9 results match your criteria: "University Hospital City of Health and Science of Turin[Affiliation]"

Article Synopsis
  • Interferon-based therapies like ropeginterferon alfa-2b are showing promise as potential treatments for essential thrombocythemia (ET), which current therapies don't modify or improve disease progression.
  • Ropeginterferon alfa-2b has been effective in treating polycythemia vera (PV) and could similarly benefit ET patients who can't tolerate or are resistant to existing treatments.
  • The ongoing ROP-ET trial aims to evaluate its effectiveness over three years, focusing on patient responses, quality of life, and safety, providing crucial data for treatment options in this underserved group.
View Article and Find Full Text PDF
Article Synopsis
  • The study investigates bloodstream infections caused by uncommon Enterobacterales species over five years, revealing a low prevalence of 0.4% among Gram-negative isolates.
  • In adults, malignancy is a common comorbidity, while in pediatric cases, cerebrovascular disease linked to meconium aspiration is notable; primary infections in adults are often bloodstream-related whereas in children, catheter and respiratory tract sources are more frequent.
  • Antibiotic susceptibility varies, with high effectiveness against most drugs except for a few, and targeted treatments included monotherapy for adults and combination therapy for pediatric cases, resulting in a low overall mortality rate of 5.3%.
View Article and Find Full Text PDF

Objectives: The aim of this study was to compare the efficacy of chemical and mechanical methods for decontamination of titanium dental implant surfaces previously infected with polymicrobial biofilms in a model simulating a peri-implant defect. Furthermore, the effect of each decontamination protocol on MG-63 osteoblast-like cells morphology and adhesion to the treated implants was assessed.

Background: Peri-implantitis is a growing issue in dentistry, and evidence about implant surface decontamination procedures is lacking and inconclusive.

View Article and Find Full Text PDF

Determinants of SARS-CoV-2 infection in Italian healthcare workers: a multicenter study.

Sci Rep

March 2021

Department of Biomedical and Dentistry Sciences and Morphological and Functional Imaging, University of Messina, Messina, Italy.

Healthcare workers (HCWs) are at increased risk of being infected with SARS-CoV-2, yet limited information is available on risk factors of infection. We pooled data on occupational surveillance of 10,654 HCW who were tested for SARS-CoV-2 infection in six Italian centers. Information was available on demographics, job title, department of employment, source of exposure, use of personal protective equipment (PPEs), and COVID-19-related symptoms.

View Article and Find Full Text PDF

Gluten-free meals in public catering.

Ann Ig

October 2021

Area Health Authority 3 of Turin, Italy - Prevention District - Service of food safety standards and human nutrition, hereinafter quoted as "SIAN of ASL TO 3".

Background: The Piedmont Region, the Food Hygiene and Nutrition Services of the Local Healthcare Authorities of the Piedmont Region (coordinated by ASL TO 3), and the Italian Coeliac Association Piedmont Onlus, have created a theoretical-practical training pathway for Food Business Operators to ensure a safe gluten-free meal.

Study Design: The aim of the study is to perform a retrospective analysis of the data collected in order to assess whether the Food Business Operators will be able to manage in the short, medium and long term audits (3-month audits, 6-month audits and 1-year audits) all the production stages of a gluten-free meal (storage, production.

Methods: We have analysed the check-list used for assessing the gluten free meal, recorded from 2010 to 2016 by the staff of the Food Hygiene and Nutrition Services.

View Article and Find Full Text PDF

Background: In kidney transplant patients, polyomavirus-associated nephropathy (PVAN) represents a serious complication; the key factor for the development of PVAN is immunosuppression level and modulation of anti-rejection treatment represents the first line of intervention. Allograft biopsy and histology remain the criterion standard for diagnosing PVAN.

Methods: All consecutive renal biopsies with the diagnosis of PVAN carried out at the University Hospital City of Health and Science of Turin over a five-years period were studied.

View Article and Find Full Text PDF
Article Synopsis
  • Spinocerebellar ataxia 38 (SCA38) is linked to mutations in the ELOVL5 gene, leading to reduced levels of docosahexaenoic acid (DHA), a crucial fatty acid, which negatively impacts patients' health.* -
  • A study involving 10 SCA38 patients showed that after 16 weeks of DHA supplementation, clinical improvements were significantly greater compared to a placebo group, and continued benefits were observed after 40 weeks of treatment.* -
  • The research indicated that DHA is a safe and effective treatment for SCA38, resulting in improved clinical symptoms and brain function without any reported side effects.*
View Article and Find Full Text PDF