2,121 results match your criteria: "University Hospital "Rijeka"[Affiliation]"

Article Synopsis
  • Rheumatoid arthritis (RA) patients often lose muscle and handgrip strength, which makes it hard for them to live normal lives.
  • This study looked at 267 RA patients in Croatia to see what factors, like their exercise habits and medications, affect their muscle strength.
  • It found that for women, things like weight, height, and exercise help improve muscle strength, while certain medications and severe symptoms make it worse.
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Article Synopsis
  • Infections are a major complication in treating children with acute lymphoblastic leukemia (ALL), with a study analyzing their characteristics in 23 pediatric patients over five years.
  • A total of 104 infectious episodes (IEs) were reported, primarily affecting the respiratory tract, and were more common during intensive treatment phases, with neutropenia present in nearly half of the cases.
  • The study highlighted the importance of quick antibiotic response and personalized treatment adjustments to lower infection risks, ensuring no infection-related deaths occurred among the patients.
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Aim: Our goal was to examine the effect of high-intensity physical activity on changes in the lipid profile, complete blood count (CBC), iron metabolism, and kidney and liver function tests of professional water polo players.

Methods: This study included twenty professional male water polo players. Blood sampling was carried out at the beginning of the season and during periods of high-intensity training.

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Background: Arterial hypertension (AH) is a significant risk factor for cardiovascular disease and is associated with increased arterial stiffness, particularly as measured by pulse wave velocity (PWV). This study aims to explore the relationships between age groups, antihypertensive and new oral antidiabetic drugs, body composition, and arterial stiffness parameters in hypertensive patients.

Methods: A single-center cross-sectional study was conducted including 584 participants who underwent 24 h ambulatory blood pressure monitoring (including central blood pressure (BP) and PWV measurement), body composition analysis, and provided medical history and current pharmacotherapy data.

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Combinatory Effect of Nitroxoline and Gentamicin in the Control of Uropathogenic Enterococci Infections.

Antibiotics (Basel)

September 2024

Department of Medical Chemistry, Biochemistry and Clinical Chemistry, Faculty of Medicine, University of Rijeka, 51000 Rijeka, Croatia.

, responsible for a majority of human and nosocomial enterococcal infections, is intrinsically resistant to aminoglycoside antibiotics (such as gentamicin, GEN), which must be used in a combined therapy to be effective. Nitroxoline (NTX) is an old antibiotic, underused for decades, but rediscovered now in an era of growing antibiotic resistance. In this in vitro study, the types of interactions between NTX and GEN on 29 strains were analyzed with an aim to find synergistic antimicrobial and antiadhesion combinations.

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Nationwide evaluation of treatment outcomes and survival of patients with non-tuberculous mycobacterial pulmonary disease.

Int J Tuberc Lung Dis

October 2024

Radboud Center for Infectious Diseases, Department of Medical Microbiology, Radboud University Nijmegen Medical Centre, Nijmegen, the Netherlands.

BACKGROUNDTreatment outcomes and long-term survival of non-tuberculous mycobacterial pulmonary disease (NTM-PD) in a real-world setting are difficult to assess, especially for species other than complex (MAC).METHODSThis was a retrospective cohort study on all Croatian residents with respiratory NTM isolates from 2006 to 2015, with follow-up to 2020.RESULTSTherapy was started in 98/137 (71.

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Instrumental activities of daily living in neuro-oncology: International validation of the EORTC IADL-BN32 questionnaire.

Eur J Cancer

November 2024

Department of Neurology, Haaglanden Medical Center, The Hague, the Netherlands; Department of Neurology, Leiden University Medical Center, Leiden, the Netherlands.

Background: Neurocognitive impairments are common in patients with a brain tumour, and may negatively impact on functioning in daily life, particularly on instrumental activities of daily living (IADL). The EORTC IADL-BN32 questionnaire was developed to measure IADL in this patient population.

Methods: In this international validation study, we evaluated the EORTC IADL-BN32 questionnaire on several psychometric properties in a large sample of patients with a primary or metastatic brain tumour.

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The aim of this study was to evaluate the efficacy of autologous dentin (AD), bovine xenograft (BX) and magnesium-enriched bovine xenograft (BX + Mg) in the healing of critical cranial bone defects (CCBDs) in rats. Eighty male Wistar rats were divided into four groups: BX, BX + Mg, AD and the control group (no intervention). Eight mm CCBDs were created and treated with the respective biomaterials.

