacement, predominantly caused by gram-positive bacteria such as and However, gram-negative pathogens can also be isolated. This case report presents a 22-year-old patient with a PJI caused by after total hip replacement due to a motor vehicle accident. The patient with a clinical history of total hip replacement secondary to posttraumatic arthrosis presented to our department with clinical and laboratory indications of PJI in the right hip.

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Lung cancer is commonly diagnosed at advanced stages, often presenting with metastases. Although bone metastases are common in lung cancer patients, acrometastases - metastatic lesions in the bones of the hand - are exceedingly rare. Herein, we report the case of a 71-year-old male with previously undiagnosed lung adenocarcinoma, which first manifested as a painful swelling in the right hand.

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Article Synopsis
  • Hemangiomas are benign tumors caused by abnormal blood vessel growth, which can be difficult to identify and treat, especially in uncommon locations like the foot.
  • A case study of a 36-year-old woman with a plantar hemangioma involved MRI detection and surgical removal, which was complicated by a rupture during the procedure but ultimately successful.
  • The case underscores the importance of accurate diagnosis through physical exams and imaging to differentiate benign tumors from malignant ones, as well as the need for tailored treatment options depending on the circumstances.
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  • Schwannomas are benign tumors from Schwann cells, commonly appearing in the head, neck, and upper limbs, but rare in the lower limbs; they can be sporadic or linked to genetic issues like neurofibromatosis type 2.
  • The case discussed involves a 57-year-old woman with a painless mass in her leg, diagnosed through physical examination and imaging as a benign nerve sheath tumor, later confirmed as schwannoma after surgery.
  • The recovery was smooth, with no complications in follow-up, underscoring the need for careful examination and imaging in diagnosing schwannomas, especially for lower limb masses.
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Article Synopsis
  • The forearm extensor muscle and hand extensor tendons show significant anatomical variability, highlighted during a dissection of a 74-year-old male cadaver.
  • An accessory muscle known as the extensor digitorum brevis manus (EDBM) was discovered, which connected to the extensor indicis (EI) tendon, indicating a rare anatomical variant.
  • This variant has a prevalence rate of 0.36-0.38% in cadaver studies, and understanding such variations is crucial for orthopedic and plastic surgeons to prevent accidental injuries during procedures.
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Profiles of primary brain abscesses and their impact on survival: An international ID-IRI study.

Int J Infect Dis

October 2024

Gulhane School of Medicine, Department of Infectious Diseases and Clinical Microbiology, University of Health Sciences, Ankara, Türkiye.

Article Synopsis
  • This study analyzed 331 patients with primary brain abscesses (PBAs) from 39 centers in 16 countries, focusing on infection causes, risk factors, and mortality outcomes over a 12-year period.
  • Study results showed that the majority of patients were middle-aged men (average age 46.8), with symptoms like headaches and fever; Gram-positive cocci were the most common pathogens.
  • Key factors influencing mortality at 42 days included intravenous drug use and malignancy, while factors affecting 180-day mortality included temporal lobe involvement and the presence of unidentified bacteria.
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Angiogenesis, the natural mechanism by which fresh blood vessels develop from preexisting ones, is altered in arterial hypertension (AH), impacting renal function. Studies have shown that hypertension-induced renal damage involves changes in capillary density (CD), indicating alterations in vascularization. We aimed to elucidate the role of the apelin receptor (APLNR), neuronal nitric oxide synthase (nNOS), and vascular endothelial growth factor (VEGF) in hypertension-induced renal damage.

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Multiple scapula defects or foramina or both?

Morphologie

December 2024

Department of Anatomy, School of Medicine, National and Kapodistrian University of Athens, 75, Mikras Asias str., Goudi, 11527 Athens, Greece. Electronic address:

The current bone report describes multiple openings identified in a dried scapula of a subject of unknown age and gender. Multiple openings (twelve) were identified in the subscapular fossa and were apparent at the infraspinatus fossa. These openings coexisted with a suprascapular foramen and an osteophyte at the inferomedial border of the foramen.

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The superior thyroid artery origin pattern: a systematic review with meta-analysis.

Surg Radiol Anat

September 2024

Department of Anatomy, School of Medicine, Faculty of Health Sciences, National and Kapodistrian University of Athens, 75 Mikras Asias str, Goudi, Athens, 11527, Greece.

