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Article Synopsis
  • Hepatitis D virus (HDV) infection poses a significant public health problem globally, particularly in those also infected with hepatitis B virus (HBV), leading to more severe liver complications and higher mortality rates compared to HBV alone.
  • A study conducted in Romania from January to July 2022 enrolled adults with HBV to explore the epidemiology and risk factors associated with HBV/HDV coinfection, revealing a prevalence rate of 3.8% for HBV and 33.1% for coinfection among those tested.
  • Key risk factors for HBV/HDV coinfection included being female, having a history of imprisonment, being older at diagnosis, and having sexual contact with individuals known to have viral hepatitis
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The authors present a revision of the literature and also their own experience concerning extrahepatic manifestations in hepatitis C virus infection. A special attention receives the lymphotropism of HCV with mixed cryoglobulinemia and leukocytoclastic vasculitis, lichen planus and porphyria cutanea tarda.

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