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Surgical management of anastomotic leakage related to ovarian cancer surgery: a narrative review.

Front Surg

September 2024

Department of Medical Area (DMED), Clinic of Obstetrics and Gynecology Unit, Santa Maria Della Misericordia Hospital, Azienda Sanitaria Friuli Centrale, Udine, Italy.

This narrative review describes the state of the art in the management of anastomotic leakage in ovarian cancer. Multiple surgical procedures, including bowel resection, are often required to achieve "optimal" cytoreduction in locally advanced ovarian cancer. Intestinal anastomosis is currently the most common way to restore bowel continuity.

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Article Synopsis
  • The study investigates the effectiveness of technetium-99m (99mTc)-labelled Methoxy-2-Isobutylisonitrile (MIBI) in diagnosing amiodarone-induced thyrotoxicosis (AIT) through various medical tests, including thyroid scintigraphy and ultrasonography.
  • It included 36 AIT patients who underwent multiple analyses, and results showed that semi-quantitative MIBI analysis was more effective in differentiating between AIT subtypes compared to visual analysis.
  • The findings suggest that while visual analysis is helpful, semi-quantitative methods provide improved accuracy, indicating the need for larger studies to standardize diagnostic approaches.
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Sex dependence of postoperative pulmonary complications - A post hoc unmatched and matched analysis of LAS VEGAS.

J Clin Anesth

December 2024

Amsterdam University Medical Center, Department of Anaesthesiology, Meibergdreef 9, 1105AZ Amsterdam, the Netherlands; Amsterdam University Medical Center, Department of Intensive Care, Meibergdreef 9, 1105AZ Amsterdam, the Netherlands.

Article Synopsis
  • The study aimed to investigate whether there are differences in postoperative pulmonary complications (PPCs) between males and females following surgery under general anesthesia, using data from the LAS VEGAS study involving 146 hospitals across 29 countries.
  • A total of 9,697 patients were analyzed in two cohorts: an unmatched cohort (55.1% female, 44.9% male) and a matched cohort (50% female and male), finding no significant differences in PPC rates between the genders in both cohorts.
  • The study concluded that, in this international patient population, the incidence of PPCs did not differ significantly between males and females, as well as noting comparable hospital stays and mortality rates.*
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Sexual health-related psychological and emotional life after allogeneic haematopoietic stem-cell transplantation.

Lancet Haematol

October 2024

Sorbonne University, Paris, France; Department of Hematology and Cellular Therapy, Saint-Antoine Hospital, Assistance Publique-Hôpitaux de Paris, Paris, France; INSERM, Unité Mixte de Recherche 938, Paris, France.

Sexual health is important for the quality of life of patients who have received haematopoietic stem-cell transplantation (HSCT). Sexual dysfunction and couple dissatisfaction can seriously affect a patient's recovery and treatment process. However, this aspect of post-transplantation recovery is still usually neglected in clinical practice.

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The perception of the risk of sexually transmitted infections (STIs) is a well-researched phenomenon, but not in relation to cyberchondria and health literacy. Therefore, our aim was to examine the association between the assessment of the risk of sexually transmitted diseases and HIV, cyberchondria, and health literacy. : This study was conducted in 2020-2021 in Croatia.

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VALIDATION OF THE QUALITY OF RECOVERY-40 QUESTIONNAIRE ADAPTED FOR CROATIAN POPULATION.

Acta Clin Croat

November 2023

Department of Anesthesiology and Perioperative Medicine, School of Medicine, University of Missouri, Columbia, MO, USA.

Quality of recovery after anesthesia is an important indicator of patient postoperative outcomes. Quality of Recovery-40 (QoR-40) is a validated and widely used multidimensional 40-item questionnaire that measures postoperative quality of recovery. The aim of this study was to perform translation and psychometric validation of the Croatian version of QoR-40, which included validity, reliability, responsiveness, and clinical acceptability.

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Background: Bortezomib, dexamethasone and cyclophosphamide (VCd) remains a popular regimen, due to its activity and low toxicity, while bortezomib, lenalidomide and dexamethasone (VRd) is widely used in US and Europe; both are combined with anti-CD38 monoclonal antibodies but VCd and VRd have not been compared directly in adequately powered prospective trials.