Purpose: The current systematic review with meta-analysis aimed to investigate the pooled prevalence of the superior thyroid artery (STA) pattern of origin (distinct or fused-common origin with adjacent arteries in the form of a common trunk). The standard and uncommon variants were also studied, considering the STA's exact surface of origin and the relationship with the upper border of the thyroid cartilage (TC, reference point), considering the laterality effect. Thus, the STA topographical anatomy was considered.

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Purpose: A deep knowledge of the variations of the posterior forearm musculature is crucial for assessing and diagnosing conditions in this region. Extensor indicis (EI) is one of the muscles in this region, which exhibits diverse anatomical variations. This report documents an extremely unusual form of the EI with an accessory head on the dorsum of the hand.

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Please be very careful, when describing variant muscle.

Folia Morphol (Warsz)

June 2024

Department of Orthopedics and Traumatology, University Hospital Queen Giovanna - ISUL, Medical University of Sofia, Bulgaria.

This is Letter accompanies a Case Report, see article.

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A Rare Case of Large Lateral Chest Wall Hibernoma.

Cureus

May 2024

Department of Orthopedics and Traumatology, University Hospital Queen Giovanna-ISUL, Medical University of Sofia, Sofia, BGR.

Hibernomas, rare benign tumors originating from brown adipose tissue, pose diagnostic challenges due to their infrequent occurrence and slow growth. We present a case of a 38-year-old woman with a progressively enlarging mass in her right lateral chest wall, initially stable in size but growing during pregnancy and causing pain and functional impairment. Radiological evaluation, including x-ray and MRI, provided inconclusive results, necessitating a biopsy for a definitive diagnosis.

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Background: Sartorius muscle (SM) belongs to the thigh anterior compartment musculature. It corresponds to the longest muscle of the human body, while its variations are described rarely. The current case reports aims to describe a distal bifurcation of the SM, forming the bicaudatus SM variant.

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The human knee is a complex joint that comprises several ligaments, including the medial collateral ligament (MCL). The MCL provides stability to the knee and helps prevent its excessive inward movement. The MCL also has a thin layer of connective tissue known as the epiligament (EL), which adheres to the ligament.

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What is the axillary arch (of Langer)?

J Anat

July 2024

Department of Anatomical Sciences, St. George's University, True Blue, Grenada.

Article Synopsis
  • - Weninger et al. (2023) conducted a large-scale study using 400 axillae from 200 unembalmed cadavers, identifying the axillary arch (AA) in 27 axillae and describing its composition as either muscular, connective tissue, or a combination of both.
  • - The study found that in 63% of cases, after moving the arm, the AA contacted the neurovascular axillary bundle, highlighting its clinical significance.
  • - The authors commend the research for its detailed illustrations and contribution to medical literature, while also questioning the definition and historical context of the axillary arch as described by Langer in 1846.
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Purpose: Anterior compartment muscles of the arm present high morphological variability, with possible clinical significance. The current cadaveric report aims to describe a bilateral four-headed brachialis muscle (BM) with aberrant innervation. Emphasis on the embryological background and possible clinical significance are also provided.

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The enigmatic os supratrochleare anterius: from rarity to recognition in elbow pathology-case report and review of literature.

Surg Radiol Anat

April 2024

Department of Orthopedics and Traumatology, University Hospital Queen Giovanna-ISUL, Medical University of Sofia, 8, Bialo More Str., 1527, Sofia, Bulgaria.

Accessory bones around the elbow are scarce, with a reported mean incidence rate of 0.77%. The rarest one is the os supratrochleare anterius, with only a handful of documented cases in the literature.

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Background: During the COVID pandemic, research has shown an increase in candidemia cases following severe COVID infection and the identification of risk factors associated with candidemia. However, there is a lack of studies that specifically explore clinical outcomes and mortality rates related to candidemia after COVID infection.

Objectives: The aim of this international study was to evaluate the clinical outcomes and identify factors influencing mortality in patients who developed candidemia during their COVID infection.

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The fibularis brevis muscle belongs to the lateral compartment of the leg. It originates from the lower two-thirds of the lateral surface of the fibula bone and it also is attached to the anterior intermuscular septum. Its insertion is normally located on the tuberosity at the base of the fifth metatarsal bone, on its lateral side.

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