6 results match your criteria: "University Hospital "Central de Asturias" and ISPA[Affiliation]"

Patients With Psoriatic Arthritis-Related Enthesitis and Persistence on Tofacitinib Under Real-World Conditions.

J Rheumatol

July 2024

R. Queiro, MD, PhD, Rheumatology Division, Hospital Universitario Central de Asturias, and Oviedo University School of Medicine, and ISPA Translational Immunology Division, Oviedo-Asturias, Spain.

Objective: Information on the persistence of tofacitinib (TOF) in psoriatic arthritis (PsA) is scarce in real-world conditions. Our objective was to analyze the persistence and safety of TOF under these conditions.

Methods: This was a single-center retrospective longitudinal observational study of all patients with PsA who received at least 1 dose of TOF.

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Management of Axial Disease in Patients With Psoriatic Arthritis: An Updated Literature Review Informing the 2021 GRAPPA Treatment Recommendations.

J Rheumatol

February 2023

D.D. Gladman, MD, University of Toronto, and Schroeder Arthritis Institute, Krembil Research Institute, Toronto Western Hospital, Toronto, Ontario, Canada.

Objective: Axial involvement in patients with psoriatic arthritis (PsA) is a common subset of this condition, but a unanimous definition has yet to be established. It has been defined by using different criteria, ranging from the presence of at least unilateral grade 2 sacroiliitis to those used for ankylosing spondylitis (AS), or simply the presence of inflammatory low back pain (IBP). Our aim was to identify and evaluate the efficacy of therapeutic interventions for treatment of axial disease in PsA.

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Background: Previous studies comparing immigrant ethnic groups and native patients with IBD have yielded clinical and phenotypic differences. To date, no study has focused on the immigrant IBD population in Spain.

Methods: Prospective, observational, multicenter study comparing cohorts of IBD patients from ENEIDA-registry who were born outside Spain with a cohort of native patients.

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Article Synopsis
  • A study of 73,881 mother-child pairs in Europe explored the relationship between early acetaminophen exposure and the development of Autism Spectrum Conditions (ASC) and Attention-Deficit/Hyperactivity Disorder (ADHD).
  • The findings suggest that children exposed to acetaminophen before birth had a 19% and 21% higher likelihood of exhibiting borderline or clinical symptoms of ASC and ADHD, respectively, with boys showing slightly higher odds.
  • Postnatal acetaminophen exposure did not show a link to ASC or ADHD symptoms, indicating the need for clear risk communication regarding acetaminophen use during pregnancy.
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Introduction: Acute ischemic strokes with tandem occlusions, which represent 10-20% of all ischemic strokes, have a particularly poor prognosis. Since emergent treatment of tandem lesions has not been specifically addressed in randomized trials, there is an absence of standardized management.

Objective: We sought to assess the efficacy and safety of acute endovascular treatment in stroke due to tandem occlusions in our center and compare the results with previous reports.

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