Aim: We compared the outcomes of 1216 patients treated with VCd (N = 690) or VRd (N = 526) in a real-world setting.

Results: Patients treated with VCd had more often severe renal dysfunction, ISS-3 disease, hypercalcemia, elevated LDH, anemia, thrombocytopenia, poor performance while VRd-treated were older and received less often autologous transplant but more frequently maintenance but the duration of induction was similar.

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The endocannabinoid system in appetite regulation and treatment of obesity.

Pharmacol Res Perspect

October 2024

Department of Clinical Pharmacology and Toxicology, Clinical Hospital Centre Zagreb, Zagreb, Croatia.

The endocannabinoid system (ECS) is a complex cell-signaling system that is responsible for maintaining homeostasis by modulating various regulatory reactions in response to internal and environmental changes. The influence of ECS on appetite regulation has been a subject of much recent research, however, the full extent of its impact remains unknown. Current evidence links human obesity to ECS activation, increased endocannabinoid levels in both central and peripheral tissues, along with cannabinoid receptor type 1 (CBR1) up-regulation.

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Letter to the Editor Regarding 'Impact of the number of therapy lines on survival in advanced gastric and esophagogastric adenocarcinoma - a real-world retrospective analysis from Croatia', published in Neoplasma 2024; 71: 201-208. https://doi.org/10.

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Sudden, unexpected deaths are extremely difficult for families, especially when the victim is a child. Most sudden deaths occur due to cardiovascular issues, and a smaller number (approximately one-quarter) are attributed to other causes, such as epilepsy. The medicinal and non-medicinal use of the synthetic opioid fentanyl, which can cause breathing problems, is frequently involved in these deaths.

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Education and cooking methods in the management of calcium and PTH serum levels in patients on hemodialysis: a randomized controlled study.

J Nephrol

September 2024

Faculty of Food Technology and Biotechnology, Department of Food Quality Control, University of Zagreb, Pierottijeva 6, 10 000, Zagreb, Croatia.

Background: Chronic kidney disease associated mineral bone disorder (CKD-MBD) is one of the major causes of excess morbidity and mortality in hemodialysis patients. The purpose of this study was to investigate whether education about dietary intakes and specific food processing methods affect serum calcium and PTH concentrations in hemodialysis patients.

Methods: Forty-seven hemodialysis patients were randomly divided into a control and an intervention group.

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The Impact of the COVID-19 Pandemic on Individuals with Down Syndrome: A Croatian Survey.

Balkan J Med Genet

June 2024

Department of Medical Biology and Genetics, Faculty of Medicine, University of Rijeka, Rijeka, Croatia.

Background: Severe acute respiratory syndrome coronavirus-2 infection has spread uncontrollably worldwide. Among the most vulnerable groups in society are populations with multiple comorbidities, including individuals with Down syndrome (DS).

Aim: Our aim was to conduct an online survey to assess the impact of COVID-19 on DS individuals in Croatia.

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Introduction: Smoking has a negative impact on the chemosensory function. The aim of the study was to evaluate the effects of smoking experience and type of tobacco products on gustatory and olfactory function.

Methods: This study included 30 conventional cigarette smokers, 30 heated tobacco products (HTPs) users, and 30 non-smokers.

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Left bundle branch pacing has recently emerged as a significant alternative to right ventricular pacing. The rate of implanted stylet-driven septal leads is expected to increase substantially in the coming years, along with the need to manage long-term complications. Experience in extracting these leads is currently very limited; however, the number of complex extractions is anticipated to increase in the future.

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Background: The interplay between peritoneal dialysis (PD), residual kidney function (RKF), and thyroid function remains poorly understood, with limited prospective studies comparing thyroid function in PD versus hemodialysis (HD) patients.

Methods: This prospective single-center study assessed thyroid function in 18 PD patients over a 24-month follow-up period at the Department of Nephrology, Dialysis, and Kidney Transplantation, UHC Rijeka, Croatia. Data were compared to 24 concurrently treated HD patients.

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Background: Health workers' (HWs') perspectives on the quality of maternal and newborn care (QMNC) are not routinely collected. In this cross-sectional study, we aimed to document HWs' perspectives on QMNC around childbirth in 12 World Health Organization (WHO) European countries.

Methods: HWs involved in maternal/neonatal care for at least one year between March 2020 and March 2023 answered an online validated WHO standards-based questionnaire collecting 40 quality measures for improving QMNC.

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