5 results match your criteria: "University Hospital Paris Saclay[Affiliation]"

Long-term follow-up MR imaging in children with transverse myelitis.

Mult Scler Relat Disord

December 2024

Department of Pediatric Neurology, Children´s Hospital Datteln, University Witten/Herdecke, Dr. Friedrich-Steiner Str. 5, Datteln D-45711, Germany.

Article Synopsis
  • The study investigates how lesions in children with transverse myelitis (TM) resolve over time, focusing on different related diseases: MOG-antibody associated disorders (MOGAD), multiple sclerosis (MS), neuromyelitis optica spectrum disorders (NMOSD), and double seronegative TM.
  • A total of 78 children from various medical centers were assessed, and a grading system was used to measure the resolution of lesions over time.
  • Results showed that MOGAD had the fastest and most complete resolution of lesions, followed by double seronegative TM, MS, and NMOSD, with none of the NMOSD patients achieving complete resolution during the observation period.
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The kappa free light chains index is an accurate diagnostic biomarker for paediatric multiple sclerosis.

Mult Scler

October 2024

Clinical Immunology Laboratory, Groupe Hospitalier Universitaire Paris Saclay, Hôpital Bicêtre, Assistance Publique-Hôpitaux de Paris, Le Kremlin-Bicêtre, France.

Background: Multiple sclerosis (MS) may occur before the age of 18. Differentiation between paediatric MS (PedMS) and other demyelinating syndromes (ODSs) is challenging. In adult with MS, the kappa free light chain (KFLC) index has proven to be a reliable marker of intrathecal Ig synthesis.

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Optimisation of pharmacotherapy in psychiatry through therapeutic drug monitoring, molecular brain imaging and pharmacogenetic tests: Focus on antipsychotics.

World J Biol Psychiatry

November 2024

Department of Psychiatry, Unit of Pharmacogenetics and Clinical Psychopharmacology, Center for Psychiatric Neuroscience, Lausanne University Hospital, Prilly, Switzerland.

Background: For psychotic disorders (i.e. schizophrenia), pharmacotherapy plays a key role in controlling acute and long-term symptoms.

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Perception of Paternal Postpartum Depression among Healthcare Professionals: A Qualitative Study.

Healthcare (Basel)

December 2023

Department of Psychiatry, Bicêtre University Hospital, Assistance Publique Hôpitaux de Paris APHP, University Hospital Paris Saclay, 94275 Le Kremlin Bicêtre, France.

The pathway to parenthood constitutes a fundamental and transformative stage in every individual's life. While postpartum depression in mothers has been increasingly studied and acknowledged, paternal postpartum depression (PPD) has garnered only moderate research attention. This study aims to delve into the comprehension and knowledge of healthcare professionals who may encounter men suffering from postpartum depression.

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Background: Previous studies have reported that polymicrobial peritonitis in peritoneal dialysis (PD) is associated with poor outcomes, but recent data from European cohorts are scarce.

Methods: We included from the French Language Peritoneal Dialysis Registry all patients ≥18 years of age who started PD between January 2014 and November 2020. We compared microbiology and patient characteristics associated with mono- and polymicrobial peritonitis.

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