38 results match your criteria: "University Hospital Center of Limoges[Affiliation]"

Folliculogenesis resumption after ovarian cortex transplantation: what is the earliest hormonal indicator?

Arch Gynecol Obstet

December 2024

Department of Assisted Reproductive Technologies and Fertility Preservation, Jeanne de Flandre Hospital, CHU Lille, 59000, Lille, France.

Introduction: Ovarian tissue cryopreservation (OTC) is recommended by scientific societies for women undergoing highly gonadotoxic cancer treatments. Following transplantation, the restoration of ovarian function is typically characterised by the resumption of spontaneous menstruation. Yet, a few studies have looked at the longitudinal hormonal variations following transplantation.

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Impact of age on surgical excision margins for vulvar squamous cell carcinomas: A multicenter study by the francogyn group.

Surg Oncol

November 2024

ECEVE U1123, National Institute of Health and Medical Research, Paris Cité University, Paris, France; Department of Obstetrics and Gynaecology, Lariboisiere University Hospital, University Paris Cité, Assistance Publique des Hôpitaux de Paris (AP-HP), Paris, France.

Article Synopsis
  • Vulvar cancer primarily affects older women and requires surgical treatment, with guidelines emphasizing the importance of negative histological margins.
  • A study analyzed the impact of patient age on surgical outcomes, finding that older patients (≥65 years) had larger tumors but similar rates of negative excision margins compared to younger patients (<65 years).
  • Results indicated that younger patients experienced better recurrence-free survival and were more likely to undergo revision surgery despite the older group receiving more radical surgery.
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Objective: Previous studies assessing factors associated with drug-resistant epilepsy (DRE) were constrained by their amalgamation of all epilepsy syndromes in their analyses and the absence of uniform criteria for defining DRE. Our objective was to identify predictors of DRE among the four primary childhood epilepsy syndrome groups within a cohort of children with new onset seizures, using the International League Against Epilepsy (ILAE) definition of DRE and the recent classification of epilepsies.

Methods: This is a prospective study of 676 children with new onset seizures initiated on antiseizure medication.

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Prevalence of neuropathic pain in patients with symptomatic endometriosis: Assessment using the DN4 score.

Eur J Obstet Gynecol Reprod Biol

September 2024

Department of Gynecology and Obstetrics, Mother and Child Hospital, University Hospital Center of Limoges, 87000 Limoges, France; Pharmacology and Transplantation, INSERM U1248, Université de Limoges, 2 Rue du Pr Descottes, 87000 Limoges, France. Electronic address:

The mechanisms underlying pain in cases of endometriosis or chronic pelvic pain are complex, often involving various types of pain; mainly nociceptive pain, central sensitization, and neuropathic pain. Our main objective was to examine the prevalence of neuropathic pain in women with symptomatic endometriosis, and secondary, to explore the factors associated with this type of pain and to assess the prevalence of a positive PPSC score and a history of sexual violence within this population. This study is a retrospective, comparative, single-center cohort study conducted from September 2019 to January 2023.

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Impact of age on tumor size in vulvar cancer: A multicenter study by the Francogyn group.

Eur J Surg Oncol

September 2024

ECEVE U1123, National Institute of Health and Medical Research, Paris Cité University, Paris, France; Department of Obstetrics and Gynaecology, Lariboisiere University Hospital, University Paris Cité, Assistance Publique des Hôpitaux de Paris (AP-HP), Paris, France.

Objective: Vulvar cancer is a rare pathology affecting mainly elderly women. This study aims to evaluate the impact of age on tumor size in vulvar cancer.

Material And Methods: This was a multicenter retrospective observational study carried out between January 1, 1998, and December 31, 2020, in patients operated on for vulvar cancer.

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Background: The objective of this study was to identify and qualify, by means of a three-dimensional kinematic analysis, the postures and movements of obstetricians during a simulated forceps birth, and then to study the association of the obstetricians' experience with the technique adopted.

Method: Fifty-seven volunteer obstetricians, 20 from the Limoges and 37 from the Poitiers University hospitals, were included in this multi-centric study. They were classified into 3 groups: beginners, intermediates, and experts, beginners having performed fewer than 10 forceps deliveries in real conditions, intermediates between 10 and 100, and experts more than 100.

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Paraspinal schwannoma.

Joint Bone Spine

September 2024

Neurosurgery Unit, University Hospital Center of Limoges, Limoges, France; CAPTuR, INSERM, University of Limoges, Limoges, France.

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Article Synopsis
  • One-third of COVID-19 patients deteriorate after emergency department admission, necessitating effective prognosis assessments to predict worsening conditions.
  • Current predictive biomarkers include lymphopenia and the PaO2/FiO2 ratio, while markers like immature granulocytes and monocyte differentiation did not show predictive value.
  • A combined score using decreased P/F ratio, lymphopenia, and loss of mHLA-DR proved effective in predicting patient outcomes, pointing to the importance of early immunosuppression monitoring in COVID-19 cases.
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Validation of the Borg CR10 Scale for the evaluation of shoulder perceived fatigue during work-related tasks.

