3 results match your criteria: "University Hospital FreiburgFreiburg[Affiliation]"
Balance Training Enhances Vestibular Function and Reduces Overactive Proprioceptive Feedback in Elderly.
Front Aging Neurosci
August 2017
Department of Neurology and Neurophysiology, University Hospital FreiburgFreiburg, Germany.
Postural control in elderly people is impaired by degradations of sensory, motor, and higher-level adaptive mechanisms. Here, we characterize the effects of a progressive balance training program on these postural control impairments using a brain network model based on system identification techniques. We analyzed postural control of 35 healthy elderly subjects and compared findings to data from 35 healthy young volunteers.
View Article and Find Full Text PDFHippocampal and Amygdala Gray Matter Loss in Elderly Controls with Subtle Cognitive Decline.
Front Aging Neurosci
March 2017
Affidea Carouge Radiologic Diagnostic Center, GenevaSwitzerland; Department of Surgical Sciences, Radiology, Uppsala University, UppsalaSweden; Department of Neuroradiology, University Hospital FreiburgFreiburg, Germany; Department of Neuroradiology, Faculty of Medicine of the University of GenevaGeneva, Switzerland.
In contrast to the idea that hippocampal and amygdala volume loss occur in late phases of neurodegeneration, recent contributions point to the relevance of preexisting structural deficits that are associated with aging and are independent of amyloid deposition in preclinical Alzheimer disease cases. The present work explores GM hippocampal and amygdala volumes in elderly controls displaying the first signs of cognitive decline. 455 subjects (263 females), including 374 controls (228 females) and 81 middle cognitive impairment subjects (35 females), underwent two neuropsychological evaluations (baseline and 18 months follow-up) and a MRI-T1 examination (only baseline).
View Article and Find Full Text PDFA Delphic consensus assessment: imaging and biomarkers in gastroenteropancreatic neuroendocrine tumor disease management.
Endocr Connect
September 2016
Yale UniversityNew Haven, Connecticut, USA
Article Synopsis
- The management of neuroendocrine neoplasia (NEN) is complicated by the limitations of current imaging methods and a lack of effective biomarkers, making disease assessment challenging.
- A Delphi consensus meeting of 33 NEN experts highlighted that while morphological imaging is valuable, existing imaging techniques and biomarkers are inadequate for accurately measuring disease status and predicting treatment responses.
- The panel emphasized the need for improved tools and proposed that combining advanced imaging with circulating multianalyte mRNA tests (like NETest) could enhance real-time monitoring of NEN progression and therapeutic outcomes.