1 results match your criteria: "University College of Medical Sciences and Guru Teg Bahadur Hospital Shahdara[Affiliation]"
Role of BRCA1 and BRCA2 gene mutations in epithelial ovarian cancer in Indian population: a pilot study.
Int J Biochem Mol Biol
June 2014
Department of Biochemistry, University College of Medical Sciences and Guru Teg Bahadur Hospital Shahdara, Delhi, India.
Article Synopsis
- - Ovarian cancer often goes undetected until advanced stages due to vague symptoms and is linked to genetic mutations, particularly in BRCA1 and BRCA2 genes associated with family history.
- - A study on 30 women with confirmed ovarian cancer found multiple genetic variants, including some novel ones, but did not identify the known BRCA founder mutations in the participants.
- - While BRCA mutations account for a significant portion of familial ovarian cancer cases, they only explain a fraction of the overall genetic risk, suggesting the involvement of other genetic factors like single nucleotide polymorphisms (SNPs).