622 results match your criteria: "University Hospital Lewisham[Affiliation]"

Organophosphate (OP) compounds, developed during World War II, are a group of chemicals used as pesticides, insecticides and herbicides. As irreversible inhibitors of the enzyme acetylcholinesterase (AChE), they reduce anti-cholinesterase activity and therefore increase acetylcholine (ACh) levels at the neuromuscular junction (NMJ). Diazinon, the OP leading to the patient's symptoms in this report, is an amber-brown liquid that was once the most widely used insecticide in the United States of America.

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Effect of Facial Fillers on Post-rhinoplasty edema: A Hypothesis Based on Literature Review.

Facial Plast Surg

December 2024

Division of ENT/Head and Neck/Facial Plastic and Reconstructive Surgery, Department of Aesthetic Facial Surgery, Institute of Medical Sciences, Canterbury Christ Church University, Kent, United Kingdom.

The quest to achieve younger and media-driven facial aesthetics has resulted in an exponential increase in the use of facial fillers. Inevitably, this has meant that it is now commonplace for facial plastic surgeons to have patients with fillers in the face. In the senior author's experience (A.

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Background: Adult humeral shaft fractures have traditionally been managed conservatively, but surgical intervention is considered for displaced fractures or when conservative treatment is unlikely to be successful. The optimal surgical approach remains controversial, with open reduction and internal fixation (ORIF) using plates and screws considered the gold standard. However, concerns about soft tissue damage have led to the development of less invasive techniques, such as anterior bridge plating using minimally invasive plate osteosynthesis (MIPO).

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Introduction: Patient safety is the most important priority in the healthcare system. Medical universities always attempt to find innovative and more effective educational methods to improve the students' abilities for clinical decision-making and quality and safe care. Thus, this study was designed to evaluate the effect of scenario-based learning on the knowledge, attitude, and perception of nursing students about patient safety.

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Early surgical intervention is critical for strangulated Richter's hernia.

J Surg Case Rep

October 2024

Department of General Surgery, Lewisham and Greenwich NHS Trust, University Hospital Lewisham, Lewisham High St., London SE13 6LH, United Kingdom.

Richter's hernia is a rare but serious surgical emergency involving the entrapment or strangulation of part of the bowel's circumference in the hernial orifice, often without causing complete luminal obstruction. This case report describes a man in his 70s presenting with a 3-day history of abdominal pain and vomiting, despite normal bowel movements. Blood results revealed raised inflammatory markers, and computed tomography imaging suggested small bowel obstruction due to an incarcerated left inguinal hernia.

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Background: The International Academy of Cytology (IAC) has developed a standardized approach for reporting the findings of breast fine-needle aspiration cytology (FNAC). Accordingly, there are five chief categories of breast lesions, C1 (insufficient material), C2 (benign), C3 (atypical), C4 (suspicious), and C5 (malignant). The prognostication and management of breast carcinoma can be performed readily on the basis of this classification system.

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Skull Base Chordoma and Chondrosarcoma: Neuroradiologist's Guide to Diagnosis, Surgical Management, and Proton Beam Therapy.

Radiographics

October 2024

From the Department of Radiology (G.M.P., P.B., M.W.) and ENT Surgery (R.K.B.), Manchester Royal Infirmary, Oxford Road, Manchester, United Kingdom M13 9WL; Department of Neuroradiology, Walton Centre NHS Foundation Trust, Liverpool, United Kingdom (R.S.); Department of Radiology, Salford Royal Hospital, Salford, United Kingdom (A.H., S.A.); Department of Neurosurgery, Salford Royal Hospital, Salford, United Kingdom (S.A.R., O.N.P.); University Hospital Lewisham, London, United Kingdom (O.I.); Department of Neurosurgery, Queen's Medical Centre, Nottinghamshire, United Kingdom and University of Nottingham, Nottingham, United Kingdom (L.J.G.); Department of Neurosurgery, Royal Sussex County Hospital Brighton, United Kingdom (C.L.H-W.); Division of Neuroscience (F.R.) and Division of Cancer Sciences (G.A.W.), University of Manchester, Manchester, United Kingdom; and Department of Clinical Oncology, Christie Hospital, Manchester, United Kingdom (R.J.C., S.P., G.A.W.).

