9 results match your criteria: "University College of London Hospitals NHS Trust[Affiliation]"

Context: Endourological procedures frequently require fluoroscopic guidance, which results in harmful radiation exposure to patients and staff. One clinician-controlled method for decreasing exposure to ionising radiation in patients with urolithiasis is to avoid the use of intraoperative fluoroscopy during stone intervention procedures.

Objective: To comparatively assess the benefits and risks of "fluoroscopy-free" and fluoroscopic endourological interventions in patients with urolithiasis.

View Article and Find Full Text PDF

A State of the Art lecture titled "Etiology and Outcomes of Thrombotic Microangiopathies in Pregnancy" was presented at the International Society on Thrombosis and Haemostasis Congress in 2022. First, it is important to understand changes in laboratory parameters in normal pregnancy, including complement levels, specifically the increase in C3, C4, C3a, and C4a throughout pregnancy. Complement is critical in normal pregnancy for implantation and for placental development.

View Article and Find Full Text PDF

Aims: The aim of this study was to compare the preinjury functional scores with the postinjury preoperative score and postoperative outcome scores following anterior cruciate ligament (ACL) reconstruction surgery (ACLR).

Methods: We performed a prospective study on patients who underwent primary ACLR by a single surgeon at a single centre between October 2010 and January 2018. Preoperative preinjury scores were collected at time of first assessment after the index injury.

View Article and Find Full Text PDF

The aim of this study was to compare the functional and radiographic outcomes of arthroscopic single-bundle anterior cruciate ligament reconstruction (ACLR) using either the anteromedial (AM) portal technique or transtibial (TT) technique. We identified 404 patients who underwent arthroscopic ACLR by a single surgeon between January 2006 and December 2016 at our institution. The TT portal was utilized in femoral tunnel drilling in 202 patients (TT group) while the AM portal was used in 202 patients (AM group).

View Article and Find Full Text PDF

Age is an adverse prognostic factor in patients with heart failure. We aimed to assess the impact of age and noncardiac co-morbidities in the outcome of patients undergoing cardiac resynchronization therapy (CRT), and determine which of these two factors is the most important predictor of survival. The study involved a single-center retrospective assessment of 697 consecutive CRT implants during a 12-year period.

View Article and Find Full Text PDF
Article Synopsis
  • Dual-site right ventricular pacing (Dual RV) was studied as an alternative for heart failure patients where the coronary sinus lead could not be implanted during cardiac resynchronization therapy (CRT).
  • A 12-year retrospective assessment showed that patients using Dual RV had a higher rate of all-cause mortality or heart transplant compared to matched controls, indicating poorer long-term outcomes.
  • The use of Dual RV also led to significantly more cardiac device-related infections, suggesting it is less favorable than traditional CRT methods.
View Article and Find Full Text PDF

Transvenous Implantable Cardioverter-Defibrillator (ICD) Lead Performance: A Meta-Analysis of Observational Studies.

J Am Heart Assoc

October 2015

The Heart Hospital, University College of London Hospitals NHS Trust, London, United Kingdom (R.P., G.G.B., P.D.L.) University College of London, United Kingdom (A.I., P.D.L.) Barts Heart Centre, Barts Health NHS Trust, London, United Kingdom (R.P., P.D.L.).

Background: Despite the widespread use of implantable cardioverter-defibrillators (ICDs) in clinical practice, concerns exist regarding ICD lead durability. The performance of specific lead designs and factors determining this in large populations need clarification.

Methods And Results: The Medline, Embase, and Cochrane Collaboration databases were searched for studies including ≥2 of the most commonly implanted leads.

View Article and Find Full Text PDF

Objectives: The objective of this study was to investigate the feasibility of identifying heart failure patients who are less likely to benefit from implantable cardioverter-defibrillator (ICD) therapy among those eligible for primary prevention ICDs.

Background: The cost-effectiveness of ICDs in primary prevention may be improved dramatically.

Methods: Using a cause-of-death analysis approach, we evaluated the discriminative and predictive values of a risk score with regard to overall mortality and specific causes of death by examining 2,485 patients enrolled in the French Primary Prevention ICD program (2002 to 2012).

View Article and Find Full Text PDF

Chronic idiopathic pain syndromes.

Best Pract Res Clin Rheumatol

April 2006

Department of Rheumatology, University College of London Hospitals NHS Trust and Great Ormond Street Hospital NHS Trust, Arthur Stanley House, 40-50 Tottenham Street, London W1T 4NJ, UK.

In this review, we outline a rational approach to the complex problem of chronic idiopathic pain syndromes. We focus principally on musculoskeletal pain disorders and emphasize the differences between adults and children. The different nomenclatures in use are clarified and the epidemiology is examined.

View Article and Find Full Text PDF