Appl Ergon

April 2024

Center for Interdisciplinary Research in Rehabilitation and Social Integration (Cirris). Québec, QC, Canada; Department of Rehabilitation, Faculty of Medicine, Université Laval. Québec, QC, Canada. Electronic address:

Work-related upper extremity disorders (WRUEDs) are highly prevalent and costly. Development of fatigue is thought to be one of the causes of WRUEDs. Perceived fatigue can be assessed with the Borg CR Scale® (Borg CR10).

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Estimation of the prevalence of uterine infertility and its different causes in France according to data from a literature review.

J Gynecol Obstet Hum Reprod

December 2023

Department of Gynecology and Obstetrics, Mother and Child Hospital, University Hospital Center of Limoges, Limoges 87000, France; Pharmacology and Transplantation, INSERM U1248, Université de Limoges, 2 Rue du Pr Descottes, Limoges 87000, France. Electronic address:

Introduction: Uterine infertility (UI) is defined as the complete absence of a uterus (absolute uterine infertility or AUI) or the presence of a non functional uterus (non-absolute uterine infertility or NAUI). The exact prevalence of uterine infertility is currently unknown. Our aim was to assess the number of French women concerned by Uterine Infertility according to a recent literature review.

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A new approach to assessing the obstetrician's posture and movement during an instrumental forceps delivery.

J Gynecol Obstet Hum Reprod

November 2023

Department of Obstetrics and Gynecology, University Hospital Center of Poitiers, 2 rue de la Milétrie, CS 90577, 86021 Poitiers Cedex, France; Clinical investigation center, INSERM CIC 1402, Entrée 5 - Cours Est Jean Bernard CHU de Poitiers 2 rue de la Milétrie 86000 Poitiers, France; Motricité Interaction Performance, EA 4334, University of Nantes, 23 rue du Recteur Schmitt Bâtiment F0 - BP 92235 44322 Nantes France.

Introduction: The number of deliveries by forceps decreases significantly in favour of the vacuum. Now, when the use of forceps is necessary, physicians less experimented with this procedure are likely to induce serious and preventable perineal or foetal injuries. Training therefore becomes essential.

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Before ambulatory thyroidectomy is proposed, the patient and his family and/or friends will need to be informed by the surgeon of the specificity of this procedure, the normal postoperative effects of a thyroidectomy, and potential complications. Also known as outpatient thyroid surgery, it can only be proposed by an experienced surgeon supported by an adequately trained medical and paramedical team. The healthcare establishment must be in possession of all the resources needed in ambulatory management, with continuity of care guaranteed 24h/24 7d/7 in the event of possible emergency rehospitalization.

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Objective: To assess the impact of cognitive Dual Task (DT) during walking on the energy cost of walking (Cw) in individuals with subacute stroke. The secondary objective was to determine whether there is an association between the Cw and cortical activity of the prefrontal area.

Methods: Any individual with stroke localized in the temporal-parietal regions and able to walk without human assistance was included.

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Background and objective: Duration of rehabilitation and active participation are crucial for gait rehabilitation in the early stage after stroke onset. Virtual reality (VR) is an innovative tool providing engaging and playful environments that could promote intrinsic motivation and higher active participation for non-ambulatory stroke patients when combined with robot-assisted gait training (RAGT). We have developed a new, fully immersive VR application for RAGT, which can be used with a head-mounted display and wearable sensors providing real-time gait motion in the virtual environment.

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Uterine Factor Infertility, a Systematic Review.

J Clin Med

August 2022

Department of Gynecology and Obstetrics, Mother and Child Hospital, University Hospital Center of Limoges, 87000 Limoges, France.

Uterine factor infertility (UFI) is defined as a condition resulting from either a complete lack of a uterus or a non-functioning uterus due to many causes. The exact prevalence of UFI is currently unknown, while treatments to achieve pregnancy are very limited. To evaluate the prevalence of this condition within its different causes, we carried out a worldwide systematic review on UFI.

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Article Synopsis
  • Telerehabilitation, particularly through exergaming technology, is being used to help stroke patients with upper limb impairments improve their mobility and engage in enjoyable training exercises at home.
  • The review assesses user compliance with exercise programs based on how often patients complete prescribed sessions and how many drop out or discontinue the exercises.
  • Results show high compliance rates, but dropout reasons often stem from external factors or tech issues; there's a need for long-term follow-ups and better understanding of support systems like home visits.
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A 6-Month Home-Based Functional Electrical Stimulation Program for Foot Drop in a Post-Stroke Patient: Considerations on a Time Course Analysis of Walking Performance.

Int J Environ Res Public Health

July 2022

PRISMATICS Lab (Predictive Research in Spine/Neuromodulation Management and Thoracic Innovation/Cardiac Surgery), Poitiers University Hospital, 86000 Poitiers, France.

