2 results match your criteria: "University Hospital Groningen and Groningen University Institute of Drug Exploration[Affiliation]"
Comparison of amino acid oxidation and urea metabolism in haemodialysis patients during fasting and meal intake.
Nephrol Dial Transplant
June 2004
Department of Internal Medicine, Division of Nephrology, University Hospital Groningen and Groningen University Institute of Drug Exploration, The Netherlands.
Background: The PNA (protein equivalent of nitrogen appearance) is used to calculate protein intake from urea kinetics. One of the essential assumptions in the calculation of PNA is that urea accumulation in haemodialysis (HD) patients is equivalent to amino acid oxidation. However, urea is hydrolysed in the intestine and the resulting ammonia could be used metabolically.
View Article and Find Full Text PDFProtein intake during hemodialysis maintains a positive whole body protein balance in chronic hemodialysis patients.
Am J Physiol Endocrinol Metab
May 2003
Division of Nephrology, Department of Internal Medicine, University Hospital Groningen and Groningen University Institute of Drug Exploration, Hanzeplein 1, 9713 GZ Groningen, The Netherlands.
Protein energy malnutrition is present in 18 to 56% of hemodialysis patients. Because hemodialysis has been regarded as a catabolic event, we studied whether consumption of a protein- and energy-enriched meal improves the whole body protein balance during dialysis in chronic hemodialysis (CHD) patients. Patients were studied on a single day between dialysis (HD- protocol) in the morning while fasting and in the afternoon while consuming six small test meals.
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