Evaluating different stressors among parents with hospitalized children.

Background: The pediatric hospital is an environment with a high level of stress for most parents. Parents experience high levels of stress if their children are hospitalized due to the fear for the loss of their child's life.

Objective: The objective of this study was to evaluate stress factors in parents of hospitalized children.

Diagnostic Accuracy of Doppler Ultrasound in Predicting Perinatal Outcome in Appropriate for Gestational Age Fetuses: A Prospective Study.

Objective:  To elucidate the role of Doppler ultrasound in predicting perinatal outcome in appropriate for gestational age (AGA) fetuses at term.

Material And Methods:  Prospective study carried out in a dedicated research ultrasound clinic. The inclusion criterion was AGA fetuses, defined as those with an estimated fetal weight between the 10 and 90 percentile, at 36 + 0-37 + 6 weeks of gestation.

Experience of an Italian Hospital Claims Management Committee: A tool for extrajudicial litigations resolution.

Litigation related to medical liability has a great impact on Italian healthcare expenditure. Recently, many Italian Regions have adopted a "self-insurance system" and, in Sicilian Hospitals, were established the Claims Management Committees (CMC) to provide the direct management of claims. Here the experience of a Sicilian University Hospital CMC was described to analyze the claims features and their outcomes providing evidence on CMC usefulness.

Evaluating Therapy Treatments in Patients with Mental Disorders in Relation to Oral Health.

Aim: The purpose of this study was to find the correlation between dental caries and teeth loss in relation to gender, age, treatments with different therapies, time period being hospitalized, sugar consumption, smoking, and oral hygiene in mental disordered patients.

Objective: Evaluating therapeutic treatments in patients with mental illnesses, focusing on the effects on oral health.

Materials And Methods: This is a longitudinal cohort study conducted on patients who have been hospitalized from 5 years to 30 years.

A Systematic Review of Survival Rates of Osseointegrated Implants in Fully and Partially Edentulous Patients Following Immediate Loading.

Background: The aim of this systematic review was to evaluate the survival rates of immediately loaded implants after at least five years. Besides implant failure, the amount of marginal bone loss around implants and the complication type were assessed.

Methods: The electronic search was undertaken on Medline, Scopus, and Cochrane Central Register of Controlled Trials using key terms such as: "immediate loading", "immediate function", "immediate restoration", "immediate temporization", "dental implants", "fully edentulous patients", "partially edentulous patients".

Transverse tubule remodeling enhances Orai1-dependent Ca entry in skeletal muscle.

Exercise promotes the formation of intracellular junctions in skeletal muscle between stacks of sarcoplasmic reticulum (SR) cisternae and extensions of transverse-tubules (TT) that increase co-localization of proteins required for store-operated Ca entry (SOCE). Here, we report that SOCE, peak Ca transient amplitude and muscle force production during repetitive stimulation are increased after exercise in parallel with the time course of TT association with SR-stacks. Unexpectedly, exercise also activated constitutive Ca entry coincident with a modest decrease in total releasable Ca store content.

Clinical and in vivo confocal microscopic features of neuropathic corneal pain.

Aims: To describe clinical and in vivo confocal microscopy (IVCM) features of neuropathic corneal pain (NCP) without clinically visible signs.

Methods: Prospective, observational study of 27 eyes of 14 patients who had continuous severe ocular pain for one or more years, with minimal or no ocular surface signs and were non-responsive to topical lubricants, steroids and/or ciclosporin. All patients were evaluated using Ocular Surface Disease Index, Oxford grading scale, Schirmer test 1, Cochet Bonnet esthesiometry and response to topical anaesthesia.

Synthetic Blocks for Bone Regeneration: A Systematic Review and Meta-Analysis.

This systematic review is aimed at evaluating the effectiveness of synthetic block materials for bone augmentation in preclinical in vivo studies. An electronic search was performed on Pubmed, Scopus, EMBASE. Articles selected underwent risk-of-bias assessment.

Modulation of Apoptotic Cell Death and Neuroprotective Effects of Glutathione-L-Dopa Codrug Against HO-Induced Cellular Toxicity.

The L-3,4-dihydroxyphenylalanine (LD) is the gold standard drug currently used to manage Parkinson's disease (PD) and to control its symptoms. However, LD could cause disease neurotoxicity due to the generation of pro-oxidant intermediates deriving from its autoxidation. In order to overcome this limitation, we have conjugated LD to the natural antioxidant glutathione (GSH) to form a codrug (GSH-LD).

Modulation of CAT-2B-Mediated l-Arginine Uptake and Nitric Oxide Biosynthesis in HCT116 Cell Line Through Biological Activity of 4'-Geranyloxyferulic Acid Extract from Quinoa Seeds.

is a "pseudocereal" grain which attracts a lot of attention in the scientific community as it has a positive effect on health. Here, we investigate the presence of biologically active O-prenylated phenylpropanoids in the ethanol extract of commercially available quinoa seeds. We claim that 4'-Geranyloxyferulic acid (GOFA) was the only phytochemical product found that belongs to quinoa's group secondary metabolites.

Prognostic value of morning surge of blood pressure in middle-aged treated hypertensive patients.