Foot drop is a common disability in post-stroke patients and represents a challenge for the clinician. To date, ankle foot orthosis (AFO) combined with conventional rehabilitation is the gold standard of rehabilitation management. AFO has a palliative mechanical action without actively restoring the associated neural function.

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After failure of first line FOLFOX-bevacizumab for metastatic colorectal cancer (mCRC), adding either bevacizumab or aflibercept to second-line FOLFIRI increases survival compared to FOLFIRI alone. In this French retrospective multicentre cohort, we included patients with a mCRC treated with either FOLFIRI-aflibercept or FOLFIRI-bevacizumab. The primary endpoint was overall survival (OS), and secondary endpoints were progression-free survival (PFS), disease control rate (DCR: CR + PR + SD) and safety.

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Article Synopsis
  • * This randomized clinical trial will compare the combined use of RGS and standard care against standard care alone, monitoring patient recovery over a 3-month period and evaluating outcomes at multiple intervals.
  • * Researchers anticipate that the RGS solution will enhance patient recovery, receive high acceptance rates, and minimize healthcare costs by easing the transition from hospital to home rehabilitation.
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Article Synopsis
  • Increased energy costs of walking (Cw) in stroke patients are linked to their walking ability and independence, but the effect on their quality of life (QoL) has not been previously explored.
  • A study with 37 stroke patients found that higher Cw significantly impacted QoL assessments taken after hospital discharge, particularly at six months and one year later.
  • The findings suggest that both Cw and mood disorders (measured by HADS) are important predictors of QoL, emphasizing the need for early interventions to improve these factors for better long-term outcomes.
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First Systematic Review and Meta-analysis of the Validity and Test-Retest Reliability of Physical Activity Monitors for Estimating Energy Expenditure During Walking in Individuals With Stroke.

Arch Phys Med Rehabil

November 2022

Department of Physical Medicine and Rehabilitation in the University Hospital Center of Limoges, Limoges; HAVAE UR20217 (Handicap, Aging, Autonomy, Environment), FEDRHA, University of Limoges, Limoges. Electronic address:

Objective: To evaluate the validity and test-retest reliability of physical activity trackers (accelerometer, multisensor, smartphone, pedometer) for estimating energy expenditure during walking in individuals with stroke.

Data Sources: Webline, MEDLINE, Scopus, ScienceDirect, Bielefeld Academic Search Engine, and Wiley Online Library databases from 1980 to November 2020.

Study Selection: The inclusion criteria were studies that examined the validity of portable physical activity trackers for estimating energy expenditure in individuals with stroke during walking activities compared to indirect calorimetry.

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Background: The integration of oxygen cost into the accelerometer's algorithms improves accuracy of total energy expenditure (TEE) values as post-stroke individuals walk. Recent work has shown that oxygen cost can be estimated from specific prediction equations for stroke patients.

Objective: The objective is to the validity of the different oxygen cost estimation equations available in the literature for calculating TEE using ActigraphGT3x as individuals with stroke sequelae walk.

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Equations for estimating the oxygen cost of walking in stroke patients: Systematic review.

Ann Phys Rehabil Med

January 2022

HAVAE EA6310 (Handicap, Aging, Autonomy, Environment), IFRH, University of Limoges, 87042 Limoges, France.

Objective: To report all equations that can potentially be used to estimate the oxygen cost of walking (Cw) without using a respiratory gas exchange analyzer and to provide the level of reliability of each equation.

Data Sources: Webline, Medline, Scopus, ScienceDirect, Bielefeld Academic Search Engine (BASE), and Wiley Online Library databases from 1950 to August 2019 with search terms related to stroke and oxygen cost of walking.

Methods: This systematic review was reported according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, and the methodological quality of included studies was determined with the Critical Appraisal Skills Programme (CASP).

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Objective: To evaluate the association between self-selected walking speed (S), oxygen consumption at S (Vo), the oxygen cost of walking (Cw) at S, and mobility independence and independence for activities of daily living in individuals poststroke.

Design: Cross-sectional study.

Setting: Hospital.

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Mobile phone use during pregnancy: Which association with fetal growth?

J Gynecol Obstet Hum Reprod

October 2020

Department of Gynecology and Obstetrics, University Hospital Center of Limoges, 8 Avenue Dominique Larrey, 87042 Limoges cedex, France.

Introduction: Few studies have investigated the effect of electromagnetic waves on the human fetus whereas nowadays mobile phone use is ubiquitous. The aim of this study was to evaluate the association between mobile phone use by pregnant women and fetal development during pregnancy in the general population.

Material And Methods: Data came from the NéHaVi cohort ("prospective follow-up, from intrauterine development to the age of 18 years, for children born in Haute-Vienne"), a prospective, longitudinal, multicenter (three maternity units in Haute-Vienne) observational cohort focusing on children born between April 2014 and April 2017.

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