Skull base chordomas and chondrosarcomas are distinct types of rare, locally aggressive mesenchymal tumors that share key principles of imaging investigation and multidisciplinary care. Maximal safe surgical resection is the treatment choice for each, often via an expanded endoscopic endonasal approach, with or without multilayer skull base repair. Postoperative adjuvant radiation therapy is frequently administered, usually with particle therapy such as proton beam therapy (PBT).

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Emergency care of metabolic bariatric surgery patients.

Br J Surg

August 2024

Multinational Advisory Group for International Federation for the Surgery of Obesity and Metabolic Disorders European Chapter, Naples, Italy.

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Article Synopsis
  • Posterolateral impingement can cause persistent elbow pain, often misdiagnosed after treatments for other conditions like tennis elbow or related issues in athletes.
  • Effective arthroscopic surgery targets abnormal structures, but caution is needed during olecranon excision to avoid instability.
  • A systematic review highlights anatomical variations and overloading as factors contributing to this condition, suggesting a need for improved understanding to develop better treatment and prevention strategies.
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Multiple myeloma (MM) typically presents with characteristic symptoms such as bone pain, hypercalcaemia, renal dysfunction, and anaemia. However, atypical presentations of MM, though rare, have been reported. These atypical presentations pose a diagnostic challenge due to their varied clinical manifestations, leading to potential delays in diagnosis and treatment initiation.

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Objectives: As a large language model (LLM) trained on a large data set, ChatGPT can perform a wide array of tasks without additional training. We evaluated the performance of ChatGPT on postgraduate UK medical examinations through a systematic literature review of ChatGPT's performance in UK postgraduate medical assessments and its performance on Member of Royal College of Physicians (MRCP) Part 1 examination.

Methods: Medline, Embase and Cochrane databases were searched.

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Objectives: Anti-synthetase syndrome (ASS) is a chronic autoimmune condition, with interstitial lung disease (ILD) being a key feature. This systematic literature review (SLR; CRD42023416414) aimed to summarize treatments and outcomes of ILD associated with ASS (ASS-ILD).

Methods: Databases were searched for articles discussing ASS-ILD management and outcomes, published 1946-September 2023.

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Background: Robotic assisted surgery (RAS) has seen significant advancement in many surgical specialties, although the application of robotics in plastic and reconstructive surgery remains to be widely established. This systematic review aims to assess the role of RAS in plastic and reconstructive surgery.

Methods: The review protocol was published and registered a priori as CRD42024507420.

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Introduction: Approximately 20 % of femoral fragility fracture patients take anticoagulants, typically warfarin or Direct Oral AntiCoagulant (DOAC). These can impact timing of surgery affecting patient survival. Due to several possible approaches and numerous factors to consider in the preoperative workup of anticoagulated patients, potential for variations in clinical practice exist.

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Purpose: The detection of congenital heart disease (CHD) before neonatal surgery is crucial for anaesthetic and perioperative management. There are no established criteria for pre-operative echocardiography in neonates. We aimed to survey current practice in the United Kingdom and evaluate the reliability of antenatal screening and postnatal clinical assessment in detecting CHD before surgery.

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Background During the COVID-19 pandemic, there was a need to balance optimum treatment service and the safety of patients and hospital staff. The British Orthopaedic Association recommended a virtual fracture clinic to give the right first-time decision and to minimize patient exposure to disease. This study aimed to evaluate the patients' satisfaction outcomes for the service provided through the virtual fracture clinic.

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Point-of-care gastric ultrasound: believing is seeing.

Can J Anaesth

August 2024

Department of Anaesthesia, Guy's and St Thomas' NHS Foundation Trust, London, UK.

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Background: Management of benign vocal fold lesions (BVFLs) is variable with individuals receiving surgery, voice therapy, or a combination of these approaches. Some evidence suggests that the best outcomes may be achieved when patients are offered pre- and post-operative voice therapy in addition to phonosurgery, but what constitutes pre- and post-operative voice therapy is poorly described. The pre- and post-operative voice therapy (PAPOV) intervention has been developed and described according to the TIDieR checklist and Rehabilitation Treatment Specification System (RTSS) for voice.

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Immunoglobulin G4-related disease (IgG4-RD) is a multisystem fibroinflammatory condition. A consistent feature of many cases is pulmonary infiltrates, or respiratory failure. This systematic literature review aims to summarise the pulmonary manifestations of IgG4-RD, including clinical outcomes and treatment.

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