We investigated the prognostic value of morning surge (MS) of blood pressure (BP) in middle-aged treated hypertensive patients. The occurrence of a composite end point (coronary events, stroke, and heart failure requiring hospitalization) was evaluated in 1073 middle-aged treated hypertensive patients (mean age 49 years). Patients with preawakening MS of BP above the 90th percentile (27/20.

Evaluation of Caries Prevalence and Decayed-, Missing-, and Filled-teeth Values in Permanent Dentition in Children 7 to 10 Years Old-A Longitudinal Study.

Aim: To evaluate the correlation between age and caries development in permanent teeth, as well as to show the trends of decayed, missing, and filled teeth (DMFT) index in Albania.

Materials And Methods: Subsequent observations hold from July 2016-July 2018. Our study included 393 children of the age range of 7-10 years old.

The impact of perioperative care on complications and short term outcome in ARM type rectovestibular fistula: An ARM-Net consortium study.

Background: The impact of perioperative care interventions on postreconstructive complications and short-term colorectal outcome in patients with anorectal malformation (ARM) type rectovestibular fistula is unknown.

Methods: An ARM-Net consortium multicenter retrospective cohort study was performed including 165 patients with a rectovestibular fistula. Patient characteristics, perioperative care interventions, timing of reconstruction, postreconstructive complications and the colorectal outcome at one year of follow-up were registered.

Sexual Function following Laparoscopic versus Transvaginal Closure of the Vaginal Vault after Laparoscopic Hysterectomy: Secondary Analysis of a Randomized Trial by the Italian Society of Gynecological Endoscopy Using a Validated Questionnaire.

Study Objective: The effect of the different types of vaginal cuff closures on posthysterectomy sexual function has not been investigated in depth. We evaluated if there is a difference between transvaginal versus a laparoscopic closure after total laparoscopic hysterectomy (TLH) on female sexual function, using a validated questionnaire.

Design: Secondary analysis of a prospective randomized controlled trial.

Training Loads and RSA and Aerobic Performance Changes During the Preseason in Youth Soccer Squads.

The aims of this study were to compare the internal training load (ITL) in soccer players of two competitive age groups (under-15 [U-15] and under-19 [U-19]) during an 8-week preseason training period and compare the associated changes in physical performance measures. Eighteen U-15 and twelve U-19 players were monitored over an 8-week period during the preseason phase. The ITL was monitored using the session rating of perceived exertion (RPE) method.

Different Pathways Leading up to the Same Futsal Competition: Individual and Inter-Team Variability in Loading Patterns and Preseason Training Adaptations.

During the preseason, futsal players deal with large internal load, which may result in a reduction in physical performance. The aims of this study were to compare the session rating of perceived exertion training load (s-RPE TL) during the preseason between two teams; and to analyze the changes on the delayed-onset muscle soreness (DOMS), aerobic- and speed-power characteristics in players accumulating different s-RPE TL (Low (LTL) vs. High (HTL)).

Prognostic Value of Masked Uncontrolled Hypertension.

The prognostic relevance of masked uncontrolled hypertension (MUCH) is incompletely clear, and its global impact on cardiovascular outcomes and mortality has not been assessed. The aim of this study was to perform a meta-analysis on the prognostic value of MUCH. We searched for articles assessing outcome in patients with MUCH compared with those with controlled hypertension (CH) and reporting adjusted hazard ratio and 95% CI.

Recovery following Rugby Union matches: effects of cold water immersion on markers of fatigue and damage.

We investigated the effect of postmatch cold-water immersion (CWI) on markers of muscle damage, neuromuscular fatigue, and perceptual responses within 72 h after a rugby match. Twenty-two professional male rugby players were randomized into CWI (10 °C/10 min; = 11) or control (CON: 30 min seated; = 11) groups. Activity profile from Global Positioning Satellite systems and postmatch rating of perceived exertion were measured to determined match load.

The Dark Side of the Moon: The Right Ventricle.

The aim of this review article is to summarize current knowledge of the pathophysiology underlying right ventricular failure (RVF), focusing, in particular, on right ventricular assessment and prognosis. The right ventricle (RV) can tolerate volume overload well, but is not able to sustain pressure overload. Right ventricular hypertrophy (RVH), as a response to increased afterload, can be adaptive or maladaptive.

Can you change my preferences? Effect of social influence on intertemporal choice behavior.

The present study presents a novel social observation paradigm to examine whether temporal discounting (TD) can be modulated in a specific direction. In particular, after estimating a baseline discount rate, we exposed subjects to a pattern of choice that was opposite to their baseline preferences, i.e.

A giant urinary bladder stone in the mummy of Lebanese Maronite Patriarch Joseph Tyan (1760-1820) and its environmental and nutritional implications.

Introduction: Historical sources and anthropological investigations, with the indispensable support of radiology, bring to light pathological evidence of the past.

Case Presentation: The purpose of this article is to present the radiological investigation conducted on the mummy of the Maronite Joseph Tyan (1760-1820), a famous patriarch who guided the Lebanese Maronite community during a critical period of its history. The natural mummy of the Patriarch was temporarily removed from its burial site to certify the degree of preservation.